Search Results - "Akinobu Hamadaa"

Population Pharmacokinetics and Adverse Events of Erlotinib in Japanese Patients with Non-small-cell Lung Cancer : Impact of Genetic Polymorphisms in Metabolizing Enzymes and Transporters by Chihiro Endo-Tsukudea, b, c, Ji-ichiro Sasakid, Sho Saekie, Norihiro Iwamotof, Megumi Inabag, Sunao Ushijimag, Hiroto Kishih, Shinji Fujiii, Hiroshi Sembai, Kosuke Kashiwabaraj, Yukari Tsubatak, Mitsuhiro Hayashib, Yuki Kaia, Hideyuki Saitoa, e, Takeshi Isobek, Hirotsugu Kohrogia, Akinobu Hamadaa

“…Determinants of interindividual variability in erlotinib pharmacokinetics (PK) and adverse events remain to be elucidated. This study with 50 Japanese…”
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Association of SLCO1B3 Polymorphism with Intracellular Accumulation of Imatinib in Leukocytes in Patients with Chronic Myeloid Leukemia by Takeru NAMBUa, Akinobu HAMADAa, b, Reiko NAKASHIMAa, Misato YUKIa, Tatsuya KAWAGUCHIc, Hiroaki MITSUYAc, Hideyuki SAITOa

“…Intracellular concentration of imatinib in leukemic cells is thought to affect the clinical efficacy of this drug in patients with chronic myeloid leukemia…”
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P-Glycoprotein Mediates Efflux Transport of Darunavir in Human Intestinal Caco-2 and ABCB1 Gene-Transfected Renal LLC-PK1 Cell Lines by Fujimoto, Hiromi, Higuchi, Maiko, Watanabe, Hiroshi, Koh, Yasuhiro, Ghosh, Arun K., Mitsuya, Hiroaki, Tanoue, Naomi, Hamada, Akinobu, Saito, Hideyuki

“…Darunavir (DRV) is a nonpeptidic protease inhibitor (PI) approved for the treatment of human immunodeficiency virus (HIV) infection. DRV displays potent…”
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High-Performance Liquid Chromatographic Assay for the Determination of Nilotinib in Human Plasma by Yuki, Misato, Yamakawa, Yuji, Uchida, Takashi, Nambu, Takeru, Kawaguchi, Tatsuya, Hamada, Akinobu, Saito, Hideyuki

“…A precise and convenient high-performance liquid chromatography (HPLC) method has been estab-lished to assay nilotinib in human plasma. Chromatographic…”
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