Search Results - "Akhter, Mohammed P."

Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice by Jackson, Erica, Lara-Castillo, Nuria, Akhter, Mohammed P., Dallas, Mark, Scott, JoAnna M., Ganesh, Thiagarajan, Johnson, Mark L.

“…Estrogen levels decline in both sexes with age, but more dramatically in females. Activation of the Wnt/β-catenin signaling pathway is central to the…”
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A pilot study on the nanoscale properties of bone tissue near lacunae in fracturing women by Qian, Wen, Schmidt, Roman, Turner, Joseph A., Bare, Sue P., Lappe, Joan M., Recker, Robert R., Akhter, Mohammed P.

“…The goal of this study is to investigate the causes of osteoporosis-related skeletal fragility in postmenopausal women. We hypothesize that bone fragility in…”
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Chronic Pancreatic Inflammation Induced by Environmental Tobacco Smoke Inhalation in Rats by WITTEL, Uwe A, PANDEY, Krishan K, ANDRIANIFAHANANA, Mahefatiana, JOHANSSON, Sonny L, CULLEN, Diane M, AKHTER, Mohammed P, BRAND, Randall E, PROKOPCZYK, Bogdain, BATRA, Surinder K

“…Despite a strong epidemiological association between cigarette smoking and pancreatic diseases, such as pancreatic cancer and chronic pancreatitis, the effects…”
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Osteoclast Deficiency Results in Disorganized Matrix, Reduced Mineralization, and Abnormal Osteoblast Behavior in Developing Bone by Dai, Xu‐Ming, Zong, Xiao‐Hua, Akhter, Mohammed P, Stanley, E Richard

“…Studies of the influence of the osteoclast on bone development, in particular on mineralization and the formation of the highly organized lamellar architecture…”
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N-acetylcysteine increases the frequency of bone marrow pro-B/pre-B cells, but does not reverse cigarette smoking-induced loss of this subset by Palmer, Victoria L, Kassmeier, Michele D, Willcockson, James, Akhter, Mohammed P, Cullen, Diane M, Swanson, Patrick C

“…We previously showed that mice exposed to cigarette smoke for three weeks exhibit loss of bone marrow B cells at the Pro-B-to-pre-B cell transition, but the…”
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Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain by Nandi, Sayan, Akhter, Mohammed P., Seifert, Mark F., Dai, Xu-Ming, Stanley, E. Richard

“…The primary macrophage growth factor, colony-stimulating factor-1 (CSF-1), is homodimeric and exists in 3 biologically active isoforms: a membrane-spanning,…”
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Nonenzymatic Glycation and Degree of Mineralization Are Higher in Bone From Fractured Patients With Type 1 Diabetes Mellitus by Farlay, Delphine, Armas, Laura AG, Gineyts, Evelyne, Akhter, Mohammed P, Recker, Robert R, Boivin, Georges

“…ABSTRACT Low‐energy fractures are frequent complications in type 1 diabetes mellitus patients (T1DM). Modifications of bone intrinsic composition might be a…”
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Intrinsic material properties of cortical bone by Lopez Franco, Gloria E, Blank, Robert D, Akhter, Mohammed P

“…The G171V mutation (high bone mass, HBM) is autosomal dominant and is responsible for high bone mass in humans. Transgenic HBM mice in which the human LRP5…”
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Trabecular bone score and transilial bone trabecular histomorphometry in type 1 diabetes and healthy controls by Thangavelu, Thiyagarajan, Silverman, Emily, Akhter, Mohammed P., Lyden, Elizabeth, Recker, Robert R., Graeff-Armas, Laura A.

“…Patients with type 1 Diabetes Mellitus (T1DM) have an increased risk of fracture. Little is known about the microarchitecture of trabecular bone in T1DM, which…”
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Combining fructooligosaccharide and dried plum has the greatest effect on restoring bone mineral density among select functional foods and bioactive compounds by Arjmandi, Bahram H, Johnson, Catherine D, Campbell, Sara C, Hooshmand, Shirin, Chai, Sheau C, Akhter, Mohammed P

“…Functional foods and/or their bioactive compounds playing a role in improving skeletal health have received considerable attention. The objective of the…”
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Effects of glucocorticoid treatment on bone strength by Manolides, Andrew S, Cullen, Diane M, Akhter, Mohammed P

“…Glucocorticoids (GCs) are prescribed for the treatment of several diseases, but their long-term use causes osteoporosis. Current research suggests that GCs…”
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Enzymatic and Non-enzymatic Collagen Cross-Links and Fracture Occurrence in Type 1 Diabetes Patients by Paschalis, Eleftherios P., Gamsjaeger, Sonja, Graeff-Armas, Laura A., Bare, Sue P., Recker, Robert R., Akhter, Mohammed P.

“…Increased fracture risk in type 1 diabetes (T1D) patients is not fully captured by bone mineral density (BMD) by DXA. Advanced glycation end-products (AGEs)…”
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Bone intrinsic material and compositional properties in postmenopausal women diagnosed with long-term Type-1 diabetes by Qian, Wen, Gamsjaeger, Sonja, Paschalis, Eleftherios P., Graeff-Armas, Laura A., Bare, Sue P., Turner, Joseph A., Lappe, Joan M., Recker, Robert R., Akhter, Mohammed P.

“…The incidence of diabetes mellitus and the associated complications are growing worldwide, affecting the patients' quality of life and exerting a considerable…”
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Effects of Vitamin E on Bone Biomechanical and Histomorphometric Parameters in Ovariectomized Rats by Feresin, Rafaela G., Johnson, Sarah A., Elam, Marcus L., Kim, Jeong-Su, Khalil, Dania A., Lucas, Edralin A., Smith, Brenda J., Payton, Mark E., Akhter, Mohammed P., Arjmandi, Bahram H.

“…The present study examined the dose-dependent effect of vitamin E in reversing bone loss in ovariectomized (Ovx) rats. Sprague-Dawley rats were either…”
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Bone histomorphometry in transiliac biopsies from 48 normal, healthy men by Recker, Robert R., Akhter, Mohammed P., Lappe, Joan M., Watson, Patrice

“…Investigators and clinicians use bone histomorphometry data from iliac bone biopsies to study bone abnormalities in diseased patients, and to understand the…”
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Bone-targeting liposome formulation of Salvianic acid A accelerates the healing of delayed fracture Union in Mice by Liu, Yanzhi, Jia, Zhenshan, Akhter, Mohammed P., Gao, Xiang, Wang, Xiaobei, Wang, Xiaoyan, Zhao, Gang, Wei, Xin, Zhou, You, Wang, Xiuli, Hartman, Curtis W., Fehringer, Edward V., Cui, Liao, Wang, Dong

“…Delayed fracture union is a significant clinical challenge in orthopedic practice. There are few non-surgical therapeutic options for this pathology. To…”
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Trabecular bone histomorphometry in humans with Type 1 Diabetes Mellitus by Armas, Laura A.G, Akhter, Mohammed P, Drincic, Andjela, Recker, Robert R

“…Abstract Patients with Type 1 Diabetes Mellitus (DM) have markedly increased risk of fracture, but little is known about abnormalities in bone…”
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Effect of Macroanatomic Bone Type and Estrogen Loss on Osteocyte Lacunar Properties in Healthy Adult Women by Akhter, Mohammed P., Kimmel, D. B., Lappe, J. M., Recker, R. R.

“…This is the first study to examine clinical human bone specimens by three-dimensional imaging to characterize osteocyte lacunar properties as a function of…”
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Altered collagen chemical compositional structure in osteopenic women with past fractures: A case-control Raman spectroscopic study by Mandair, Gurjit S., Akhter, Mohammed P., Esmonde-White, Francis W.L., Lappe, Joan M., Bare, Susan P., Lloyd, William R., Long, Jason P., Lopez, Jessica, Kozloff, Kenneth M., Recker, Robert R., Morris, Michael D.

“…Incidences of low-trauma fractures among osteopenic women may be related to changes in bone quality. In this blinded, prospective-controlled study,…”
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Oncologic doses of zoledronic acid induce osteonecrosis of the jaw-like lesions in rice rats (Oryzomys palustris) with periodontitis by Aguirre, J Ignacio, Akhter, Mohammed P, Kimmel, Donald B, Pingel, Jennifer E, Williams, Alyssa, Jorgensen, Marda, Kesavalu, Lakshmyya, Wronski, Thomas J

“…Though osteonecrosis of the jaw (ONJ) is temporally‐associated with the use of nitrogen‐containing bisphosphonates (N‐BPs), a cause‐and‐effect relationship has…”
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