Search Results - "Akens, Margarete"

Impact of radiofrequency ablation (RFA) on bone quality in a murine model of bone metastases by Ghomashchi, Soroush, Whyne, Cari M, Chinnery, Tricia, Habach, Fayez, Akens, Margarete K

“…Thermal therapies such as radiofrequency ablation (RFA) are gaining widespread clinical adoption in the local treatment of skeletal metastases. RFA has been…”
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Hierarchical Model of Fibrillar Collagen Organization for Interpreting the Second-Order Susceptibility Tensors in Biological Tissue by Tuer, Adam E., Akens, Margarete K., Krouglov, Serguei, Sandkuijl, Daaf, Wilson, Brian C., Whyne, Cari M., Barzda, Virginijus

“…The second-order nonlinear polarization properties of fibrillar collagen in various rat tissues (vertebrae, tibia, tail tendon, dermis, and cornea) are…”
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Establishment and Image based evaluation of a New Preclinical Rat Model of Osteoblastic Bone Metastases by Ghomashchi, Soroush, Clement, Allison, Whyne, Cari M., Akens, Margarete K.

“…Bone remodeling is disrupted in the presence of metastases and can present as osteolytic, osteoblastic or a mixture of the two. Established rat models of…”
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Polarimetric second harmonic generation microscopy of partially oriented fibers II: Imaging study by Alizadeh, Mehdi, Habach, Fayez, Maciulis, Mykolas, Kontenis, Lukas, Bagdonas, Saulius, Krouglov, Serguei, Baranauskas, Vytautas, Bulotiene, Danute, Karabanovas, Vitalijus, Rotomskis, Ricardas, Akens, Margarete K., Barzda, Virginijus

“…Polarimetric second harmonic generation (SHG) microscopy imaging is employed to investigate the ultrastructural organization of biological and biomimetic…”
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Complex Susceptibilities and Chiroptical Effects of Collagen Measured with Polarimetric Second-Harmonic Generation Microscopy by Golaraei, Ahmad, Kontenis, Lukas, Mirsanaye, Kamdin, Krouglov, Serguei, Akens, Margarete K., Wilson, Brian C., Barzda, Virginijus

“…Nonlinear optical properties of collagen type-I are investigated in thin tissue sections of pig tendon as a research model using a complete polarimetric…”
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Collagen chirality and three‐dimensional orientation studied with polarimetric second‐harmonic generation microscopy by Golaraei, Ahmad, Mirsanaye, Kamdin, Ro, Yeji, Krouglov, Serguei, Akens, Margarete K., Wilson, Brian C., Barzda, Virginijus

“…Polarization‐dependent second‐harmonic generation (P‐SHG) microscopy is used to characterize molecular nonlinear optical properties of collagen and determine a…”
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Irregular porous titanium enhances implant stability and bone ingrowth in an intra‐articular ovine model by Changoor, Adele, Suderman, R. Peter, Alshaygy, Ibrahim, Fuhrmann, Ariel, Akens, Margarete K., Safir, Oleg, Grynpas, Marc D., Kuzyk, Paul R. T.

“…Two commercially available porous coatings, Gription and Porocoat, were compared for the first time in a challenging intra‐articular, weight‐bearing, ovine…”
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Elevated Microdamage Spatially Correlates with Stress in Metastatic Vertebrae by Atkins, Ayelet, Burke, Mikhail, Samiezadeh, Saeid, Akens, Margarete K., Hardisty, Michael, Whyne, Cari M.

“…Metastasis of cancer to the spine impacts bone quality. This study aims to characterize vertebral microdamage secondary to metastatic disease considering the…”
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Photodynamic therapy outcome modelling for patients with spinal metastases: a simulation-based study by Yassine, Abdul-Amir, Lo, William C. Y., Saeidi, Tina, Ferguson, Dallis, Whyne, Cari M., Akens, Margarete K., Betz, Vaughn, Lilge, Lothar

“…Spinal metastases often occur in the advanced stages of breast, lung or prostate cancer, resulting in a significant impact on the patient’s quality of life…”
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A multimodal nano agent for image-guided cancer surgery by Zheng, Jinzi, Muhanna, Nidal, De Souza, Raquel, Wada, Hironobu, Chan, Harley, Akens, Margarete K, Anayama, Takashi, Yasufuku, Kazuhiro, Serra, Stefano, Irish, Jonathan, Allen, Christine, Jaffray, David

“…Abstract Intraoperative imaging technologies including computed tomography and fluorescence optical imaging are becoming routine tools in the cancer surgery…”
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Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models by Muhanna, Nidal, Jin, Cheng S, Huynh, Elizabeth, Chan, Harley, Qiu, Yi, Jiang, Wenlei, Cui, Liyang, Burgess, Laura, Akens, Margarete K, Chen, Juan, Irish, Jonathan C, Zheng, Gang

“…Head and neck cancer is the fifth most common type of cancer worldwide and remains challenging for effective treatment due to the proximity to critical…”
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μFE models can represent microdamaged regions of healthy and metastatically involved whole vertebrae identified through histology and contrast enhanced μCT imaging by Choudhari, Chetan, Chan, Katelyn, Akens, Margarete K, Whyne, Cari M

“…Abstract Microdamage formation within the skeleton is an important stimulant for bone remodelling, however abnormal build-up of microdamage can lead to…”
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Closure of the annulus fibrosus of the intervertebral disc using a novel suture application device – in vivo porcine and ex-vivo biomechanical evaluation by Bateman, Antony H, MSc FRCS (Orth), Balkovec, Christian, BSc, Akens, Margarete K, PhD, Chan, Andrea H W, HBSc MA MD, Harrison, Robert D, M.A.Sc, Oakden, Wendy, PhD, Yee, Albert J M, MD MSc, McGill, Stuart M, PhD

“…Structured Abstract Background Context Defects in the annulus fibrosus (AF) remain a challenge in the surgical treatment of lumbar disc herniations with…”
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Wide‐field Stokes polarimetric microscopy for second harmonic generation imaging by Uribe Castaño, Leonardo, Mirsanaye, Kamdin, Kontenis, Lukas, Krouglov, Serguei, Žurauskas, Edvardas, Navab, Roya, Yasufuku, Kazuhiro, Tsao, Ming‐Sound, Akens, Margarete K., Wilson, Brian C., Barzda, Virginijus

“…We employ wide‐field second harmonic generation (SHG) microscopy together with nonlinear Stokes polarimetry for quick ultrastructural investigation of large…”
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Nanoparticle-based sorting of circulating tumor cells by epithelial antigen expression during disease progression in an animal model by Muhanna, Nidal, MD, PhD, Mepham, Adam, Mohamadi, Reza M., PhD, Chan, Harley, PhD, Khan, Tahsin, Akens, Margarete, PhD, Besant, Justin D, Irish, Jonathan, MD, MSc, Kelley, Shana O., PhD

“…Abstract Circulating tumor cells (CTCs) can be used as markers for the detection, characterization, and targeted therapeutic management of cancer. We recently…”
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The impact of thermal cycling on Staphylococcus aureus biofilm growth on stainless steel and titanium orthopaedic plates by Akens, Margarete K, Chien, Claudia, Katchky, Ryan N, Kreder, Hans J, Finkelstein, Joel, Whyne, Cari M

“…Orthopaedic implant infections are difficult to eradicate because bacteria adhering to implant surfaces inhibit the ability of the immune system and…”
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Development and validation of a radiofrequency ablation treatment planning system for vertebral metastases by Whyne, Cari M., Underwood, Grace, Davidson, Sean R. H., Robert, Normand, Huang, Christine, Akens, Margarete K., Fichtinger, Gabor, Yee, Albert J. M., Hardisty, Michael

“…Purpose Bone-targeted radiofrequency ablation (RFA) is widely used in the treatment of vertebral metastases. While radiation therapy utilizes established…”
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Quantitative MRI assessment of VX2 tumour oxygenation changes in response to hyperoxia and hypercapnia by Winter, Jeff D, Akens, Margarete K, Cheng, Hai-Ling Margaret

“…Magnetic resonance imaging (MRI) relaxation times provide indirect estimates of tissue O(2) for monitoring tumour oxygenation. This study provides insight into…”
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In vivo effects of low level laser therapy on inducible nitric oxide synthase by Moriyama, Yumi, Nguyen, Jacqueline, Akens, Margarete, Moriyama, Eduardo H., Lilge, Lothar

“…Background and Objective Low level laser therapy (LLLT) has been demonstrated to modulate inflammatory processes with evidence suggesting that treatment…”
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Imaging of Specific Activation of Photodynamic Molecular Beacons in Breast Cancer Vertebral Metastases by Liu, Tracy W, Akens, Margarete K, Chen, Juan, Wise-Milestone, Lisa, Wilson, Brian C, Zheng, Gang

“…Breast cancer is the second leading cause of cancer-related death in women. Approximately 85% of patients with advanced cases will develop spinal metastases…”
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