Search Results - "Akhirunnesa, Mily"
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1
Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial
Published in PloS one (22-09-2015)“…Development of new tuberculosis (TB) drugs and alternative treatment strategies are urgently required to control the global spread of TB. Previous results have…”
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Journal Article -
2
Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial
Published in BMC infectious diseases (10-05-2012)“…Treatment of shigellosis in rabbits with butyrate reduces clinical severity and counteracts the downregulation of cathelicidin (CAP-18) in the large intestinal…”
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Journal Article -
3
Slow radiological improvement and persistent low-grade inflammation after chemotherapy in tuberculosis patients with type 2 diabetes
Published in BMC infectious diseases (07-12-2020)“…Diabetes mellitus type 2 (DM) may impede immune responses in tuberculosis (TB) and thus contribute to enhanced disease severity. In this study, we aimed to…”
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Journal Article -
4
Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D3 as host directed therapy
Published in BMC infectious diseases (04-07-2018)“…We have previously shown that 8 weeks' treatment with phenylbutyrate (PBA) (500mgx2/day) with or without vitamin D.sub.3 (vitD.sub.3) (5000 IU/day) as…”
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Journal Article -
5
Ciprofloxacin Affects Host Cells by Suppressing Expression of the Endogenous Antimicrobial Peptides Cathelicidins and Beta-Defensin-3 in Colon Epithelia
Published in Antibiotics (Basel) (25-07-2014)“…Antibiotics exert several effects on host cells including regulation of immune components. Antimicrobial peptides (AMPs), e.g., cathelicidins and defensins…”
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Journal Article -
6
Immunopathogenesis in Pulmonary Tuberculosis : Impact of Immunomodulation and Diabetes Co-Morbidity
Published 01-01-2021“…Even in the 21st century, tuberculosis (TB) remains a major global health threat, primarily due to the emergence of antibiotic resistance. Presence of…”
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Dissertation -
7
Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection
Published in Journal of visualized experiments (18-09-2020)“…Human macrophages are primary host cells of intracellular Mycobacterium tuberculosis (Mtb) infection and thus have a central role in immune control of…”
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Journal Article -
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Functional Antibodies and Innate Immune Responses to WRSS1, a Live Oral Shigella sonnei Vaccine Candidate, in Bangladeshi Adults and Children
Published in The Journal of infectious diseases (20-12-2021)“…Abstract Background We demonstrated in a randomized placebo-controlled trial that WRSS1, a live oral Shigella sonnei vaccine candidate, is safe in Bangladeshi…”
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Journal Article -
9
Immunosuppressive Features of the Microenvironment in Lymph Nodes Granulomas from Tuberculosis and HIV–Co-Infected Patients
Published in The American journal of pathology (01-04-2022)“…Tuberculosis (TB) and HIV co-infection claims many lives every year. This study assessed immune responses in Mycobacterium tuberculosis–infected lymph node…”
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Journal Article -
10
Identity of virus-specific and cross-reactive T cell memory to mpox
Published in JOURNAL OF IMMUNOLOGY (2023)“…Abstract The unprecedented spread of mpox (previously known as monkeypox) in several countries worldwide has led the WHO to declare the mpox outbreak a global…”
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Journal Article Conference Proceeding -
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Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox
Published in Cell host & microbe (14-06-2023)“…Mpox represents a persistent health concern with varying disease severity. Reinfections with mpox virus (MPXV) are rare, possibly indicating effective memory…”
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Journal Article -
12
Immune cell landscape in symptomatic and asymptomatic SARS-CoV-2 infected adults and children in urban Dhaka, Bangladesh
Published in Immunobiology (1979) (01-03-2023)“…•SARS-CoV-2 seropositive adults and children had reduced proportion of CD3+ T cells than seronegative adults and children.•Seropositive children had higher CD4…”
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Journal Article -
13
In utero arsenic exposure is associated with impaired thymic function in newborns possibly via oxidative stress and apoptosis
Published in Toxicological sciences (01-10-2012)“…Prenatal arsenic exposure is associated with increased infant morbidity and reduced thymus size, indicating arsenic-related developmental immunotoxicity. We…”
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Journal Article -
14
Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D 3 as host directed therapy
Published in BMC infectious diseases (04-07-2018)“…We have previously shown that 8 weeks' treatment with phenylbutyrate (PBA) (500mgx2/day) with or without vitamin D (vitD ) (5000 IU/day) as host-directed…”
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Journal Article -
15
Prenatal high-dose vitamin D3 supplementation has balanced effects on cord blood Th1 and Th2 responses
Published in Nutrition journal (09-08-2016)“…Antenatal vitamin D3 (vitD3) supplementation significantly increases maternal and neonatal 25-hydroxyvitamin D3 (25(OH)D3) concentration, yet the effect of an…”
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Journal Article -
16
Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis
Published in BMC pulmonary medicine (16-04-2013)“…We earlier showed that 4-phenylbutyrate (PB) can induce cathelicidin LL-37 expression synergistically with 1,25-dihydroxyvitamin D3 in a lung epithelial cell…”
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Journal Article -
17
Prenatal vitamin D sub(3) supplementation suppresses LL-37 peptide expression in ex vivo activated neonatal macrophages but not their killing capacity
Published in British journal of nutrition (28-09-2014)“…Vitamin D has regulatory effects on innate immunity. In the present study, we aimed to assess the effect of prenatal vitamin D sub(3) (vitD sub(3))…”
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Journal Article -
18
MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles
Published in Science immunology (06-09-2024)“…Mucosal-associated invariant T (MAIT) cells are unconventional T cells that recognize microbial riboflavin pathway metabolites presented by evolutionarily…”
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Journal Article -
19
Prenatal vitamin D3 supplementation suppresses LL-37 peptide expression in ex vivo activated neonatal macrophages but not their killing capacity
Published in British journal of nutrition (28-09-2014)“…Vitamin D has regulatory effects on innate immunity. In the present study, we aimed to assess the effect of prenatal vitamin D3 (vitD3) supplementation on…”
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Journal Article -
20
Prenatal vitamin D 3 supplementation suppresses LL-37 peptide expression in ex vivo activated neonatal macrophages but not their killing capacity
Published in British journal of nutrition (28-09-2014)“…Vitamin D has regulatory effects on innate immunity. In the present study, we aimed to assess the effect of prenatal vitamin D 3 (vitD 3 ) supplementation on…”
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Journal Article