Search Results - "Akinyi, Linnet"

Clinical Utility of Serum Levels of Ubiquitin C-Terminal Hydrolase as a Biomarker for Severe Traumatic Brain Injury by MONDELLO, Stefania, LINNET, Akinyi, WANG, Kevin K, BUKI, Andras, ROBICSEK, Steven, GABRIELLI, Andrea, TEPAS, Joseph, PAPA, Linda, BROPHY, Gretchen M, TORTELLA, Frank, HAYES, Ronald L

“…Brain damage markers released in cerebrospinal fluid (CSF) and blood may provide valuable information about diagnosis and outcome prediction after traumatic…”
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Elevated Levels of Serum Glial Fibrillary Acidic Protein Breakdown Products in Mild and Moderate Traumatic Brain Injury Are Associated With Intracranial Lesions and Neurosurgical Intervention by Papa, Linda, MDCM, MSc, Lewis, Lawrence M., MD, Falk, Jay L., MD, Zhang, Zhiqun, PhD, Silvestri, Salvatore, MD, Giordano, Philip, MD, Brophy, Gretchen M., PharmD, Demery, Jason A., PhD, Dixit, Neha K., PhD, Ferguson, Ian, BA, Liu, Ming Cheng, MD, MS, Mo, Jixiang, PhD, Akinyi, Linnet, MS, Schmid, Kara, PhD, Mondello, Stefania, MD, PhD, Robertson, Claudia S., MD, Tortella, Frank C., PhD, Hayes, Ronald L., PhD, Wang, Kevin K.W., PhD

“…Study objective This study examines whether serum levels of glial fibrillary acidic protein breakdown products (GFAP-BDP) are elevated in patients with mild…”
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Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury by Papa, Linda, Akinyi, Linnet, Liu, Ming Cheng, Pineda, Jose A, Tepas, Joseph J, Oli, Monika W, Zheng, Wenrong, Robinson, Gillian, Robicsek, Steven A, Gabrielli, Andrea, Heaton, Shelley C, Hannay, H Julia, Demery, Jason A, Brophy, Gretchen M, Layon, Joe, Robertson, Claudia S, Hayes, Ronald L, Wang, Kevin K. W

“…OBJECTIVE:Ubiquitin C-terminal hydrolase (UCH-L1), also called neuronal-specific protein gene product (PGP 9.3), is highly abundant in neurons. To assess the…”
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Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial lesions and neurosurgical intervention by Papa, Linda, Lewis, Lawrence M, Silvestri, Salvatore, Falk, Jay L, Giordano, Philip, Brophy, Gretchen M, Demery, Jason A, Liu, Ming Cheng, Mo, Jixiang, Akinyi, Linnet, Mondello, Stefania, Schmid, Kara, Robertson, Claudia S, Tortella, Frank C, Hayes, Ronald L, Wang, Kevin K W

“…This study compared early serum levels of ubiquitin C-terminal hydrolase (UCH-L1) from patients with mild and moderate traumatic brain injury (TBI) with…”
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αII-spectrin breakdown products (SBDPs): diagnosis and outcome in severe traumatic brain injury patients by Mondello, Stefania, Robicsek, Steven A, Gabrielli, Andrea, Brophy, Gretchen M, Papa, Linda, Tepas, Joseph, Robertson, Claudia, Buki, Andras, Scharf, Dancia, Jixiang, Mo, Akinyi, Linnet, Muller, Uwe, Wang, Kevin K W, Hayes, Ronald L

“…In this study we assessed the clinical utility of quantitative assessments of alphaII-spectrin breakdown products (SBDP145 produced by calpain, and SBDP120…”
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Ubiquitin C-terminal hydrolase-L1 as a biomarker for ischemic and traumatic brain injury in rats by Liu, Ming C., Akinyi, Linnet, Scharf, Dancia, Mo, Jixiang, Larner, Stephen F., Muller, Uwe, Oli, Monika W., Zheng, Wenrong, Kobeissy, Firas, Papa, Linda, Lu, Xi-Chun, Dave, Jitendra R., Tortella, Frank C., Hayes, Ronald L., Wang, Kevin K. W.

“…Ubiquitin C‐terminal hydrolase‐L1 (UCH‐L1), also called neuronal‐specific protein gene product 9.5, is a highly abundant protein in the neuronal cell body and…”
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Biochemical, Structural, and Biomarker Evidence for Calpain-Mediated Cytoskeletal Change After Diffuse Brain Injury Uncomplicated by Contusion by McGinn, Melissa J, Kelley, Brian J, Akinyi, Linnet, Oli, Monika W, Liu, Ming Cheng, Hayes, Ronald L, Wang, Kevin K.W, Povlishock, John T

“…Calpain-mediated degradation of the cytoskeletal protein α-II-spectrin has been implicated in the pathobiology of experimental and human traumatic brain injury…”
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Serum levels of Ubiquitin C-terminal Hydrolase (UCH-L1) distinguish mild traumatic brain injury (TBI) from trauma controls and are elevated in mild and moderate TBI patients with intracranial lesions and neurosurgical intervention by Papa, Linda, Lewis, Lawrence M., Silvestri, Salvatore, Falk, Jay L., Giordano, Philip, Brophy, Gretchen M., Demery, Jason A., Liu, Ming Cheng, Mo, Jixiang, Akinyi, Linnet, Mondello, Stefania, Schmid, Kara, Robertson, Claudia S., Tortella, Frank C., Hayes, Ronald L., Wang, Kevin K. W.

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Elevaed Levels of Serum Glial FibrillaryAcidic Protein Breakdown Products in Mild and Moderate Traumatic Brain Injury are Associated With Intracranial Lesions and Neurosurgical Intervention by Papa, Linda, Lewis, Lawrence M., Falk, Jay L., Zhang, Zhiqun, Silvestri, Salvatore, Giordano, Philip, Brophy, Gretchen M., Demery, Jason, Dixit, Neha K., Ferguson, Ian, Liu, Ming Cheng, Mo, Jixiang, Akinyi, Linnet, Schmid, Kara, Mondello, Stefania, Robertson, Claudia S., Tortella, Frank C., Hayes, Ronald L., Wang, Kevin K. W.

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Ubiquitin C-Terminal Hydrolase-L1as a Biomarker for Ischemic and Traumatic Brain Injury in Rats by Liu, Ming Cheng, Akinyi, Linnet, Scharf, Danica, Mo, Jixiang, Larner, Stephen F., Muller, Uwe, Oli, Monika W., Zheng, WenRong, Kobeissy, Firas, Papa, Linda, Lu, Xi-Chun, Dave, Jitendra R., Tortella, Frank C, Hayes, Ronald L., Wang, Kevin K. W.

“…Ubiquitin C-terminal hydrolase-L1 (UCH-L1), also called neuronal-specific protein gene product 9.5, is a highly abundant protein in neuronal cell body and has…”
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Biochemical, Structural and Biomarker Evidence for Calpain-Mediated Cytoskeletal Change Following Diffuse Brain Injury Uncomplicated by Contusion by McGinn, Melissa J., Kelley, Brian J., Akinyi, Linnet, Oli, Monika W., Liu, Ming Cheng, Hayes, Ronald L., Wang, Kevin K.W., Povlishock, John T.

“…Calpain-mediated degradation of the cytoskeletal protein alpha-II-spectrin has been implicated in the pathobiology of experimental and human traumatic brain…”
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