Search Results - "Akerblad, Peter"

Regulation of early adipose commitment by Zfp521 by Kang, Sona, Akerblad, Peter, Kiviranta, Riku, Gupta, Rana K, Kajimura, Shingo, Griffin, Michael J, Min, Jie, Baron, Roland, Rosen, Evan D

“…While there has been significant progress in determining the transcriptional cascade involved in terminal adipocyte differentiation, less is known about early…”
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A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans by Cuchel, Marina, Raper, Anna C., Conlon, Donna M., Pryma, Daniel A., Freifelder, Richard H., Poria, Rahul, Cromley, Debra, Li, Xiaoyu, Dunbar, Richard L., French, Benjamin, Qu, Liming, Farver, William, Su, Ching-Chiang, Lund-Katz, Sissel, Baer, Amanda, Ruotolo, Giacomo, Akerblad, Peter, Ryan, Carol S., Xiao, Lan, Kirchgessner, Todd G., Millar, John S., Billheimer, Jeffrey T., Rader, Daniel J.

“…Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with…”
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Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice by Lindén, Daniel, Ahnmark, Andrea, Pingitore, Piero, Ciociola, Ester, Ahlstedt, Ingela, Andréasson, Anne-Christine, Sasidharan, Kavitha, Madeyski-Bengtson, Katja, Zurek, Magdalena, Mancina, Rosellina M., Lindblom, Anna, Bjursell, Mikael, Böttcher, Gerhard, Ståhlman, Marcus, Bohlooly-Y, Mohammad, Haynes, William G., Carlsson, Björn, Graham, Mark, Lee, Richard, Murray, Sue, Valenti, Luca, Bhanot, Sanjay, Åkerblad, Peter, Romeo, Stefano

“…Nonalcoholic fatty liver disease (NAFLD) is becoming a leading cause of advanced chronic liver disease. The progression of NAFLD, including nonalcoholic…”
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Critical Role for Ebf1 and Ebf2 in the Adipogenic Transcriptional Cascade by Jimenez, Maria A., Åkerblad, Peter, Sigvardsson, Mikael, Rosen, Evan D.

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Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis by Ghallab, Ahmed, González, Daniela, Strängberg, Ellen, Hofmann, Ute, Myllys, Maiju, Hassan, Reham, Hobloss, Zaynab, Brackhagen, Lisa, Begher-Tibbe, Brigitte, Duda, Julia C., Drenda, Carolin, Kappenberg, Franziska, Reinders, Joerg, Friebel, Adrian, Vucur, Mihael, Turajski, Monika, Seddek, Abdel-latief, Abbas, Tahany, Abdelmageed, Noha, Morad, Samy A.F., Morad, Walaa, Hamdy, Amira, Albrecht, Wiebke, Kittana, Naim, Assali, Mohyeddin, Vartak, Nachiket, van Thriel, Christoph, Sous, Ansam, Nell, Patrick, Villar-Fernandez, Maria, Cadenas, Cristina, Genc, Erhan, Marchan, Rosemarie, Luedde, Tom, Åkerblad, Peter, Mattsson, Jan, Marschall, Hanns-Ulrich, Hoehme, Stefan, Stirnimann, Guido, Schwab, Matthias, Boor, Peter, Amann, Kerstin, Schmitz, Jessica, Bräsen, Jan H., Rahnenführer, Jörg, Edlund, Karolina, Karpen, Saul J., Simbrunner, Benedikt, Reiberger, Thomas, Mandorfer, Mattias, Trauner, Michael, Dawson, Paul A., Lindström, Erik, Hengstler, Jan G.

“…Cholemic nephropathy (CN) is a severe complication of cholestatic liver diseases for which there is no specific treatment. We revisited its pathophysiology…”
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A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans by Caballero-Camino, Francisco J, Rodrigues, Pedro M, Wångsell, Fredrik, Agirre-Lizaso, Aloña, Olaizola, Paula, Izquierdo-Sanchez, Laura, Perugorria, Maria J, Bujanda, Luis, Angelin, Bo, Straniero, Sara, Wallebäck, Anna, Starke, Ingemar, Gillberg, Per-Göran, Strängberg, Ellen, Bonn, Britta, Mattsson, Jan P, Madsen, Martin R, Hansen, Henrik H, Lindström, Erik, Åkerblad, Peter, Banales, Jesus M

“…Cholestasis is characterized by intrahepatic accumulation of bile constituents, including bile acids (BAs), which promote liver damage. The apical…”
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Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands by Belorusova, Anna Y., Evertsson, Emma, Hovdal, Daniel, Sandmark, Jenny, Bratt, Emma, Maxvall, Ingela, Schulman, Ira G., Åkerblad, Peter, Lindstedt, Eva-Lotte

“…Liver X receptors (LXRs) are attractive drug targets for cardiovascular disease treatment due to their role in regulating cholesterol homeostasis and immunity…”
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Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development by Smith, Emma M.K., Åkerblad, Peter, Kadesch, Tom, Axelson, Håkan, Sigvardsson, Mikael

“…The Notch signaling pathway is involved in several lineage commitment and differentiation events. One of these is fate determination of the common lymphoid…”
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Early B-Cell Factor (O/E-1) Is a Promoter of Adipogenesis and Involved in Control of Genes Important for Terminal Adipocyte Differentiation by Aåkerblad, Peter, Lind, Ulrika, Liberg, David, Bamberg, Krister, Sigvardsson, Mikael

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Inhibition of the renal apical sodium-dependent bile acid transporter prevents cholemic nephropathy by Ghallab, Ahmed, González, Daniela, Strängberg, Ellen, Hofmann, Ute, Myllys, Maiju, Hassan, Reham, Lüdde, Tom, Akerblad, Peter, Mattsson, Jan, Marschall, Hanns-Ulrich, Dawson, Paul, Stirnimann, Guido, Boor, Peter, Edlund, Karolina, Trauner, Michael, Lindström, Erik, Hengstler, Jan G.

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THU-249 - Inhibition of the renal apical sodium-dependent bile acid transporter prevents cholemic nephropathy by Ghallab, Ahmed, González, Daniela, Strängberg, Ellen, Hofmann, Ute, Myllys, Maiju, Hassan, Reham, Lüdde, Tom, Akerblad, Peter, Mattsson, Jan, Marschall, Hanns-Ulrich, Dawson, Paul, Stirnimann, Guido, Boor, Peter, Edlund, Karolina, Trauner, Michael, Lindström, Erik, Hengstler, Jan G.

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Activation of Peroxisome Proliferator-activated Receptor α Increases the Expression and Activity of Microsomal Triglyceride Transfer Protein in the Liver by Améen, Caroline, Edvardsson, Ulrika, Ljungberg, Anna, Asp, Lennart, Åkerblad, Peter, Tuneld, Anna, Olofsson, Sven-Olof, Lindén, Daniel, Oscarsson, Jan

“…Microsomal triglyceride transfer protein (MTP) is rate-limiting in the assembly and secretion of lipoproteins containing apolipoprotein (apo) B. Previously we…”
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Dual ileal/renal-liver bile acid transporter inhibitors with different transporter selectivity in vitro differentially increase faecal and urinary bile acid excretion in organic anion transporting polypeptide 1a/1b knockout mice in vivo by Strängberg, Ellen, Gillberg, Per-Goran, Uzelac, Ivana, Starke, Ingemar, Bonn, Britta, Mattsson, Jan, Akerblad, Peter, Pal, Runa, Gaur, Ashwani, Kangarajan, Ramesh, Singh, Shivendra, Kulkarni, Santosh, Dawson, Paul, Lindström, Erik

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Su1327: DUAL ACTING ILEAL/RENAL-LIVER BILE ACID TRANSPORTER INHIBITORS SIGNIFICANTLY INCREASE URINARY EXCRETION OF NON-SULFATED BILE ACIDS IN A DIETHOXY-CARBONYL-DIHYDRO-COLLIDINE-INDUCED MOUSE MODEL OF CHOLESTASIS by Rao, Anuradha, Pachura, Kim, Strangberg, Ellen, Gillberg, Per-Göran, Uzelac, Ivana, Starke, Ingemar, Bonn, Britta, Mattsson, Jan P., Akerblad, Peter, Straniero, Sara, Rudling, Mats, Angelin, Bo, Lindstrom, Erik, Karpen, Saul J., Dawson, Paul A.

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OS-074-YI - A3907, a systemic ASBT inhibitor, improves cholestasis in mice by inhibiting multi-organ bile acid transport and shows translational relevance to human by Caballero, Francisco J., Rodrigues, Pedro Miguel, Lizaso, Aloña Agirre, Olaizola, Paula, Izquierdo-Sánchez, Laura, Perugorria, María Jesús, Bujanda, Luis, Angelin, Bo, Straniero, Sara, Wallebäck, Anna, Starke, Ingemar, Gillberg, Per-Göran, Strängberg, Ellen, Wangsell, Fredrik, Mattsson, Jan, Hansen, Henrik B., Lindström, Erik, Akerblad, Peter, Banales, Jesus Maria

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The EBF/Olf/Collier Family of Transcription Factors: Regulators of Differentiation in Cells Originating from All Three Embryonal Germ Layers by Liberg, David, Sigvardsson, Mikael, Aåkerblad, Peter

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Early B-Cell Factor, E2A, and Pax-5 Cooperate To Activate the Early B Cell-Specific mb-1 Promoter by Sigvardsson, Mikael, Clark, Dawn R., Fitzsimmons, Daniel, Doyle, Michelle, Aåkerblad, Peter, Breslin, Thomas, Bilke, Sven, Li, Ronggui, Yeamans, Carmen, Zhang, Gongyi, Hagman, James

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IDOL regulates systemic energy balance through control of neuronal VLDLR expression by Lee, Stephen D., Priest, Christina, Bjursell, Mikael, Gao, Jie, Arneson, Douglas V., Ahn, In Sook, Diamante, Graciel, van Veen, J. Edward, Massa, Megan G., Calkin, Anna C., Kim, Jason, Andersén, Harriet, Rajbhandari, Prashant, Porritt, Michelle, Carreras, Alba, Ahnmark, Andrea, Seeliger, Frank, Maxvall, Ingela, Eliasson, Pernilla, Althage, Magnus, Åkerblad, Peter, Lindén, Daniel, Cole, Tracy A., Lee, Richard, Boyd, Helen, Bohlooly-Y, Mohammad, Correa, Stephanie M., Yang, Xia, Tontonoz, Peter, Hong, Cynthia

“…Liver X receptors limit cellular lipid uptake by stimulating the transcription of inducible degrader of the low-density lipoprotein receptor (IDOL), an E3…”
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A3907, a systemic ASBT inhibitor, improves cholestasis in mice by inhibiting multi-organ bile acid transport and shows translational relevance to human by Caballero, Francisco J., Rodrigues, Pedro Miguel, Lizaso, Aloña Agirre, Olaizola, Paula, Izquierdo-Sánchez, Laura, Perugorria, María Jesús, Bujanda, Luis, Angelin, Bo, Straniero, Sara, Wallebäck, Anna, Starke, Ingemar, Gillberg, Per-Göran, Strängberg, Ellen, Wangsell, Fredrik, Mattsson, Jan, Hansen, Henrik B., Lindström, Erik, Akerblad, Peter, Banales, Jesus Maria

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High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets by Woo, Laura A., Tkachenko, Svyatoslav, Ding, Mei, Plowright, Alleyn T., Engkvist, Ola, Andersson, Henrik, Drowley, Lauren, Barrett, Ian, Firth, Mike, Akerblad, Peter, Wolf, Matthew J., Bekiranov, Stefan, Brautigan, David L., Wang, Qing-Dong, Saucerman, Jeffrey J.

“…Over 5 million people in the United States suffer from heart failure, due to the limited ability to regenerate functional cardiac tissue. One potential…”
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