Search Results - "Akhmedov, Alexandre T."
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Human POMP75 is identified as the pro-oncoprotein TLS/FUS : both POMp75 and POMp100 DNA homologous pairing activities are associated to cell proliferation
Published in Oncogene (05-08-1999)“…We have previously developed an assay to measure DNA homologous pairing activities in crude extracts: The POM blot. In mammalian nuclear extracts, we detected…”
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Human 75-kDa DNA-pairing Protein Is Identical to the Pro-oncoprotein TLS/FUS and Is Able to Promote D-loop Formation
Published in The Journal of biological chemistry (26-11-1999)“…Homologous recombination plays a fundamental role in DNA double-strand break repair. Previously, we detected two mammalian nuclear proteins of 100 and 75 kDa…”
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A B-cell-specific DNA Recombination Complex
Published in The Journal of biological chemistry (03-07-1998)“…We have purified and biochemically characterized a multiprotein complex designated SWAP. In a DNA transfer assay, SWAP preferentially recombines (âswapsâ)…”
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Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion
Published in Nucleic acids research (15-08-2000)“…Proteins promoting homologous pairing could be involved in various fundamental biological processes. Previously we detected two mammalian nuclear proteins of…”
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Structural Maintenance of Chromosomes Protein C-terminal Domains Bind Preferentially to DNA with Secondary Structure
Published in The Journal of biological chemistry (11-09-1998)“…Structural maintenance of chromosomes (SMC) proteins interact with DNA in chromosome condensation, sister chromatid cohesion, DNA recombination, and gene…”
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Mammalian SMC3 C-terminal and Coiled-coil Protein Domains Specifically Bind Palindromic DNA, Do Not Block DNA Ends, and Prevent DNA Bending
Published in The Journal of biological chemistry (31-12-1999)“…The C-terminal domains of yeast structural maintenance of chromosomes (SMC) proteins were previously shown to bind double-stranded DNA, which generated the…”
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Characterization of Two Nuclear Mammalian Homologous DNA-Pairing Activities that do not Require Associated Exonuclease Activity
Published in Proceedings of the National Academy of Sciences - PNAS (28-02-1995)“…We have developed an assay to study homologous DNA-pairing activities in mammalian nuclear extracts. This assay is derived from the POM blot assay, described…”
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SMC proteins constitute two subunits of the mammalian recombination complex RC‐1
Published in The EMBO journal (01-08-1996)“…Recombination protein complex RC‐1, purified from calf thymus nuclear extracts, catalyzes cell‐free DNA strand transfer and repair of gaps and deletions…”
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Partial purification and characterization of two types of homologous DNA pairing activity from rat testis nuclei
Published in Biochimica et biophysica acta (01-03-1996)“…We describe the partial purification and characterization of two different types of homologous DNA pairing activity from rat testis nuclear extracts. The…”
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