Search Results - "Akhter, Ariz"

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    A bioclinical prognostic model using MYC and BCL2 predicts outcome in relapsed/refractory diffuse large B-cell lymphoma by Bosch, Mark, Akhter, Ariz, Chen, Bingshu E, Mansoor, Adnan, Lebrun, David, Good, David, Crump, Michael, Shepherd, Lois, Scott, David W, Stewart, Douglas A

    Published in Haematologica (Roma) (01-02-2018)
    “…The objective of this study was to create a bioclinical model, based on clinical and molecular predictors of event-free and overall survival for…”
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    The KIR-HLA-CD16a Immunogenetic Profile Influences NK Cell-Mediated ADCC and Response to Rituximab Therapy in B-Cell Lymphomas by Khanolkar, Rutvij A., Akhter, Ariz, Storek, Jan, Khan, Faisal

    Published in Blood (02-11-2023)
    “…Rituximab-based chemoimmunotherapy (R-CHOP) is the standard of care in most B-cell lymphomas, however there is marked interpatient heterogeneity in treatment…”
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    Unraveling the molecular landscape: a comparative analysis of PI3K and MAPK signaling pathways in plasmablastic lymphoma and diffuse large B-cell lymphoma with therapeutic implications by Mansoor, Adnan, Akhter, Ariz, Kamran, Hamza, Minoo, Parham, Stewart, Douglas

    Published in Human pathology (01-11-2023)
    “…Plasmablastic lymphoma (PBL) is a rare and aggressive subtype of non-Hodgkin lymphoma that shares features with diffuse large B-cell lymphoma (DLBCL). While…”
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    Acute Myeloid Leukaemia in Elderly: Expression Analysis of DNA Damage Response (DDR) and Anti-Apoptosis Genes Identify Novel Targets for Potential “Synergistic Lethality” by Rizwan, Hassan, Kamran, Hamza, Akhter, Ariz, Elyamany, Ghaleb, Shahbani-Rad, Meer-Taher, Mansoor, Adnan

    Published in Blood (05-11-2020)
    “…Background: Genetic instability and heterogeneity are fundamental to AML biology and pivotal to its prognosis. Acute myeloid leukaemia (AML) is most frequent…”
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    Plasmablastic Lymphoma: Synergism between Wnt/B-Catenin and the RAS S ignalling Molecules May Identify Potential Targets for Therapy by Kamran, Hamza, Akhter, Ariz, Rizwan, Hassan, Shahbani-Rad, Meer-Taher, Elyamany, Ghaleb, Stewart, Douglas A., Mansoor, Adnan

    Published in Blood (05-11-2020)
    “…Background:Plasmablastic lymphoma (PBL), is a rare aggressive B-cell lymphoma that shares many overlapping characteristics with activated B-cell type diffuse…”
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    Plasmablastic Lymphoma: Synergism betweenWnt/B-Cateninand theRAS Signalling Molecules May Identify Potential Targets for Therapy by Kamran, Hamza, Akhter, Ariz, Rizwan, Hassan, Shahbani-Rad, Meer-Taher, Elyamany, Ghaleb, Stewart, Douglas A., Mansoor, Adnan

    Published in Blood (05-11-2020)
    “…Background:Plasmablastic lymphoma (PBL), is a rare aggressive B-cell lymphoma that shares many overlapping characteristics with activated B-cell type diffuse…”
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    Journal Article
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    Identification of Potential Therapeutic Targets for Plasmablastic Lymphoma Through Gene Expression Analysis: Insights into RAS and Wnt Signaling Pathways by Mansoor, Adnan, Kamran, Hamza, Akhter, Ariz, Seno, Rommel, Torlakovic, Emina E., Roshan, Tariq Mahmood, Shabani-Rad, Meer-Taher, Elyamany, Ghaleb, Minoo, Parham, Stewart, Douglas

    Published in Modern pathology (01-08-2023)
    “…Plasmablastic lymphoma (PBL) is a rare and aggressive B-cell lymphoma with overlapping characteristics with diffuse large B-cell lymphoma (DLBCL) and multiple…”
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    Journal Article
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    Primary testicular lymphoma demonstrates overexpression of the Wilms tumor 1 gene and different mRNA and miRNA expression profiles compared to nodal diffuse large B‐cell lymphoma by Mansoor, Adnan, Akhter, Ariz, Shabani‐Rad, Meer‐Taher, Deschenes, Jean, Yilmaz, Asli, Trpkov, Kiril, Stewart, Douglas

    Published in Hematological oncology (01-12-2023)
    “…Diffuse large B‐cell lymphoma (DLBCL) shows a high degree of clinical and biological heterogeneity. Primary testicular lymphoma (PTL) is an extranodal variant…”
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    Differential Expression of Immunity Related Genes and Early Prediction of Severe Graft Versus Host Disease after Allogeneic Hematopoietic Cell Transplantation by Dharmani-Khan, Poonam, Faridi, Rehan Mujeeb, Akhter, Ariz, Kalra, Amit, Storek, Jan, Khan, Faisal M

    Published in Blood (02-12-2016)
    “…Background: Allogeneic hematopoietic cell transplantation (HCT) is curative for hematological malignancies. However, Graft versus host disease (GVHD) is the…”
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    Differential Gene Expression Using RNA Sequencing Between Elderly Acute Myeloid Leukemia (AML) Patients with Long Versus Short-Term Survival by Trottier, Amy M, Mansoor, Adnan, Owen, Carolyn J., Akhter, Ariz, Mahe, Etienne, Geddes, Michelle

    Published in Blood (02-12-2016)
    “…Introduction Advances in genetic sequencing have shed light on the biological underpinnings of AML, however, the vast majority of previous work has focused on…”
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    Expression of “DNA damage response” pathway genes in diffuse large B‐cell lymphoma: The potential for exploiting synthetic lethality by Mansoor, Adnan, Kamran, Hamza, Rizwan, Hassan, Akhter, Ariz, Roshan, Tariq Mahmood, Shabani‐Rad, Meer‐Taher, Bavi, Prashant, Stewart, Douglas

    Published in Hematological oncology (01-01-2024)
    “…Diffuse large B‐cell lymphoma (DLBCL) and follicular lymphoma (FL) are two of the most prevalent non‐Hodgkin's lymphoma subtypes. Despite advances, treatment…”
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    CD10-positive mantle cell lymphoma: biologically distinct entity or an aberrant immunophenotype? Insight, through gene expression profile in a unique case series by Akhter, Ariz, Mahe, Etienne, Street, Lesley, Pournazari, Payam, Perizzolo, Marco, Shabani-Rad, Meer-Taher, Stewart, Douglas A, Mansoor, Adnan

    Published in Journal of clinical pathology (01-10-2015)
    “…Mantle cell lymphoma (MCL) is an aggressive disease with genetic heterogeneity and discrete clinical subtypes. MCL is rarely CD10 positive. These cases raise…”
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    OR11 Low content of activating killer immunoglobulin-like receptors predispose to hematological malignancies by Akhter, Ariz, Faridi, Rehan, Lewis, Victor, Storek, Jan, Berka, Noureddine, Khan, Faisal

    Published in Human immunology (01-09-2017)
    “…Natural killer (NK) cells are critical in surveillance against viral infections and malignancies. Central to the regulation of NK cells is incredible diversity…”
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    P027 FCGRIIIA gene variant influences differential rituximab mediated NK cell response against different B-cell lymphoma targets by Akhter, Ariz, Faridi, Rehan M., Tripathi, Gaurav, Dharmani-Khan, Poonam, Stewart, Douglas, Mansoor, Adnan, Khan, Faisal

    Published in Human immunology (01-09-2017)
    “…Rituximab based therapy is the frontline treatment for aggressive B-cell malignancies (Diffuse large B cell lymphoma, DLBCL, Mantle Cell lymphoma, MCL and…”
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    Journal Article