Search Results - "Akin, Ali Tugrul"

Chloroquine Decreased Kir6.2 Immunoreactivity in Chronic Hypoxic Heart by ÜNER, Arda Kaan, KAYMAK, Emin, DOĞANYİĞİT, Züleyha, AKIN, Ali Tuğrul, BAŞARAN, Kemal Erdem, ÖZDAMAR, Saim, YAKAN, Birkan, AKYÜZ, Enes

“…Objective: Experimental and clinical studies indicate that cardiovascular system diseases have the highest mortality rate. One of the major factors underlying…”
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Chloroquine attenuates chronic hypoxia‐induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model by Akin, Ali Tugrul, Kaymak, Emin, Ceylan, Tayfun, Ozturk, Emel, Basaran, Kemal Erdem, Karabulut, Derya, Ozdamar, Saim, Yakan, Birkan

“…Chronic hypoxia negatively affects male fertility by causing pathological changes in male reproductive system. However, underlying mechanisms of this damage…”
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Therapeutic effects of thymoquinone in doxorubicin‐induced hepatotoxicity via oxidative stress, inflammation and apoptosis by Akin, Ali Tuğrul, Öztürk, Emel, Kaymak, Emin, Karabulut, Derya, Yakan, Birkan

“…Cancer is a lethal disease that is characterized by uncontrolled cell division and proliferation, and it results in death in many organisms. Doxorubicin (DOX)…”
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Effects of vitamin B12 on methotrexate hepatotoxicity: evaluation of receptor-interacting protein (RIP) kinase by Karabulut, Derya, Ozturk, Emel, Kuloglu, Nurhan, Akin, Ali Tuğrul, Kaymak, Emin, Yakan, Birkan

“…In the study, we aimed to show the effects of vitamin B12 on the necrosis caused by methotrexate (MTX), a folic acid antagonist. Thirty-two rats were randomly…”
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Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats by Kuloğlu, Nurhan, Karabulut, Derya, Kaymak, Emin, Akin, Ali Tuğrul, Ceylan, Tayfun, Yıldırım, Ayşegül Burçin, Yakan, Birkan

“…Methotrexate (MTX) is a drug with anti-inflammatory and immunosuppressive effects and is also a folic acid antagonist. Our aim in this study is to determine…”
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L-Carnitine ameliorates the liver by regulating alpha-SMA, iNOS, HSP90, HIF-1alpha, and RIP1 expressions of CCL4-toxic rats by Karabulut, Derya, Akin, Ali Tugrul, Unsal, Murat, Lekesizcan, Ayça, Ozyazgan, Tuğçe Merve, Keti, Didem Barlak, Yakan, Birkan, Ekebas, Görkem

“…Carbon tetrachloride (CCL ) toxicity triggers fibrosis, activating various mechanisms within the cell. We aimed to create damage with CCL and investigate the…”
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Protective effect of melatonin on cisplatin-induced liver injury in rats by Kaymak,Emin, Ünsal,Murat, Akın,Ali Tuğrul, Öztürk,Emel, Ceylan,Tayfun, Kuloğlu,Nurhan, Karabulut,Derya, Yakan,Birkan

“…Purpose: We aimed to evaluate the protective effect of melatonin (Mel) on experimental hepatatoxicity induced by cisplatin (Cis). Materials and Methods: A…”
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Investigation of the Therapeutic Effects of Chloroquine in Adriamycin-Induced Hepatotoxicity by Akin, Ali Tuğrul, Kaymak, Emin, Öztürk, Emel, Karabulut, Derya, Kuloğlu, Nurhan, Ceylan, Tayfun, Toluk, Ayşe

“…The aim of this study is to investigate the therapeutic effects of Chloroquine (CLQ) against Adriamycin (ADR) induced hepatotoxicity. ADR is a chemotherapeutic…”
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Electrophysiological, histopathological, and biochemical evaluation of the protective effect of probiotic supplementation against pentylenetetrazole-induced seizures in rats by Aygun, Hatice, Akin, Ali Tuğrul, Kızılaslan, Nildem, Sumbul, Orhan, Karabulut, Derya

“…Research on the relationship between the gut microbiome and epilepsy is accumulating. The present study was conducted to evaluate the effect of probiotic…”
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Thymoquinone attenuates doxorubicin‐cardiotoxicity in rats by Karabulut, Derya, Ozturk, Emel, Kaymak, Emin, Akin, Ali Tuğrul, Yakan, Birkan

“…Contrary to the fact that doxorubicin is a powerful chemotherapeutic agent for the treatment of neoplastic diseases, cardiotoxicity is too important to be…”
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Immunoreactivity of Kir3.1, muscarinic receptors 2 and 3 on the brainstem, vagus nerve and heart tissue under experimental demyelination by Akyuz, Enes, Doğanyiğit, Züleyha, Okan, Asli, Yılmaz, Seher, Uçar, Sümeyye, Akin, Ali Tuğrul

“…Demyelination affects the propogation of neuronal action potential by slowing down the progression. This process results in a neuro-impairment like Multiple…”
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Thymoquinone has a neuroprotective effect against inflammation, oxidative stress, and endoplasmic reticulum stress in the brain cortex, medulla, and hippocampus due to doxorubicin by Kaymak, Emin, Akin, Ali Tuğrul, Öztürk, Emel, Karabulut, Derya, Kuloğlu, Nurhan, Yakan, Birkan

“…Although doxorubicin (DOX) is used in many cancer treatments, it causes neurotoxicity. In this study, the effect of thymoquinone (THQ), a powerful antioxidant,…”
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In vivo Gonadoprotective Effects of Myricetin on Cisplatin- Induced Testicular Damage via Suppression of TLR4/NF-kB Inflammation Pathway and Heat-Shock Response by Akin, Ali Tugrul

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In vivo Gonadoprotective Effects of Myricetin on Cisplatin-Induced Testicular Damage via Suppression of TLR4/NF-[kappa]B Inflammation Pathway and Heat-Shock Response/Efectos Gonadoprotectores in vivo de la Miricetina sobre el Dano Testicular Inducido por Cisplatino Mediante la Supresion de la Via de Inflamacion TLR4/NF-[kappa]B y la Respuesta al Choque Termico by Akin, Ali Tugrul

“…The aim of this study is to reveal the gonadoprotective effects of myricetin (MYC), which has many biological properties, on cisplatin (CP)-induced testicular…”
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Therapeutic effect of thymoquinone on brain damage caused by nonylphenol exposure in rats by Ceylan, Tayfun, Akin, Ali Tuğrul, Karabulut, Derya, Tan, Fazile Cantürk, Taşkiran, Mehmet, Yakan, Birkan

“…Nonylphenol (NP), causes various harmful effects such as cognitive impairment and neurotoxicity. Thymoquinone (TQ), has antioxidant, anti-inflammatory, and…”
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Vitamin B12 suppresses GADD153 , prevents apoptosis and regulates the testicular function in methotrexate treated rat testis by Karabulut, Derya, Öztürk, Emel, Kaymak, Emin, Kuloglu, Nurhan, Akin, Ali Tuğrul, Yakan, Birkan

“…Methotrexate (MTX) is an anti-neoplastic drug that also causes testicular damage. Vitamin B12 (Vit B12) is a water soluble vitamin that is required for normal…”
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Research on the Effects of the Juncus Inflexus Subsp. Inflexus Extract on Low Dose Thioacetamide‐Induced Liver Damage: A Novel Antioxidant by Kaya, Muhittin, KAYMAK, Emin, Akin, Ali Tuğrul, Karabulut, Ezman, Yilmaz, Engin, Kurşat, Murat, Yakan, Birkan

“…In this study was investigated the effects of extract of the Juncus inflexus subsp. inflexus (JI) plant on thioacetimide (TAA)‐induced liver damage. Six…”
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The effect of chloroquine on the TRPC1, TRPC6, and CaSR in the pulmonary artery smooth muscle cells in hypoxia‐induced experimental pulmonary artery hypertension by Kaymak, Emin, Akin, Ali Tuğrul, Tufan, Esra, Başaran, Kemal Erdem, Taheri, Serpil, Özdamar, Saim, Yakan, Birkan

“…Pulmonary arterial hypertension (PAH) is a life‐threatening disease characterized by a constant high pulmonary artery pressure and the remodeling of the…”
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Probiotic supplementation alleviates absence seizures and anxiety- and depression-like behavior in WAG/Rij rat by increasing neurotrophic factors and decreasing proinflammatory cytokines by Aygun, Hatice, Akin, Ali Tugrul, Kızılaslan, Nildem, Sumbul, Orhan, Karabulut, Derya

“…•Probiotics may have anti-seizure and antidepressant/anxiolytic effects in WAG/Rij rat.•SOX2, BDNF and NGF could play roles on the absence epilepsy…”
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Histological evaluation of the effects of rapamycin and 3-methyladenine on cisplatin-induced epididymal injury in rats by Ceylan,Tayfun, Karabulut,Derya, Öztürk,Emel, Akın,Ali Tuğrul, Kaymak,Emin, Yakan,Birkan

“…Purpose: In this study, we aimed to determine the effects of autophagy inhibitor and activator on Cisplatin (Cis)-induced tissue damage. Materials and Methods:…”
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