Search Results - "Akinlolu, Olapade Samuel"
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In Silico Investigation of First-Pass Effect on Selected Small Molecule Excipients and Structural Dynamics of P-glycoprotein
Published in Bioinformatics and biology insights (2020)“…In this study, the interaction of selected pharmaceutical excipients on the function of P-glycoprotein (P-gp) and activity of 6 cytochrome P450 (CYP) isoforms…”
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In Silico Toxicological Analysis of Active Compounds Present in Selected Pesticides Sold in South-West Nigeria
Published in Jurnal kesehatan lingkungan (Surabaya. Online) (27-07-2024)“…Introduction: The study investigated the molecular effects of human exposure to commonly used pesticides in Nigeria. Methods: Utilizing computational methods…”
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Ocimum gratissimum L. leaf flavonoid-rich extracts reduced the expression of p53 and VCAM in streptozotocin-induced cardiomyopathy rats
Published in Phytomedicine Plus : International journal of phytotherapy and phytopharmacology (01-05-2024)“…•O. gratissimum leaf flavonoid-rich extracts confer cardioprotective effects in STZ-induced diabetic rats by ameliorating redox imbalance and modulating gene…”
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Nephroprotective Effect of Hibiscus Sabdariffa Leaf Flavonoid Extracts via KIM‑1 and TGF-1β Signaling Pathways in Streptozotocin-Induced Rats
Published in ACS omega (30-04-2024)“…Diabetes-induced kidney damage represents a substantial health hazard, emphasizing the imperative to explore potential therapeutic interventions. This study…”
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