Search Results - "Akehi, Masaru"

Novel single‐chain variant of antibody against mesothelin established by phage library by Yakushiji, Hiromasa, Kobayashi, Kazuko, Takenaka, Fumiaki, Kishi, Yoshiro, Shinohara, Midori, Akehi, Masaru, Sasaki, Takanori, Ohno, Eiji, Matsuura, Eiji

“…Mesothelin (MSLN) shows increased expression in various cancer cells. For clinical application of antibodies as a positron emission tomography (PET) imaging…”
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Fluorine-18 (18F)-labeled retinoid x receptor (RXR) partial agonist whose tissue transferability is affected by other RXR ligands by Takamura, Yuta, Shibahara, Osamu, Watanabe, Masaki, Fujihara, Michiko, Yamada, Shoya, Akehi, Masaru, Sasaki, Takanori, Hirano, Hiroyuki, Kakuta, Hiroki

“…[Display omitted] Bexarotene (1), a retinoid X receptor (RXR) agonist approved for the treatment of cutaneous T cell lymphoma (CTCL), was reported to migrate…”
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Novel Self-Forming Nanosized DDS Particles for BNCT: Utilizing A Hydrophobic Boron Cluster and Its Molecular Glue Effect by Fithroni, Abdul Basith, Kobayashi, Kazuko, Uji, Hirotaka, Ishimoto, Manabu, Akehi, Masaru, Ohtsuki, Takashi, Matsuura, Eiji

“…BNCT is a non-invasive cancer therapy that allows for cancer cell death without harming adjacent cells. However, the application is limited, owing to the…”
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In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging by Saito, Yukihiro, Nose, Naoko, Iida, Toshihiro, Akazawa, Kaoru, Kanno, Takayuki, Fujimoto, Yuki, Sasaki, Takanori, Akehi, Masaru, Higuchi, Takahiro, Akagi, Satoshi, Yoshida, Masashi, Miyoshi, Toru, Ito, Hiroshi, Nakamura, Kazufumi

“…Introduction Transplantation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is a promising treatment for heart failure. Information…”
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Synthesis of 11C‑Labeled RXR Partial Agonist 1‑[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [11C]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof by Shibahara, Osamu, Watanabe, Masaki, Yamada, Shoya, Akehi, Masaru, Sasaki, Takanori, Akahoshi, Akiya, Hanada, Takahisa, Hirano, Hiroyuki, Nakatani, Shunsuke, Nishioka, Hiromi, Takeuchi, Yasuo, Kakuta, Hiroki

“…The retinoid X receptor (RXR) partial agonist 1-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)­amino]­benzotriazole-5-carboxylic acid (1; CBt-PMN,…”
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A Novel 89Zr-labeled DDS Device Utilizing Human IgG Variant (scFv): “Lactosome” Nanoparticle-Based Theranostics for PET Imaging and Targeted Therapy by Lim, Melissa Siaw Han, Ohtsuki, Takashi, Takenaka, Fumiaki, Kobayashi, Kazuko, Akehi, Masaru, Uji, Hirotaka, Kobuchi, Hirotsugu, Sasaki, Takanori, Ozeki, Eiichi, Matsuura, Eiji

“…“Theranostics,” a new concept of medical advances featuring a fusion of therapeutic and diagnostic systems, provides promising prospects in personalized…”
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Kinetic Resolution of Secondary Alcohols by Chiral DMAP Derivatives Prepared by the Ugi Multicomponent Reaction by Mandai, Hiroki, Suga, Seiji, Irie, Shunsuke, Akehi, Masaru, Yuri, Kazunobu, Yoden, Masaaki, Mitsudo, Koichi

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Positron Emission Tomography to Elucidate Pharmacokinetic Differences of Regioisomeric Retinoid X Receptor Agonists by Kobayashi, Toshiki, Furusawa, Yuki, Yamada, Shoya, Akehi, Masaru, Takenaka, Fumiaki, Sasaki, Takanori, Akahoshi, Akiya, Hanada, Takahisa, Matsuura, Eiji, Hirano, Hiroyuki, Tai, Akihiro, Kakuta, Hiroki

“…RXR partial agonist NEt-4IB (2a, 6-[ethyl-(4-isobutoxy-3-isopropylphenyl)amino]pyridine-3-carboxylic acid: EC50 = 169 nM, E max = 55%) showed a blood…”
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Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/ lpr Lupus-Prone Mice by Watanabe, Haruki, Watanabe, Katsue S, Liu, Keyue, Hiramatsu, Sumie, Zeggar, Sonia, Katsuyama, Eri, Tatebe, Noriko, Akahoshi, Akiya, Takenaka, Fumiaki, Hanada, Takahisa, Akehi, Masaru, Sasaki, Takanori, Sada, Ken-Ei, Matsuura, Eiji, Nishibori, Masahiro, Wada, Jun

“…We evaluated the efficacy of a neutralizing anti-high mobility group box 1 (HMGB1) monoclonal antibody in MRL/ lupus-prone mice. The anti-HMGB1 monoclonal…”
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The Function of β2-glycoprotein I in Angiogenesis and Its in Vivo Distribution in Tumor Xenografts by Wahyuningsih, Arum Tri, Shen, Lianhua, Kobayashi, Kazuko, Sasaki, Takanori, Takenaka, Fumiaki, Hanada, Takahisa, Akehi, Masaru, Akahoshi, Akiya, Ozeki, Eiichi, Ando, Eiji, Matsuura, Eiji

“…Intact β2-glycoprotein I (iβ2GPI) is a glycoprotein that regulates coagulation and fibrinolysis. Nicked β2GPI (nβ2GPI) possesses an angiogenic property at a…”
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Chiral 1-(1,3-dithian-2-yl) prop-2-en-1-ols: new scaffolds for enantiopure α-hydroxyaldehydes by Akehi, Masaru, Kawamoto, Mariko, Mandai, Tadakatsu

“…We have demonstrated that chiral 1-(1,3-dithian-2-yl)prop-2-en-1-ols as new scaffolds, obtained by enzyme-catalyzed kinetic resolution, undergo Suzuki-Miyaura…”
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Correction to Synthesis of 11 C-Labeled RXR Partial Agonist 1-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [ 11 C]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof by Shibahara, Osamu, Watanabe, Masaki, Takamura, Yuta, Yamada, Shoya, Akehi, Masaru, Sasaki, Takanori, Akahoshi, Akiya, Hanada, Takahisa, Hirano, Hiroyuki, Nakatani, Shunsuke, Nishioka, Hiromi, Takeuchi, Yasuo, Kakuta, Hiroki

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Correction to Synthesis of 11C‑Labeled RXR Partial Agonist 1‑[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro­naphthalen-2-yl)amino]­benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [11C]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof by Shibahara, Osamu, Watanabe, Masaki, Takamura, Yuta, Yamada, Shoya, Akehi, Masaru, Sasaki, Takanori, Akahoshi, Akiya, Hanada, Takahisa, Hirano, Hiroyuki, Nakatani, Shunsuke, Nishioka, Hiromi, Takeuchi, Yasuo, Kakuta, Hiroki

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Teratogenicity and Fetal-Transfer Assessment of the Retinoid X Receptor Agonist Bexarotene by Takamura, Yuta, Kato, Izumi, Fujita-Takahashi, Manami, Azuma-Nishii, Midori, Watanabe, Masaki, Nozaki, Rui, Akehi, Masaru, Sasaki, Takanori, Hirano, Hiroyuki, Kakuta, Hiroki

“…Bexarotene, a retinoid X receptor (RXR) agonist, is used to treat cutaneous T-cell lymphoma, and drug repositioning research has also been reported, despite…”
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Synthesis of 11 C-Labeled RXR Partial Agonist 1-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [ 11 C]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof by Shibahara, Osamu, Watanabe, Masaki, Yamada, Shoya, Akehi, Masaru, Sasaki, Takanori, Akahoshi, Akiya, Hanada, Takahisa, Hirano, Hiroyuki, Nakatani, Shunsuke, Nishioka, Hiromi, Takeuchi, Yasuo, Kakuta, Hiroki

“…The retinoid X receptor (RXR) partial agonist 1-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic acid (1; CBt-PMN, E…”
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A Novel 89 Zr-labeled DDS Device Utilizing Human IgG Variant (scFv): "Lactosome" Nanoparticle-Based Theranostics for PET Imaging and Targeted Therapy by Lim, Melissa Siaw Han, Ohtsuki, Takashi, Takenaka, Fumiaki, Kobayashi, Kazuko, Akehi, Masaru, Uji, Hirotaka, Kobuchi, Hirotsugu, Sasaki, Takanori, Ozeki, Eiichi, Matsuura, Eiji

“…"Theranostics," a new concept of medical advances featuring a fusion of therapeutic and diagnostic systems, provides promising prospects in personalized…”
Get full text