Ultrasound-guided transversus abdominis plane block in patients undergoing open inguinal hernia repair: 0.125% bupivacaine provides similar analgesic effect compared to 0.25% bupivacaine

Abstract Study objective To evaluate the effectiveness of 0.125% bupivacaine compared to 0.25% bupivacaine for ultrasound-guided transversus abdominis plane (TAP) block in patients undergoing open inguinal hernia repair. Design Randomized, double-blind study. Setting Educational and research hospita...

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Bibliographic Details
Published in:	Journal of clinical anesthesia Vol. 28; pp. 41 - 46
Main Authors:	Erdoan Ari, Dilek, Yildirim Ar, Arzu, Karadoan, Firdevs, Oezcabi, Yetkin, Kocolu, Ayseguel, Kilic, Fatih, Akguen, Fatma Nur
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-02-2016 Elsevier Limited
Subjects:	Abdomen Abdominal Muscles - diagnostic imaging Abdominal surgery Adult Aged Analgesics Analgesics, Opioid - administration & dosage Analgesics, Opioid - therapeutic use Anesthesia Anesthesia & Perioperative Care Anesthesia, Spinal - methods Anesthetics, Local - administration & dosage Bupivacaine Bupivacaine - administration & dosage Double-Blind Method Drug dosages Elective Surgical Procedures Female Hernia, Inguinal - surgery Hernias Herniorrhaphy - methods Humans Male Medical personnel Middle Aged Morphine - administration & dosage Morphine - therapeutic use Nerve Block - methods Open inguinal hernia repair Pain management Pain Measurement Pain Medicine Pain, Postoperative - drug therapy Patient satisfaction Performance evaluation Plasma Postoperative analgesia Surgery Transversus abdominis plane block Ultrasonography, Interventional - methods Vomiting Open inguinal hernia repair Bupivacaine Transversus abdominis plane block Postoperative analgesia
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Summary:	Abstract Study objective To evaluate the effectiveness of 0.125% bupivacaine compared to 0.25% bupivacaine for ultrasound-guided transversus abdominis plane (TAP) block in patients undergoing open inguinal hernia repair. Design Randomized, double-blind study. Setting Educational and research hospital. Patients Forty adult patients of American Society of Anesthesiologists physical status I-III undergoing elective primary unilateral open inguinal hernia repair under spinal anesthesia. Interventions Patients in group I received 20 mL of 0.25% bupivacaine, whereas patients in group II received 20 mL of 0.125% bupivacaine for TAP block at the end of the surgery. Measurements Pain intensity was assessed at rest and during coughing using 10-cm visual analog scale score at 5, 15, 30, and 45 minutes and 1, 2, 4, 6, 12, and 24 hours after TAP block. Morphine consumption and time to first morphine requirement were recorded. Main results Visual analog scale scores at rest and during coughing were not significantly different between groups at all time points measured. Twenty-four hours of morphine consumption (7.72 ± 7.33 mg in group I and 6.06 ± 5.20 mg in group II; P = .437) and time to first morphine requirement (182.35 ± 125.16 minutes in group I and 143.21 ± 87.28 minutes in group II; P = .332) were not different between groups. Conclusions 0.125% Bupivacaine provides similar analgesic effect compared to 0.25% bupivacaine for ultrasound-guided TAP block in patients undergoing open inguinal hernia repair.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-News-1 ObjectType-Feature-3 content type line 23 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	0952-8180 1873-4529
DOI:	10.1016/j.jclinane.2015.07.020