Search Results - "Akiko Hata"

Functions of microRNAs in cardiovascular biology and disease by Hata, Akiko

“…In 1993, lin-4 was discovered as a critical modulator of temporal development in Caenorhabditis elegans and, most notably, as the first in the class of small,…”
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Dysregulation of microRNA biogenesis and gene silencing in cancer by Hata, Akiko, Lieberman, Judy

“…MicroRNAs (miRNAs) are small noncoding RNAs that suppress the abundance of partially complementary mRNAs and inhibit their translation. Each miRNA can regulate…”
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Role of microRNAs in lung development and pulmonary diseases by Sessa, Roberto, Hata, Akiko

“…MicroRNAs (miRNAs) are a class of small noncoding RNA which exert post-transcriptional gene regulation activity by targeting messenger RNAs. miRNAs have been…”
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Micromanaging Vascular Smooth Muscle Cell Differentiation and Phenotypic Modulation by Davis-Dusenbery, Brandi N, Wu, Connie, Hata, Akiko

“…The phenotype of vascular smooth muscle cells (VSMCs) is dynamically regulated in response to various stimuli. In a cellular process known as phenotype…”
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Long-term impact of COVID-19 pandemic on secular changes in metabolic parameters in Japanese workers : Tokushima Cohort Study by Hata, Akiko, Funaki, Makoto

“…Objective : The coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented changes in people’s lifestyles. Since then, our lifestyle has remained…”
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Regulation of MicroRNA Biogenesis: A miRiad of mechanisms by Davis, Brandi N, Hata, Akiko

“…microRNAs are small, non-coding RNAs that influence diverse biological functions through the repression of target genes during normal development and…”
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Smad-mediated regulation of microRNA biosynthesis by Blahna, Matthew T., Hata, Akiko

“…microRNAs (miRNAs) are small non-coding RNAs conserved in metazoans. Depletion of miRNAs results in embryonic lethality, suggesting they are essential for…”
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Effect of Aromatherapy Massage on Quality of Sleep in the Palliative Care Ward: A Randomized Controlled Trial by Kawabata, Noriyuki, Hata, Akiko, Aoki, Tomokazu

“…There is little evidence of the effectiveness of aromatherapy massage in palliative care despite its popularity. This study aimed to investigate the effects of…”
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Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2 by Caruso, Paola, Dunmore, Benjamin J, Schlosser, Kenny, Schoors, Sandra, Dos Santos, Claudia, Perez-Iratxeta, Carol, Lavoie, Jessie R, Zhang, Hui, Long, Lu, Flockton, Amanda R, Frid, Maria G, Upton, Paul D, D'Alessandro, Angelo, Hadinnapola, Charaka, Kiskin, Fedir N, Taha, Mohamad, Hurst, Liam A, Ormiston, Mark L, Hata, Akiko, Stenmark, Kurt R, Carmeliet, Peter, Stewart, Duncan J, Morrell, Nicholas W

“…Pulmonary arterial hypertension (PAH) is characterized by abnormal growth and enhanced glycolysis of pulmonary artery endothelial cells. However, the…”
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Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization by Agnew, Christopher, Ayaz, Pelin, Kashima, Risa, Loving, Hanna S., Ghatpande, Prajakta, Kung, Jennifer E., Underbakke, Eric S., Shan, Yibing, Shaw, David E., Hata, Akiko, Jura, Natalia

“…Upon ligand binding, bone morphogenetic protein (BMP) receptors form active tetrameric complexes, comprised of two type I and two type II receptors, which then…”
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Mechanisms of control of microRNA biogenesis by Davis-Dusenbery, Brandi N, Hata, Akiko

“…MicroRNAs (miRNAs) are a class of ~22 nt non-coding RNAs that control diverse biological functions in animals, plants and unicellular eukaryotes by promoting…”
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Regulation of miRNA biogenesis as an integrated component of growth factor signaling by Blahna, Matthew T, Hata, Akiko

“…Transcriptional control of microRNAs (miRNA) by cell signaling pathways, especially in the context of growth factor regulation, is a widely recognized…”
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Induction of MicroRNA-221 by Platelet-derived Growth Factor Signaling Is Critical for Modulation of Vascular Smooth Muscle Phenotype by Davis, Brandi N., Hilyard, Aaron C., Nguyen, Peter H., Lagna, Giorgio, Hata, Akiko

“…The platelet-derived growth factor (PDGF) signaling pathway is a critical regulator of animal development and homeostasis. Activation of the PDGF pathway leads…”
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Dexmedetomidine Might Exacerbate Acute Kidney Injury, While Midazolam Might Have a Postconditioning Effect: A Rat Model of Lipopolysaccharide-Induced Acute Kidney Injury by Hata, Akiko, Yamamoto, Makiko, Iwasaki, Masae, Morita, Tomonori, Ishikawa, Masashi, Sakamoto, Atsuhiro

“…Background: The preconditioning effects of dexmedetomidine and propofol on septic acute kidney injury (AKI) have been reported, but the postconditioning…”
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The role of microRNAs in cell fate determination of mesenchymal stem cells : balancing adipogenesis and osteogenesis by Kang, H., Incheon National University, Incheon, Republic of Korea, Hata, A., University of California, San Francisco, USA

“…Mesenchymal stem cells (MSCs) are multipotent stem cells capable of differentiating into adipocytes, osteoblasts, or chondrocytes. A mutually inhibitory…”
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Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2 by Wu, Connie, So, Jessica, Davis-Dusenbery, Brandi N., Qi, Hank H., Bloch, Donald B., Shi, Yang, Lagna, Giorgio, Hata, Akiko

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106 by Celona, Barbara, Dollen, John von, Vatsavayai, Sarat C, Kashima, Risa, Johnson, Jeffrey R, Tang, Amy A, Hata, Akiko, Miller, Bruce L, Huang, Eric J, Krogan, Nevan J, Seeley, William W, Black, Brian L

“…Expanded GGGGCC repeats in the first intron of the gene represent the most common cause of familial amyotrophic lateral sclerosis (ALS), but the mechanisms…”
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Combination Therapy with STAT3 Inhibitor Enhances SERCA2a-Induced BMPR2 Expression and Inhibits Pulmonary Arterial Hypertension by Bisserier, Malik, Katz, Michael G, Bueno-Beti, Carlos, Brojakowska, Agnieszka, Zhang, Shihong, Gubara, Sarah, Kohlbrenner, Erik, Fazal, Shahood, Fargnoli, Anthony, Dorfmuller, Peter, Humbert, Marc, Hata, Akiko, Goukassian, David A, Sassi, Yassine, Hadri, Lahouaria

“…Pulmonary arterial hypertension (PAH) is a devastating lung disease characterized by the progressive obstruction of the distal pulmonary arteries (PA)…”
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Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature by Cushing, Leah, Costinean, Stefan, Xu, Wei, Jiang, Zhihua, Madden, Lindsey, Kuang, Pingping, Huang, Jingshu, Weisman, Alexandra, Hata, Akiko, Croce, Carlo M, Lü, Jining

“…Differentiation of lung vascular smooth muscle cells (vSMCs) is tightly regulated during development or in response to challenges in a vessel specific manner…”
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Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome by Kashima, Risa, Roy, Sougata, Ascano, Manuel, Martinez-Cerdeno, Veronica, Ariza-Torres, Jeanelle, Kim, Sunghwan, Louie, Justin, Lu, Yao, Leyton, Patricio, Bloch, Kenneth D, Kornberg, Thomas B, Hagerman, Paul J, Hagerman, Randi, Lagna, Giorgio, Hata, Akiko

“…Epigenetic silencing of fragile X mental retardation 1 (FMR1) causes fragile X syndrome (FXS), a common inherited form of intellectual disability and autism…”
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