Search Results - "Akifumi Nakagawa"
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Antitumor effects of α‐bisabolol against pancreatic cancer
Published in Cancer science (01-12-2011)“…In the present study, we investigated whether α‐bisabolol, a sesquiterpene alcohol present in essential oils derived from a variety of plants, has antitumor…”
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A method for fixing and paraffin embedding tissue to retain the natural fluorescence of reporter proteins
Published in BioTechniques (01-09-2015)“…Green fluorescent protein (GFP) and its derivatives are routinely employed as surrogate markers for gene expression and lineage tracing in genetically…”
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Selective and reversible suppression of intestinal stem cell differentiation by pharmacological inhibition of BET bromodomains
Published in Scientific reports (09-02-2016)“…Absorptive and secretory cells of the small intestine are derived from a single population of Lgr5-expressing stem cells. While key genetic pathways required…”
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A method for fixing and paraffin embedding tissue to retain the natural fluorescence of reporter proteins
Published in BioTechniques (01-01-2017)“…Protocol Summary Here we present an ethanol fixation protocol that allows for the direct visualization of the natural fluorescence of reporter proteins while…”
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Hepatopancreatoduodenectomy with arterial reconstruction for extrahepatic cholangiocarcinoma with celiac axis obstruction: report of a case
Published in Surgery today (Tokyo, Japan) (01-12-2014)“…We report a case of successful right hepatectomy plus pancreatoduodenectomy (Rt-HPD) with arterial reconstruction for extrahepatic bile duct carcinoma with…”
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Hepatobiliary resection with concomitant resection of the inferior vena cava for advanced intrahepatic cholangiocarcinoma: report of a case
Published in Surgery today (Tokyo, Japan) (01-11-2013)“…A 65-year-old female was diagnosed with intrahepatic cholangiocarcinoma involving the inferior vena cava (IVC). The patient underwent right trisectionectomy…”
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Segmental cholangitis impairs hepatic regeneration capacity after partial hepatectomy in rats
Published in HPB (Oxford, England) (01-12-2010)“…Patients with hilar cholangiocarcinoma or hepatolithiasis often develop segmental cholangitis (SC), but it is unclear whether hepatectomy for patients with SC…”
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Solubilization of poorly water‐soluble bioactive molecules in neutral aqueous media by complexation with renatured β‐1,3‐1,6‐glucan nanoparticles
Published in Biopolymers (01-04-2020)“…The design of scaffolds for solubilizing/dispersing poorly water‐soluble bioactive molecules in neutral aqueous media is a major challenge of functional food,…”
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Neoplastic-Stromal Cell Cross-talk Regulates Matrisome Expression in Pancreatic Cancer
Published in Molecular cancer research (01-12-2020)“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by a highly desmoplastic reaction, warranting intense cancer-stroma communication. In this study, we…”
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Regulation of GLI Underlies a Role for BET Bromodomains in Pancreatic Cancer Growth and the Tumor Microenvironment
Published in Clinical cancer research (15-08-2016)“…The initiation, progression, and maintenance of pancreatic ductal adenocarcinoma (PDAC) results from the interplay of genetic and epigenetic events. While the…”
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385 - Targeting Epigenetic Regulation of the Matrisome to Remodel Tumor Collagen in Pancreatic Cancer
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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Targeting Epigenetic Regulation of the Matrisome to Remodel Tumor Collagen in Pancreatic Cancer
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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The efficiency of Nek2 siRNA for liver metastasis of pancreatic cancer
Published in The FASEB journal (01-04-2011)“…Background Nek2 (NIMA‐related kinase 2) is a member of the serine/threonine kinase family, which related to the essential mitotic regulator NIMA. Nek2 is…”
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Dynamics of intrahepatic nitric oxide (NO) using selective NO sensor during hepatic ischemia‐reperfusion in rat liver
Published in The FASEB journal (01-04-2011)“…Objective During major hepatic surgery, repetitive clamping of the hepatoduodenal ligament is necessary to reduce blood loss at the expense of hepatic…”
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Adipose‐derived stem cells transplantation promotes hepatic regeneration following hepatic ischemia‐reperfusion and subsequent hepatectomy in rats
Published in The FASEB journal (01-04-2011)“…Objective Adipose‐derived stem cells (ADSCs) are attractive source of regenerative medicine, because of their high accessibility with low invasiveness. It's…”
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Antitumorous activity of alpha‐bisabolol against pancreatic cancer
Published in The FASEB journal (01-04-2011)“…Objective A selective cytotoxic activity of (−)‐α‐bisabolol has been reported against some human malignant cell lines. We investigated the efficacy of…”
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Lgr5-derived tuft and goblet cells reside in the ampulla and migrate to the pancreas following injury
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-08-2016)“…Intestinal secretory cells play key roles in promoting epithelial repair and immune responses in the small intestine…”
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15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis
Published in American journal of physiology: Gastrointestinal and liver physiology (01-03-2010)“…Acute obstructive cholangitis is a common disease with a high mortality rate. Ligands for peroxisome proliferator-activated receptor-gamma (PPARgamma), such as…”
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