Search Results - "Akinluyi, Elizabeth Toyin"
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Sex differences of microglia in the healthy brain from embryonic development to adulthood and across lifestyle influences
Published in Brain research bulletin (01-10-2023)“…Microglia, the central nervous system innate immune cells, play a critical role in maintaining a homeostatic environment in the brain throughout life. These…”
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Black seed oil reverses chronic antibiotic-mediated depression and social behaviour deficits via modulation of hypothalamic mitochondrial-dependent markers and insulin expression
Published in IBRO neuroscience reports (01-06-2024)“…Chronic antibiotic use has been reported to impair mitochondrial indices, hypothalamus-mediated metabolic function, and amygdala-regulated emotional processes…”
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Thymoquinone protects against lipopolysaccharides‐induced neurodegeneration and Alzheimer‐like model in mice
Published in Alzheimer's & dementia (01-12-2023)“…Background Chronic neuroinflammation has become a cornerstone in the study of neurodegeneration and Alzheimer’s diseases. Thymoquinone is a known…”
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Quercetin abrogates lipopolysaccharide-induced depressive-like symptoms by inhibiting neuroinflammation via microglial NLRP3/NFκB/iNOS signaling pathway
Published in Behavioural brain research (26-07-2023)“…Major depressive disorder is a serious psychiatric illness having serious damaging effect on the quality of life of suffers. Quercetin is a plant flavonoid,…”
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Prolonged ketamine therapy differentially rescues psychobehavioural deficits via modulation of nitro-oxidative stress and oxytocin receptors in the gut-brain-axis of chronically-stressed mice
Published in Psychoneuroendocrinology (01-12-2023)“…Ketamine is an anaesthetic known to have short but rapid-acting anti-depressant effects; however, the neurobehavioural effects of its prolonged use and its…”
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Neurodevelopmental and Neuropsychiatric Disorders
Published in Advances in neurobiology (2024)“…This chapter will focus on microglial involvement in neurodevelopmental and neuropsychiatric disorders, particularly autism spectrum disorder (ASD),…”
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Combined Exposure to Chronic Sleep Deprivation and Caffeine Potentiates Behavioural Deficits by Altering Neurochemical Profile and Synaptophysin Expression in Long-Evans Rats
Published in Neurotoxicity research (01-12-2022)“…Using the Unpredictable Chronic Sleep Deprivation (UCSD) paradigm we developed, the combined effects of chronic sleep deprivation and high caffeine intake on…”
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Ketamine abrogates sensorimotor deficits and cytokine dysregulation in a chronic unpredictable mild stress model of depression
Published in Psychopharmacology (2022)“…Major depressive disorder (MDD) is a serious mental disorder with influence across the functional systems of the body. The pathogenesis of MDD has been known…”
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Lactobacillus plantarum mitigates sexual-reproductive deficits by modulating insulin receptor expression in the hypothalamic-pituitary-testicular axis of hyperinsulinemic mice
Published in Drug metabolism and personalized therapy (18-05-2021)“…Hyperinsulinemia increases the risk factor of diabetes and infertility at a manifold. has several medical significances with limited reports. Hence, this study…”
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