Search Results - "Akinsheye, Idowu"

Fetal hemoglobin in sickle cell anemia by Akinsheye, Idowu, Alsultan, Abdulrahman, Solovieff, Nadia, Ngo, Duyen, Baldwin, Clinton T., Sebastiani, Paola, Chui, David H.K., Steinberg, Martin H.

“…Fetal hemoglobin (HbF) is the major genetic modulator of the hematologic and clinical features of sickle cell disease, an effect mediated by its exclusion from…”
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Sickle cell anemia and vascular dysfunction: The nitric oxide connection by Akinsheye, Idowu, Klings, Elizabeth S.

“…Endothelial dysfunction and impaired nitric oxide bioavailability have been implicated in the pathogenesis of sickle cell anemia. Nitric oxide is a diatomic…”
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Fetal haemoglobin levels and haematological characteristics of compound heterozygotes for haemoglobin S and deletional hereditary persistence of fetal haemoglobin by Ngo, Duyen A., Aygun, Banu, Akinsheye, Idowu, Hankins, Jane S., Bhan, Ishir, Luo, Hong Y., Steinberg, Martin H., Chui, David H. K.

“…Summary Compound heterozygotes for sickle haemoglobin (HbS) and hereditary persistence of fetal haemoglobin (HPFH) have high fetal haemoglobin (HbF) levels but…”
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Age and Sex Determinants of Bone Phenotype in a Transgenic Mouse Model of Sickle Cell Disease by Akinsanmi, Idowu Akinsheye, Lin, Angela, Guldberg, Robert, Platt, Manu, Barabino, Gilda

“…Abstract 3249 Variations in the amino acid sequence of the beta globin gene (HBB) chain can result in the production of variant hemoglobins. Sickle cell anemia…”
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Fetal hemoglobin in sickle cell anemia: Genetic studies of the Arab-Indian haplotype by Ngo, Duyen, Bae, Harold, Steinberg, Martin H., Sebastiani, Paola, Solovieff, Nadia, Baldwin, Clinton T., Melista, Efthymia, Safaya, Surinder, Farrer, Lindsay A., Al-Suliman, Ahmed M., Albuali, Waleed H., Al Bagshi, Muneer H., Naserullah, Zaki, Akinsheye, Idowu, Gallagher, Patrick, Luo, Hong-yuan, Chui, David H.K., Farrell, John J., Al-Ali, Amein K., Alsultan, Abdulrahman

“…Sickle cell anemia is common in the Middle East and India where the HbS gene is sometimes associated with the Arab-Indian (AI) β-globin gene (HBB) cluster…”
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Fetal hemoglobin in sickle cell anemia: Molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans by Akinsheye, Idowu, Solovieff, Nadia, Ngo, Duyen, Malek, Anita, Sebastiani, Paola, Steinberg, Martin H., Chui, David H.K.

“…Fetal hemoglobin (HbF) is a major modifier of disease severity in sickle cell anemia (SCA). Three major HbF quantitative trait loci (QTL) are known: the Xmn I…”
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Fetal Hemoglobin In Sickle Cell Anemia: Molecular Characterization of the High Fetal Hemoglobin Phenotype In African American Patients by Akinsheye, Idowu, Solovieff, Nadia, Malek, Anita, Ngo, Duyen A., Steinberg, Martin H., Chui, David H.K.

“…Abstract 2068 HbF interferes with deoxygenated HbS polymerization, and is a major genetic modifier of sickle cell anemia severity. In this study, we attempted…”
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Characterization of HbF Decline In Compound Heterozygotes for HbS and Deletional Hereditary Persistence of Fetal Hemoglobin by Ngo, Duyen A., Aygun, Banu, Akinsheye, Idowu, Steinberg, Martin H., Hankins, Jane S, Chui, David H.K.

“…Abstract 1626 In gene deletion hereditary persistence of fetal hemoglobin (HPFH) affecting people of African descent, more than 80 kb of DNA is deleted…”
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Co-Inheritance of Delta Thalassemia Might Contribute to the High Fetal Hemoglobin in Sickle Cell Anemia Patients with the Saudi-Indian Haplotype by Alsultan, Abdulrahman, Ngo, Duyen A., Farrell, John J., Ghabbour, Hazem, Akinsheye, Idowu, Al-Ali, Amein, Alsuliman, Ahmed, Al-Baghshi, Muneer, Albuali, Waleed, Alabdulaali, Mohammed, Sebastiani, Paola, Baldwin, Clinton T., Chui, David H.K., Steinberg, Martin H.

“…Abstract 1056 Most sickle cell anemia patients (HBB glu6val homozygotes) indigenous to the Eastern Province of Saudi Arabia have a fetal hemoglobin (HbF) level…”
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Fetal Hemoglobin In Sickle Cell Anemia: Molecular Characterization of Saudi Patients From the Eastern Province by Alsultan, Abdulrahman, Akinsheye, Idowu, Solovieff, Nadia, Ghabbour, Hazem, Ngo, Duyen A., Dworkis, Daniel A, Baldwin, Clinton T., Sebastiani, Paola, Farrer, Lindsay A., Steinberg, Martin H., Chui, David H.K.

“…Abstract 1627 In the Eastern Province of Saudi Arabia, sickle cell anemia (HbSS) is associated with the Saudi Indian (SI) HBB-gene cluster haplotype, high…”
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A functional promoter polymorphism of the δ-globin gene is a specific marker of the Arab-Indian haplotype by Alsultan, Abdulrahman, Ngo, Duyen A., Farrell, John J., Akinsheye, Idowu, Solovieff, Nadia, Ghabbour, Hazem A., Al-Ali, Amein, Alsuliman, Ahmed, Al-Baghshi, Muneer, Albu-Ali, Waleed, Alabdulaali, Mohammed, Baldwin, Clinton T., Farrer, Lindsay A., Luo, Hong, Melista, Efthymia, Safaya, Surinder, Nwaru Jr, Maxwell, Chui, David H.K., Steinberg, Martin H.

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A functional promoter polymorphism of the [delta]-globin gene is a specific marker of the Arab-Indian haplotype by Alsultan, Abdulrahman, Ngo, Duyen A, Farrell, John J, Akinsheye, Idowu, Solovieff, Nadia, Ghabbour, Hazem A, Al-Ali, Amein, Alsuliman, Ahmed, Al-Baghshi, Muneer, Albu-Ali, Waleed, Alabdulaali, Mohammed, Baldwin, Clinton T, Farrer, Lindsay A, Luo, Hong, Melista, Efthymia, Safaya, Surinder, Nwaru, Maxwell, Chui, David HK, Steinberg, Martin H

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Leukemia virus long terminal repeat activates NFκB pathway by a TLR3-dependent mechanism by Abujamra, Ana L., Spanjaard, Remco A., Akinsheye, Idowu, Zhao, Xiansi, Faller, Douglas V., Ghosh, Sajal K.

“…The long terminal repeat (LTR) region of leukemia viruses plays a critical role in tissue tropism and pathogenic potential of the viruses. We have previously…”
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Leukemia virus long terminal repeat activates NFkappaB pathway by a TLR3-dependent mechanism by Abujamra, Ana L, Spanjaard, Remco A, Akinsheye, Idowu, Zhao, Xiansi, Faller, Douglas V, Ghosh, Sajal K

“…The long terminal repeat (LTR) region of leukemia viruses plays a critical role in tissue tropism and pathogenic potential of the viruses. We have previously…”
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Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents by Ghosh, Sajal K., Forman, Lora W., Akinsheye, Idowu, Perrine, Susan P., Faller, Douglas V.

“…Antiviral drugs alone have been unsuccessful in the treatment of Epstein–Barr virus (EBV)-associated malignancies because the virus maintains a latent state of…”
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Short, Discontinuous Exposure to Butyrate Effectively Sensitizes Latently EBV-Infected Lymphoma Cells to Nucleoside Analogue Antiviral Agents by Ghosh, Sajal K., Forman, Lora W., Akinsheye, Idowu, Perrine, Susan P., Faller, Douglas V.

“…Antiviral drugs alone have been unsuccessful in the treatment of Epstein Barr virus (EBV)-associated malignancies because the virus maintains a latent state of…”
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Genetic and molecular regulation of gamma globin gene expression in patients with sickle cell disease by Akinsheye Akinsanmi, Idowu

“…The variability of clinical severity in sickle cell anemia patients has been attributed in part to fetal hemoglobin (HbF) expression. Hereditary persistence of…”
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Genetic and molecular regulation of gamma globin gene expression in patients with sickle cell disease by Akinsheye Akinsanmi, Idowu

“…The variability of clinical severity in sickle cell anemia patients has been attributed in part to fetal hemoglobin (HbF) expression. Hereditary persistence of…”
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