Search Results - "Akintayo, Christopher"

Short chain fatty acid, acetate restores ovarian function in experimentally induced PCOS rat model by Olaniyi, Kehinde S, Bashir, Al-amin M, Areloegbe, Stephanie E, Sabinari, Isaiah W, Akintayo, Christopher O, Oniyide, Adesola A, Aturamu, Ayodeji

“…Background Polycystic ovarian syndrome (PCOS) is pathogenically characterized with hyperandrogenism and metabolic alterations, which often result in ovarian…”
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Protective role of melatonin against adipose-hepatic metabolic comorbidities in experimentally induced obese rat model by Obayemi, Mary J, Akintayo, Christopher O, Oniyide, Adesola A, Aturamu, Ayodeji, Badejogbin, Olabimpe C, Atuma, Chukwubueze L, Saidi, Azeezat O, Mahmud, Hadiza, Olaniyi, Kehinde S

“…Adipose and hepatic metabolic dysfunctions are critical comorbidities that also aggravate insulin resistance in obese individuals. Melatonin is a low-cost…”
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The biological roles of urea: A review of preclinical studies by Adeyomoye, Olorunsola, Akintayo, Christopher, Omotuyi, Kolade, Adewumi, Adebukola

“…Urea is an organic compound that has been reported to be effective against many pathological conditions. However, many other studies have reported the toxic…”
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Melatonin supplementation preserves testicular function by attenuating lactate production and oxidative stress in high fat diet-induced obese rat model by Saidi, Azeezat O., Akintayo, Christopher O., Atuma, Chukwubueze L., Mahmud, Hadiza, Sabinari, Isaiah W., Oniyide, Adesola A., Aturamu, Ayodeji, Agunbiade, Toluwani B., Olaniyi, Kehinde S.

“…Metabolic syndrome, including obesity has been documented as a critical factor in male reproductive dysfunction with subsequent reduction in male fertility…”
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Comparative effect of metformin and gliclazide on expression of some genes implicated in oxidative stress, endoplasmic reticulum stress, and inflammation in liver and pancreas of type 2 diabetic rats by Obafemi, Tajudeen Olabisi, Alfa, Joy Achenyo, Obafemi, Blessing Ariyo, Jaiyesimi, Kikelomo Folake, Olasehinde, Oluwaseun Ruth, Adewale, Olusola Bolaji, Akintayo, Christopher O., Adu, Isaac Adekola

“…Oxidative stress, endoplasmic reticulum stress, and inflammation are implicated in both pathogenesis and progression of type 2 diabetes. This study aimed to…”
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Combined effect of metformin and gallic acid on inflammation, antioxidant status, endoplasmic reticulum (ER) stress and glucose metabolism in fructose-fed streptozotocin-induced diabetic rats by Obafemi, Tajudeen O., Jaiyesimi, Kikelomo F., Olomola, Adenike A., Olasehinde, Oluwaseun R., Olaoye, Oyindamola A., Adewumi, Funmilayo D., Afolabi, Blessing A., Adewale, Olusola B., Akintayo, Christopher O., Ojo, Oluwafemi A.

“…[Display omitted] •Metformin, gallic acid and a combination of both improved glucose metabolism and antioxidant status in diabetic rats.•Metformin, gallic acid…”
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Acetate supplementation restores testicular function by modulating Nrf2/PPAR-γ in high fat diet-induced obesity in Wistar rats by Olaniyi, Kehinde S., Akintayo, Christopher O., Oniyide, Adesola A., Omoaghe, Adams O., Oyeleke, Mosunmola B., Fafure, Adedamola A.

“…Purpose Several studies have established impaired testicular function in obese male population, including the young males with childhood obesity, contributing…”
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Antidiabetic Activity of Elephant Grass (Cenchrus Purpureus (Schumach.) Morrone) via Activation of PI3K/AkT Signaling Pathway, Oxidative Stress Inhibition, and Apoptosis in Wistar Rats by Ojo, Oluwafemi Adeleke, Oni, Abosede Itunuoluwa, Grant, Susan, Amanze, Jennifer, Ojo, Adebola Busola, Taiwo, Odunayo Anthonia, Maimako, Rotdelmwa Filibus, Evbuomwan, Ikponmwosa Owen, Iyobhebhe, Matthew, Nwonuma, Charles Obiora, Osemwegie, Omorefosa, Agboola, Anthonia Oluyemi, Akintayo, Christopher, Asogwa, Nnaemeka Tobechukwu, Aljarba, Nada H, Alkahtani, Saad, Mostafa-Hedeab, Gomaa, Batiha, Gaber El-Saber, Adeyemi, Oluyomi Stephen

“…The management of diabetes over the years has involved the use of herbal plants, which are now attracting interest. We assessed the antidiabetic properties of…”
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Mineralocorticoid receptor blockade attenuates hyperandrogenic metabolic dysregulation in letrozole-induced PCOS rat model by Uhunmwangho, Efosa G., Oniyide, Adesola A., Areloegbe, Stephanie E., Soetan, Olaniyi A., Akintayo, Christopher O., Aturamu, Ayodeji, Olaniyi, Kehinde S.

“…Purpose Polycystic ovarian syndrome (PCOS) is a metabolic syndrome associated with mineralocorticoid receptor (MR) activation, which causes infertility in…”
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Gallic acid and hesperidin elevate neurotransmitters level and protect against oxidative stress, inflammation and apoptosis in aluminum chloride-induced Alzheimer's disease in rats by Ekundayo, Bidemi Emmanuel, Obafemi, Tajudeen Olabisi, Afolabi, Blessing Ariyo, Adewale, Olusola Bolaji, Onasanya, Amos, Osukoya, Olukemi Adetutu, Falode, John Adeolu, Akintayo, Christopher, Adu, Isaac Adekola

“…•GA and hesperidin improved cognition in AlCl3-induced Alzheimer's disease in rats.•Gallic acid and hesperidin improved neurotransmission in AlCl3-induced…”
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High fructose-enriched diet synergistically exacerbates endocrine but not metabolic changes in letrozole-induced polycystic ovarian syndrome in Wistar rats by Akintayo, Christopher O., Johnson, Anjola D., Badejogbin, Olabimpe C., Olaniyi, Kehinde S., Oniyide, Adesola A., Ajadi, Isaac O., Ojewale, Abdulfatai O., Adeyomoye, Olorunsola I., Kayode, Adedeji B.

“…Polycystic Ovarian Syndrome (PCOS) is a multifactorial endocrine-metabolic disorder that highly contributes to the prevalence of infertility globally. The…”
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Adansonia digitata aqueous leaf extract ameliorates dexamethasone-induced testicular injury in male Wistar rats by Joseph Babatunde Dare, Abdulfatai Olakunle Ojewale, Olugbemi Tope Olaniyan, John Adakole Adole, Gloria Enevwo Okotie, Christopher Oloruntoba Akintayo, Ayobami Dare

“…Objective: To evaluate the effects of aqueous leaf extract of Adansonia (A.) digitata L on dexamethasone-induced testicular damage in male Wistar rats…”
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Spilanthes filicaulis (Schumach. & Thonn.) C.D. Adams leaves protects against streptozotocin-induced diabetic nephropathy by Ojo, Oluwafemi Adeleke, Ogunlakin, Akingbolabo Daniel, Akintayo, Christopher Oloruntoba, Olukiran, Olaoluwa Sesan, Adetunji, Juliana Bunmi, Ajayi-Odoko, Omolola Adenike, Ogwa, Theophilus Oghenenyoreme, Molehin, Olorunfemi Raphael, Ojo, Omolara Olajumoke, Mothana, Ramzi A, Alanzi, Abdullah R

“…Diabetic neuropathy (DN) is a complex type of diabetes. The underlying cause of diabetic nephropathy remains unclear and may be due to a variety of…”
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Melatonin ameliorates endocrine dysfunction and defective sperm integrity associated with high‐fat diet‐induced obesity in male Wistar rats by Oladele, Comfort Abisola, Akintayo, Christopher Oloruntoba, Badejogbin, Olabimpe Caroline, Oniyide, Adesola Adedotun, Omoaghe, Adams Olalekan, Agunbiade, Toluwani Bosede, Olaniyi, Kehinde Samuel

“…Obesity (OBS) has been established as a link to male hypogonadism with consequent infertility. Previous studies have shown that melatonin (MEL) modulates…”
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GC-MS chemical profiling, antioxidant, anti-diabetic, and anti-inflammatory activities of ethyl acetate fraction of Spilanthes filicaulis (Schumach. and Thonn.) C.D. Adams leaves: experimental and computational studies by Ojo, Oluwafemi Adeleke, Ogunlakin, Akingbolabo Daniel, Gyebi, Gideon Ampoma, Ayokunle, Damilare IyinKristi, Odugbemi, Adeshina Isaiah, Babatunde, Dare Ezekiel, Ajayi-Odoko, Omolola Adenike, Iyobhebhe, Matthew, Ezea, Samson Chukwuemeka, Akintayo, Christopher Oloruntoba, Ayeleso, Ademola, Ojo, Adebola Busola, Ojo, Omolara Olajumoke

“…This study aimed to investigate the chemical profile of GC-MS, antioxidant, anti-diabetic, and anti-inflammatory activities of the ethyl acetate fraction of…”
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Petiveria alliacea L. extract protects against streptozotocin-induced type-2 diabetes by modulating the cAMP/PKA/CREB/cFOS pathway by Ojo, Oluwafemi Adeleke, Abolade, Olufimihan, Ogunlakin, Akingbolabo Daniel, Akintayo, Christopher Oloruntoba, Olukiran, Olaoluwa Sesan, Odesanmi, Olalekan Elijah, Ajayi-Odoko, Omolola Adenike, Ojo, Adebola Busola, Ajiboye, Basiru Olaitan, Dahunsi, Samuel Olatunde

“…•Methanolic extract of Petiveria alliacea ameliorates early diabetic nephropathy.•Methanolic extract of Petiveria alliacea improves metabolic abnormalities in…”
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Endocrine effects of alcohol and nicotine exposure of alcohol and nicotine exposure in Dams and F1 generation of weaned offspring(s) of female Wistar rats by Akintayo, Christopher, Ojo, Joanna

“…Exposure to nicotine and alcohol in female Wistar rats (Dams) has been indicated in alteration of hormonal status and decreased female fertility success rate…”
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Blockade of mineralocorticoid receptor by low-dose spironolactone rescues hypothalamic-ovarian dysfunction in PCOS experimental rat model by Areleogbe, Stephanie E., Peter, Mmenyene U., Oniyide, Adesola A., Akintayo, Christopher O., Fafure, Adedamola A., Oyeleke, Mosunmola B., Ajadi, Isaac O., Amusa, Oluwatobi A., Ayodeji, Aturamu, Olaniyi, Kehinde S.

“…Studies have shown that women with polycystic ovarian syndrome (PCOS) undergo perturbations of the hypothalamic-pituitary ovarian axis, and frequently suffer…”
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Letrozole and/or Fructose Induced‐Polycystic Ovarian Syndrome in Animal Model by Akintayo, Christopher Oloruntoba, Anjola, Johnson David

“…Abstract only Polycystic ovarian syndrome (PCOS) is one of the most common causes of infertility among women, with about 10% of women affected in the general…”
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PS-B06-1: LOW DOSE SPIRONOLACTONE ALLEVIATES CARDIO-RENAL DISORDER IN EXPERIMENTAL PCOS RAT MODEL BY REDUCTION OF BAX/INFLAMMASOME IMMUNOHISTOCHEMICAL EXPRESSION by Peter, Mmenyene Usen, Areleogbe, Stephanie Esosa, Bashir, Alamin Mohammed, Akintayo, Christopher Oloruntoba, Oniyide, Adesola Adesina, Olaniyi, Kehinde Samuel

“…Objectives: Polycystic ovarian syndrome (PCOS) is the most common endocrine and metabolic disorders among women of reproductive age. It has been associated…”
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