Search Results - "Akintayo, Christopher O."
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Short chain fatty acid, acetate restores ovarian function in experimentally induced PCOS rat model
Published in PloS one (26-07-2022)“…Background Polycystic ovarian syndrome (PCOS) is pathogenically characterized with hyperandrogenism and metabolic alterations, which often result in ovarian…”
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2
Protective role of melatonin against adipose-hepatic metabolic comorbidities in experimentally induced obese rat model
Published in PloS one (08-12-2021)“…Adipose and hepatic metabolic dysfunctions are critical comorbidities that also aggravate insulin resistance in obese individuals. Melatonin is a low-cost…”
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3
Combined effect of metformin and gallic acid on inflammation, antioxidant status, endoplasmic reticulum (ER) stress and glucose metabolism in fructose-fed streptozotocin-induced diabetic rats
Published in Toxicology reports (01-01-2021)“…[Display omitted] •Metformin, gallic acid and a combination of both improved glucose metabolism and antioxidant status in diabetic rats.•Metformin, gallic acid…”
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4
High fructose-enriched diet synergistically exacerbates endocrine but not metabolic changes in letrozole-induced polycystic ovarian syndrome in Wistar rats
Published in Heliyon (01-01-2021)“…Polycystic Ovarian Syndrome (PCOS) is a multifactorial endocrine-metabolic disorder that highly contributes to the prevalence of infertility globally. The…”
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5
Melatonin supplementation preserves testicular function by attenuating lactate production and oxidative stress in high fat diet-induced obese rat model
Published in Theriogenology (15-07-2022)“…Metabolic syndrome, including obesity has been documented as a critical factor in male reproductive dysfunction with subsequent reduction in male fertility…”
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6
Comparative effect of metformin and gliclazide on expression of some genes implicated in oxidative stress, endoplasmic reticulum stress, and inflammation in liver and pancreas of type 2 diabetic rats
Published in Comparative clinical pathology (01-02-2024)“…Oxidative stress, endoplasmic reticulum stress, and inflammation are implicated in both pathogenesis and progression of type 2 diabetes. This study aimed to…”
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7
The biological roles of urea: A review of preclinical studies
Published in Indian journal of nephrology (01-11-2022)“…Urea is an organic compound that has been reported to be effective against many pathological conditions. However, many other studies have reported the toxic…”
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8
Acetate supplementation restores testicular function by modulating Nrf2/PPAR-γ in high fat diet-induced obesity in Wistar rats
Published in Journal of diabetes and metabolic disorders (01-12-2021)“…Purpose Several studies have established impaired testicular function in obese male population, including the young males with childhood obesity, contributing…”
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9
Mineralocorticoid receptor blockade attenuates hyperandrogenic metabolic dysregulation in letrozole-induced PCOS rat model
Published in Journal of diabetes and metabolic disorders (15-07-2022)“…Purpose Polycystic ovarian syndrome (PCOS) is a metabolic syndrome associated with mineralocorticoid receptor (MR) activation, which causes infertility in…”
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10
Blockade of mineralocorticoid receptor by low-dose spironolactone rescues hypothalamic-ovarian dysfunction in PCOS experimental rat model
Published in Endocrine and metabolic science (01-12-2022)“…Studies have shown that women with polycystic ovarian syndrome (PCOS) undergo perturbations of the hypothalamic-pituitary ovarian axis, and frequently suffer…”
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11
Acetate supplementation restores testicular function by modulating Nrf2/PPAR-[gamma] in high fat diet-induced obesity in Wistar rats
Published in Journal of diabetes and metabolic disorders (21-10-2021)“…Purpose Several studies have established impaired testicular function in obese male population, including the young males with childhood obesity, contributing…”
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Journal Article -
12
Protective role of melatonin against adipose-hepatic metabolic comorbidities in experimentally induced obese rat model
Published in PloS one (01-01-2021)“…BackgroundAdipose and hepatic metabolic dysfunctions are critical comorbidities that also aggravate insulin resistance in obese individuals. Melatonin is a…”
Get full text
Journal Article