Search Results - "Aki, Anri"

Hypomorphic A20 expression confers susceptibility to psoriasis by Aki, Anri, Nagasaki, Miyuki, Malynn, Barbara Ann, Ma, Averil, Kagari, Takashi

“…Psoriasis is a common inflammatory skin disease that affects approximately 1% of the population worldwide. Tumor necrosis factor-alpha-induced protein 3…”
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Anti‐ORAI1 antibody DS‐2741a, a specific CRAC channel blocker, shows ideal therapeutic profiles for allergic disease via suppression of aberrant T‐cell and mast cell activation by Aki, Anri, Tanaka, Kento, Nagaoka, Nobumi, Kimura, Takako, Baba, Daichi, Onodera, Yoshikuni, Wada, Teiji, Maeda, Hiroaki, Nakanishi, Toshiyuki, Agatsuma, Toshinori, Komai, Tomoaki

“…ORAI1 constitutes the pore‐forming subunit of the calcium release‐activated calcium (CRAC) channel, which is responsible for store‐operated calcium entry into…”
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Discovery of DS42450411 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4-aminopyrimidine derivatives by Fukuda, Takeshi, Ishiyama, Takashi, Katagiri, Takahiro, Ueda, Kenjiro, Muramatsu, Sumie, Hashimoto, Masami, Aki, Anri, Baba, Daichi, Watanabe, Kengo, Tanaka, Naoki

“…[Display omitted] •Hepcidin, a peptide hormone, is a master regulator of systemic iron mobilizations (83 characters).•Hepcidin inhibition could be a strategy…”
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Discovery of DS79182026: A potent orally active hepcidin production inhibitor by Fukuda, Takeshi, Goto, Riki, Kiho, Toshihiro, Ueda, Kenjiro, Muramatsu, Sumie, Hashimoto, Masami, Aki, Anri, Watanabe, Kengo, Tanaka, Naoki

“…[Display omitted] Hepcidin has emerged as the central regulatory molecule of systemic iron homeostasis. Inhibition of hepcidin could be a strategy favorable to…”
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Discovery of DS28120313 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4,6-disubstituted indazole derivatives by Fukuda, Takeshi, Goto, Riki, Kiho, Toshihiro, Ueda, Kenjiro, Muramatsu, Sumie, Hashimoto, Masami, Aki, Anri, Watanabe, Kengo, Tanaka, Naoki

“…[Display omitted] Hepcidin has emerged as the central regulatory molecule in systemic iron homeostasis, and its inhibition could be a favorable strategy for…”
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