Search Results - "Akil, S."

Integrative Bioinformatics approaches to therapeutic gene target selection in various cancers for Nitroglycerin by Chinnappan, Jayaprakash, Ramu, Akilandeswari, V., Vidhya Rajalakshmi, S., Akil Kavya

“…Integrative Bioinformatics analysis helps to explore various mechanisms of Nitroglycerin activity in different types of cancers and help predict target genes…”
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Deciphering the complex interplay of obesity, epithelial barrier dysfunction, and tight junction remodeling: Unraveling potential therapeutic avenues by AlMarzooqi, Sara K., Almarzooqi, Fajr, Sadida, Hana Q., Jerobin, Jayakumar, Ahmed, Ikhlak, Abou‐Samra, Abdul‐Badi, Fakhro, Khalid A., Dhawan, Punita, Bhat, Ajaz A., Al‐Shabeeb Akil, Ammira S.

“…Summary Obesity stands as a formidable global health challenge, predisposing individuals to a plethora of chronic illnesses such as cardiovascular disease,…”
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Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells by Subbaraj, Gowtham Kumar, Masoodi, Tariq, Yasam, Santhosh Kumar, Chandrashekar, Kirubhanand, Kulanthaivel, Langeswaran, Shaik, Noor Ahmad, Hashem, Sheema, Alshabeeb Akil, Ammira S., Bhat, Ajaz A.

“…The present study evaluated the efficacy of nano-formulated water-soluble kaempferol and combretastatin alone and combined against the native kaempferol and…”
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Therapeutic implications of signaling pathways and tumor microenvironment interactions in esophageal cancer by Khan, Inamu Rashid, Sadida, Hana Q., Hashem, Sheema, Singh, Mayank, Macha, Muzafar A., Al-Shabeeb Akil, Ammira S., Khurshid, Ibraq, Bhat, Ajaz A.

“…Esophageal cancer (EC) is significantly influenced by the tumor microenvironment (TME) and altered signaling pathways. Downregulating these pathways in EC is…”
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Short‐ and long‐term prognostic performance of exercise ECG and myocardial perfusion SPECT by Kraen, M., Akil, S., Hedén, B., Kjellström, B., Berg, J., Ostenfeld, E., Arheden, H., Carlsson, M., Engblom, H.

“…Background Myocardial perfusion SPECT (MPS) and exercise electrocardiography (Ex‐ECG) results are of prognostic importance for short‐term follow up duration…”
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Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments by Dagar, Gunjan, Gupta, Ashna, Masoodi, Tariq, Nisar, Sabah, Merhi, Maysolun, Hashem, Sheema, Chauhan, Ravi, Dagar, Manisha, Mirza, Sameer, Bagga, Puneet, Kumar, Rakesh, Akil, Ammira S Al-Shabeeb, Macha, Muzafar A, Haris, Mohammad, Uddin, Shahab, Singh, Mayank, Bhat, Ajaz A

“…Traditional cancer treatments use nonspecific drugs and monoclonal antibodies to target tumor cells. Chimeric antigen receptor (CAR)-T cell therapy, however,…”
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Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway by Kuttikrishnan, Shilpa, Ahmad, Fareed, Mateo, Jericha M., Prabhu, Kirti S., El‐Elimat, Tamam, Oberlies, Nicholas H., Pearce, Cedric J., Akil, Ammira S. Alshabeeb, Bhat, Ajaz A., Alali, Feras Q., Uddin, Shahab

“…Multiple myeloma (MM) is a hematologic malignancy associated with malignant plasma cell proliferation in the bone marrow. Despite the available treatments,…”
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Associations between telomere attrition, genetic variants in telomere maintenance genes, and non-small cell lung cancer risk in the Jammu and Kashmir population of North India by Bhat, Gh. Rasool, Jamwal, Rajeshwer Singh, Sethi, Itty, Bhat, Amrita, Shah, Ruchi, Verma, Sonali, Sharma, Minerva, Sadida, Hana Q, Al-Marzooqi, Sara K, Masoodi, Tariq, Mirza, Sameer, Haris, Mohammad, Macha, Muzafar A, Akil, Ammira S. Alshabeeb, Bhat, Ajaz A, Kumar, Rakesh

“…Background Telomeres are repetitive DNA sequences located at the ends of chromosomes, playing a vital role in maintaining chromosomal integrity and stability…”
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Extracellular vesicles as tools and targets in therapy for diseases by Kumar, Mudasir A., Baba, Sadaf K., Sadida, Hana Q., Marzooqi, Sara Al, Jerobin, Jayakumar, Altemani, Faisal H., Algehainy, Naseh, Alanazi, Mohammad A., Abou-Samra, Abdul-Badi, Kumar, Rakesh, Al-Shabeeb Akil, Ammira S., Macha, Muzafar A., Mir, Rashid, Bhat, Ajaz A.

“…Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the extracellular space. They exhibit diverse sizes, contents, and surface…”
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Designing an Optical Router Based on a Multimode-Interference Silicon-On-Insulator Coupler with Tunable Power Transmittance by Akil, Dana S., Othman, Muhammad A., Sherif, Sherif M., Swillam, Mohamed A.

“…The demand on fast and high-bandwidth data transmission is in continuous increase. These demands are highly dependent on optical signal manipulation, including…”
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Network-based identification and prioritization of key transcriptional factors of diabetic kidney disease by Ahmed, Ikhlak, Ziab, Mubarak, Da’as, Sahar, Hasan, Waseem, Jeya, Sujitha P., Aliyev, Elbay, Nisar, Sabah, Bhat, Ajaz A., Fakhro, Khalid Adnan, Alshabeeb Akil, Ammira S.

“…Diabetic nephropathy (DN) is one of the most established microvascular complications of diabetes and a key cause of end-stage renal disease. It is well…”
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Wavelength-scale light concentrator made by direct 3D laser writing of polymer metamaterials by Moughames, J., Jradi, S., Chan, T. M., Akil, S., Battie, Y., Naciri, A. En, Herro, Z., Guenneau, S., Enoch, S., Joly, L., Cousin, J., Bruyant, A.

“…We report on the realization of functional infrared light concentrators based on a thick layer of air-polymer metamaterial with controlled pore size gradients…”
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Epigenetic modifications: Key players in cancer heterogeneity and drug resistance by Sadida, Hana Q, Abdulla, Alanoud, Marzooqi, Sara Al, Hashem, Sheema, Macha, Muzafar A, Akil, Ammira S Al-Shabeeb, Bhat, Ajaz A

“…Cancer heterogeneity and drug resistance remain pivotal obstacles in effective cancer treatment and management. One major contributor to these challenges is…”
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Determination of morphological characteristics of metallic nanoparticles based on modified Maxwell-Garnett fitting of optical responses by Battie, Y., Resano-Garcia, A., En Naciri, A., Akil, S., Chaoui, N.

“…A modified effective medium theory (MEMT) is introduced to determine morphological characteristics and the volume fraction of colloidal metallic nanoparticles…”
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Integrating network analysis with differential expression to uncover therapeutic and prognostic biomarkers in esophageal squamous cell carcinoma by Khurshid, Sana, Usmani, Shahabuddin, Ali, Raiyan, Hamid, Saira, Masoodi, Tariq, Sadida, Hana Q, Ahmed, Ikhlak, Khan, Mohd Shahnawaz, Abeer, Inara, Albalawi, Ibrahim Altedlawi, Bedaiwi, Ruqaiah I, Mir, Rashid, Al-Shabeeb Akil, Ammira S, Bhat, Ajaz A, Macha, Muzafar A

“…Esophageal squamous cell carcinoma (ESCC) accounts for over 90% of all esophageal tumors. However, the molecular mechanism underlying ESCC development and…”
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Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans by Prabhu, Kirti S., Ahmad, Fareed, Kuttikrishnan, Shilpa, Leo, Rari, Ali, Tayyiba Akbar, Izadi, Mahmoud, Mateo, Jericha M., Alam, Majid, Ahmad, Aamir, Al-Shabeeb Akil, Ammira S., Bhat, Ajaz A., Buddenkotte, Joerg, Pourkarimi, Ehsan, Steinhoff, Martin, Uddin, Shahab

“…Non-melanoma skin cancer (NMSC), encompassing basal and squamous cell carcinoma, is the most prevalent cancer in the United States. While surgical removal…”
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Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank by Rossi, Niccolo’, Aliyev, Elbay, Visconti, Alessia, Akil, Ammira S. A., Syed, Najeeb, Aamer, Waleed, Padmajeya, Sujitha S., Falchi, Mario, Fakhro, Khalid A.

“…Studies assessing the impact of amylase genes copy number (CN) on adiposity report conflicting findings in different global populations, likely reflecting the…”
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Long non-coding RNAs modulate tumor microenvironment to promote metastasis: novel avenue for therapeutic intervention by Baba, Sana Khurshid, Baba, Sadaf Khursheed, Mir, Rashid, Elfaki, Imadeldin, Algehainy, Naseh, Ullah, Mohammad Fahad, Barnawi, Jameel, Altemani, Faisal H, Alanazi, Mohammad, Mustafa, Syed Khalid, Masoodi, Tariq, Akil, Ammira S Alshabeeb, Bhat, Ajaz A, Macha, Muzafar A

“…Cancer is a devastating disease and the primary cause of morbidity and mortality worldwide, with cancer metastasis responsible for 90% of cancer-related…”
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Correction: Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments by Dagar, Gunjan, Gupta, Ashna, Masoodi, Tariq, Nisar, Sabah, Merhi, Maysaloun, Hashem, Sheema, Chauhan, Ravi, Dagar, Manisha, Mirza, Sameer, Bagga, Puneet, Kumar, Rakesh, Akil, Ammira S. Al-Shabeeb, Macha, Muzafar A, Haris, Mohammad, Uddin, Shahab, Singh, Mayank, Bhat, Ajaz A

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The link between glycemic control measures and eye microvascular complications in a clinical cohort of type 2 diabetes with microRNA-223-3p signature by Da'as, Sahar I, Ahmed, Ikhlak, Hasan, Waseem H, Abdelrahman, Doua A, Aliyev, Elbay, Nisar, Sabah, Bhat, Ajaz Ahmad, Joglekar, Mugdha V, Hardikar, Anandwardhan A, Fakhro, Khalid A, Akil, Ammira S Al-Shabeeb

“…Type 2 diabetes (T2D) is a critical healthcare challenge and priority in Qatar which is listed amongst the top 10 countries in the world, with its prevalence…”
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