The diffusion-tensor imaging reveals alterations in water diffusion parameters in acute pediatric concussion

Wide-spread visualization methods which are computed tomography (CT) and magnetic resonance imaging (MRI) are not sensitive to mild traumatic brain injury (mTBI). However, mTBI may cause changes of cerebral microstructure that could be found using diffusion-tensor imaging. The aim of this study is t...

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Bibliographic Details
Published in:	Acta neurologica Belgica Vol. 121; no. 6; pp. 1463 - 1468
Main Authors:	Vasiukova, O. R., Akhlebinina, M. I., Manzhurtsev, A. V., Menshchikov, P. E., Ublinskiy, M. V., Yakovlev, A. N., Akhadov, T. A., Semenova, N. A.
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01-12-2021
Subjects:	Adolescent Anisotropy Biomedical and Life Sciences Biomedicine Brain Concussion - diagnostic imaging Brain Concussion - metabolism Child Corpus Callosum - diagnostic imaging Corpus Callosum - metabolism Diffusion Diffusion Tensor Imaging - methods Diffusion Tensor Imaging - trends Female Humans Male Medicine/Public Health Neurology Neuroradiology Neurosciences Original Article Thalamus - diagnostic imaging Thalamus - metabolism Water - metabolism Fractional anisotropy (FA) Apparent diffusion coefficient (ADC) Thalamus Mild traumatic brain injury (mTBI) Corpus callosum Diffusion-tensor imaging (DTI)
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Summary:	Wide-spread visualization methods which are computed tomography (CT) and magnetic resonance imaging (MRI) are not sensitive to mild traumatic brain injury (mTBI). However, mTBI may cause changes of cerebral microstructure that could be found using diffusion-tensor imaging. The aim of this study is to reveal the impact of acute mTBI (no more than 3 days after trauma) on diffusion parameters in corpus callosum, corticospinal tract, and thalamus in children (aged 14–18). Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were analyzed. Significant increase in FA and decrease in ADC were observed in thalamus. The trend to an increase in FA is observed in corpus callosum.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0300-9009 2240-2993
DOI:	10.1007/s13760-020-01347-w