Search Results - "Aker, Rezzan Gulhan"

Review of detection frequency and type of synthetic cannabinoids in herbal compounds analyzed by Istanbul Narcotic Department of the Council of Forensic Medicine, Turkey by Gurdal, Fatma, Asirdizer, Mahmut, M.D, Aker, Rezzan Gulhan, M.D, Korkut, Senol, Gocer, Yasemin, Kucukibrahimoglu, E. Esra, M.D, Ince, C. Haluk, M.D

“…Abstract In recent years, synthetic cannabinoids have been frequently observed in seized materials all over the world. This new generation of designer drugs,…”
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IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence by Akin, Demet, Ravizza, Teresa, Maroso, Mattia, Carcak, Nihan, Eryigit, Tugba, Vanzulli, Ilaria, Aker, Rezzan Gülhan, Vezzani, Annamaria, Onat, Filiz Yılmaz

“…Abstract Interleukin (IL)-1β plays a crucial role in the mechanisms of limbic seizures in rodent models of temporal lobe epilepsy. We addressed whether…”
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Cardiovascular regulation through hypothalamic GABA(A) receptors in a genetic absence epilepsy model in rat by Aker, Rezzan Gülhan, Onat, Filiz Yilmaz

“…Gamma-aminobutyric acid (GABA) plays a vital role in both central cardiovascular homeostasis and pathogenesis of epilepsy. Epilepsy affects autonomic nervous…”
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A review of suspected cases of driving under the influence of drugs (DUID) involved in traffic accidents in Istanbul (Turkey) by Acar, Fatih, Asirdizer, Mahmut, M.D, Aker, Rezzan Gulhan, M.D, Kucukibrahimoglu, E. Esra, M.D, Ates, Ismail, Erol, Yeter, Sahin, Aysegul

“…Abstract Nowadays traffic accidents, which have high mortality and morbidity, are an important public health problem. The association between the use of…”
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The relationship between age-related development of spike-and-wave discharges and the resistance to amygdaloid kindling in rats with genetic absence epilepsy by Çarçak, Nihan, Aker, Rezzan Gülhan, Özdemir, Osman, Demiralp, Tamer, Onat, Filiz Yılmaz

“…Abstract Genetic Absence Epilepsy Rats from Strasbourg (GAERS) are resistant to amygdaloid kindling. Since in GAERS the characteristics of spike-and-wave…”
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Hippocampal neuronal damage in rats exposed to a double hit: irradiation and hyperthermia by Senturk, Gozde Erkanli, Isler, Cihan, Kemerdere, Rahsan, Ulu, Mustafa Onur, Umay, Cenk, Ozkaymakci, Aydan, Aker, Gulhan Rezzan, Ercan, Feriha, Ozkara, Cigdem, Onat, Filiz, Uzan, Mustafa

“…In utero irradiation models induce diffuse neuronal damage. Experimental studies have shown that hyperthermia induced seizures are easily elicited and have…”
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Intra-Amygdaloid Injection of Kainic Acid in Rats with Genetic Absence Epilepsy: The Relationship of Typical Absence Epilepsy and Temporal Lobe Epilepsy by Gurbanova, Ayten Azizova, Aker, Rezzan Gulhan, Sirvanci, Serap, Demiralp, Tamer, Onat, Filiz Yilmaz

“…We showed previously that genetic absence epilepsy rats from Strasbourg (GAERS) resist secondary generalization of focal limbic seizures after electrical…”
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Cardiovascular Regulation through Hypothalamic GABAA Receptors in a Genetic Absence Epilepsy Model in Rat by Aker, Rezzan Gülhan, Onat, Filiz Yılmaz

“…Purpose: γ‐Aminobutyric acid (GABA) plays a vital role in both central cardiovascular homeostasis and pathogenesis of epilepsy. Epilepsy affects autonomic…”
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The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy by Gulcebi, Medine Idrizoglu, Ozkaynakcı, Aydan, Goren, Mehmet Zafer, Aker, Rezzan Gulhan, Ozkara, Cigdem, Onat, Filiz Yılmaz

“…Summary Lamotrigine (LTG) which has a widespread use in epilepsy treatment as an antiepileptic agent is metabolized by UDP-glucuronosyl transferase (UGT)…”
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Changes in intracellular protein expression in cortex, thalamus and hippocampus in a genetic rat model of absence epilepsy by Danış, Özkan, Demir, Serap, Günel, Aslıhan, Aker, Rezzan Gülhan, Gülçebi, Medine, Onat, Filiz, Ogan, Ayşe

“…Abstract Epilepsy is a chronic disorder characterized by repeated seizures resulting from abnormal activation of neurons in the brain. Although mutations in…”
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The Effect of Generalized Absence Seizures on the Progression of Kindling in the Rat by Onat, Filiz Yılmaz, Aker, Rezzan Gülhan, Gurbanova, Ayten Azizova, Ateş, Nurbay, Van Luijtelaar, Gilles

“…The involvement of the thalamus in limbic epileptogenesis has recently drawn attention to the connectivity between the nuclei of the thalamus and limbic…”
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Localized cortical injections of ethosuximide suppress spike-and-wave activity and reduce the resistance to kindling in genetic absence epilepsy rats (GAERS) by Gülhan Aker, Rezzan, Tezcan, Kutluhan, Çarçak, Nihan, Sakallı, Eren, Akın, Demet, Onat, Filiz Yılmaz

“…Summary Models of genetic absence epilepsy are resistant to secondary generalization of focal limbic seizures. This correlates with the postnatal development…”
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Effect of stage 2 kindling on local cerebral blood flow rates in rats with genetic absence epilepsy by Çarçak, Nihan, Ferrandon, Arielle, Koning, Estelle, Aker, Rezzan Gülhan, Özdemir, Osman, Onat, Filiz Yilmaz, Nehlig, Astrid

“…Summary Purpose:  Genetic absence epilepsy rats from Strasbourg (GAERS) are resistant to the progression of kindling seizures. We studied local cerebral blood…”
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Anticonvulsant activity of 3,5-dimethylpyrazole derivatives in animal models by Kocyigit-Kaymakcioglu, Bedia, Aker, Rezzan Gülhan, Tezcan, Kutluhan, Sakalli, Eren, Ketenci, Sema, Oruç-Emre, Emine Elçin, Akin, Demet, Gurbanova, Ayten, Terzioglu, Berna, Onat, Filiz, Rollas, Sevim

“…A series of 3,5-dimethylpyrazole derivatives, structurally related to the previously described potent ameltolide analogues, were synthesized and evaluated for…”
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GABA A receptor mediated transmission in the thalamic reticular nucleus of rats with genetic absence epilepsy shows regional differences: Functional implications by Aker, Rezzan Gülhan, Özyurt, Hazan B., Yananli, Hasan R., Özgür Çakmak, Yusuf, Özkaynakçi, Aydan E., Sehirli, Ümit, Saka, Erdinç, Çavdar, Safiye, Onat, Filiz Yılmaz

“…The aim of the present study was to investigate the effect of local injections of the GABA A receptor antagonist, bicuculline, into the rostral and caudal…”
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Perirhinal cortical kindling in rats with genetic absence epilepsy by Akman, Ozlem, Karson, Ayse, Aker, Rezzan Gulhan, Ates, Nurbay, Onat, Filiz Yilmaz

“…Two genetic models of absence epilepsy, GAERS and WAG/Rij rat strains, are resistant to progression of partial seizures induced by amygdaloid or hippocampal…”
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Hippocampal kindling in rats with absence epilepsy resembles amygdaloid kindling by Akman, Ozlem, Karson, Ayse, Aker, Rezzan Gulhan, Ates, Nurbay, Onat, Filiz Yilmaz

“…Summary Purpose WAG/Rij and GAERS rats show delays or resistance to secondary generalization of limbic seizures during amygdaloid kindling. In this study, we…”
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Amygdala Kindling in the WAG/Rij Rat Model of Absence Epilepsy by Aker, Rezzan Gülhan, Yananli, Hasan Raci, Gurbanova, Ayten Azizova, Özkaynakçi, Aydan Ergün, Ateş, Nurbay, Luijtelaar, Gilles, Onat, Filiz Yilmaz

“…Purpose: The kindling model in rats with genetic absence epilepsy is suitable for studying mechanisms involved in the propagation and generalization of seizure…”
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GABAA receptor mediated transmission in the thalamic reticular nucleus of rats with genetic absence epilepsy shows regional differences : Functional implications by AKER, Rezzan Gülhan, ÖZYURT, Hazan B, YANANLI, Hasan R, CAKMAK, Yusuf Özgür, ÖZKAYNAKCI, Aydan E, SEHIRLI, Ümit, SAKA, Erdinc, CAVDAR, Safiye, ONAT, Filiz Yilmaz

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Enhancement of spike and wave discharges by microinjection of bicuculline into the reticular nucleus of rats with absence epilepsy by Aker, Rezzan Gülhan, Özkara, Çiğdem, Dervent, Ayşın, Yılmaz Onat, Filiz

“…The aim of this study was to demonstrate the effect of administration of gamma-aminobutyric acid (GABA) A receptor antagonist, bicuculline, into the reticular…”
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