Search Results - "Akhurst, T J"

Phase II study of the HSP90-inhibitor BIIB021 in gastrointestinal stromal tumors by Dickson, M.A., Okuno, S.H., Keohan, M.L., Maki, R.G., D'Adamo, D.R., Akhurst, T.J., Antonescu, C.R., Schwartz, G.K.

“…HSP90 inhibition leads to proteosomal degradation of activated KIT and has in vitro activity against gastrointestinal stromal tumors (GIST). BIIB021 is an oral…”
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Using an external gating signal to estimate noise in PET with an emphasis on tracer avid tumors by Schmidtlein, C R, Beattie, B J, Bailey, D L, Akhurst, T J, Wang, W, Gönen, M, Kirov, A S, Humm, J L

“…The purpose of this study is to establish and validate a methodology for estimating the standard deviation of voxels with large activity concentrations within…”
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Use of PET-measured response in involved mediastinal lymph nodes to predict overall survival (OS) in non-small cell lung cancer (NSCLC) patients treated with induction therapy (IT) and surgery by Barnett, S., Plourde, G., Zheng, J., Pietanza, M., Akhurst, T. J., Downey, R. J., Kris, M. G., Shen, R., Rusch, V. W., Park, B. J.

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The association of PET response with complete pathological response (CPR) and residual nodal disease (RND) after induction chemoradiotherapy (CRT) and resection of esophageal cancer: A review of 493 cases by Barnett, S. A., Rizk, N. P., Adusumilli, P. S., Park, B. J., Bains, M. S., Flores, R. M., Goodman, K. A., Ilson, D. H., Akhurst, T. J., Rusch, V. W.

“…Abstract only 4552 Background: RND and lack of CPR of the primary tumor correlate with poor survival after induction CRT and resection of esophageal cancer…”
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Response to neoadjuvant chemotherapy as measured by PET predicts outcome after liver resection for colorectal metastases by Akhurst, T. J., Gonen, M., Tuorto, S., Schwartz, L., Brody, L., Larson, S. M., Fong, Y.

“…Abstract only 3056 Background: Patients with hepatic colorectal metastases are often treated with neoadjuvant chemotherapy prior to liver resection. FDG PET is…”
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Novel noninvasive measurement of total tumor glycolysis by PET predicts survival after complete surgical resection of NSCLC by Akhurst, T. J., Downey, R. J., Gonen, M., Vincent, A., Rusch, V. W., Larson, S. M.

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Novel noninvasive measurement of total tumor glycolysis by PET predicts survival after complete surgical resection of NSCLC by Akhurst, T. J., Downey, R. J., Gonen, M., Vincent, A., Rusch, V. W., Larson, S. M.

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Thiopental and propofol affect different regions of the brain at similar pharmacologic effects by VESELIS, Robert A, FESHCHENKO, Vladimir A, REINSEL, Ruth A, DNISTRIAN, Ann M, BEATTIE, Bradley, AKHURST, Timothy J

“…Propofol has a greater amnesic effect than thiopental. In this study we tested whether different brain regions were affected by propofol and thiopental at…”
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Propofol and thiopental do not interfere with regional cerebral blood flow response at sedative concentrations by VESELIS, Robert A, FESHCHENKO, Vladimir A, REINSEL, Ruth A, BEATTIE, Bradley, AKHURST, Timothy J

“…Anesthetics may affect the regional cerebral blood flow (rCBF) response associated with increased brain activity in humans. rCBF was measured as auditory…”
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Use of positron emission tomography to target prostate cancer gene therapy by oncolytic herpes simplex virus by Mullerad, Michael, Eisenberg, David P, Akhurst, Timothy J, Adusumilli, Prasad S, Riedl, Christopher C, Bhargava, Amit, Gonen, Mithat, Finn, Ronald, Scardino, Peter T, Fong, Yuman

“…Herpes simplex virus (HSV) oncolytic gene therapy is a promising treatment modality against cancer. We have demonstrated that androgen-induced cellular changes…”
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