Search Results - "Akdis, Cezmi A."
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Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?
Published in Nature reviews. Immunology (01-11-2021)“…There has been a steep increase in allergic and autoimmune diseases, reaching epidemic proportions and now affecting more than one billion people worldwide…”
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Mechanisms of allergen-specific immunotherapy: Multiple suppressor factors at work in immune tolerance to allergens
Published in Journal of allergy and clinical immunology (01-03-2014)“…Allergen-specific immunotherapy (AIT) has been used for more than 100 years as a desensitizing therapy for IgE-mediated allergic diseases and represents a…”
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Allergic reactions to the first COVID‐19 vaccine: A potential role of polyethylene glycol?
Published in Allergy (Copenhagen) (01-06-2021)“…Although the trigger of the adverse allergic reactions suffered by the two NHS workers after receiving the vaccine BNT162b2 against COVID-19 has yet to be…”
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Global warming, climate change, air pollution and allergies
Published in Allergy (Copenhagen) (01-09-2020)Get full text
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Mechanisms of allergen-specific immunotherapy
Published in Journal of allergy and clinical immunology (01-01-2011)“…Allergen-specific immunotherapy has been used for 100 years as a desensitizing therapy for allergic diseases and represents the potentially curative and…”
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Environmental factors in epithelial barrier dysfunction
Published in Journal of allergy and clinical immunology (01-06-2020)“…The main interfaces controlling and attempting to homeostatically balance communications between the host and the environment are the epithelial barriers of…”
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Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19
Published in Allergy (Copenhagen) (01-07-2020)“…As a zoonotic disease that has already spread globally to several million human beings and possibly to domestic and wild animals, eradication of coronavirus…”
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World Health Organization global air quality guideline recommendations: Executive summary
Published in Allergy (Copenhagen) (01-07-2022)“…Air pollution is a leading cause of death globally and has resulted in the loss of millions of healthy years of life. Moreover, the health burden has fallen…”
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Type 2 immunity in the skin and lungs
Published in Allergy (Copenhagen) (01-07-2020)“…There has been extensive progress in understanding the cellular and molecular mechanisms of inflammation and immune regulation in allergic diseases of the skin…”
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Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs
Published in The Journal of clinical investigation (01-11-2014)“…During the past 20 years, major advances have been made in understanding the molecular and cellular mechanisms of allergen tolerance in humans. The…”
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Allergenic components of the mRNA‐1273 vaccine for COVID‐19: Possible involvement of polyethylene glycol and IgG‐mediated complement activation
Published in Allergy (Copenhagen) (01-11-2021)“…Following the emergency use authorization of the mRNA‐1273 vaccine on the 18th of December 2020, two mRNA vaccines are in current use for the prevention of…”
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Mechanisms of allergen-specific immunotherapy and immune tolerance to allergens
Published in The World Allergy Organization journal (2015)“…Substantial progress in understanding mechanisms of immune regulation in allergy, asthma, autoimmune diseases, tumors, organ transplantation and chronic…”
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Recent developments and advances in atopic dermatitis and food allergy
Published in Allergology international (01-04-2020)“…This review highlights recent advances in atopic dermatitis (AD) and food allergy (FA), particularly on molecular mechanisms and disease endotypes, recent…”
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Mechanisms of allergen-specific immunotherapy and allergen tolerance
Published in Allergology International (01-10-2020)“…Allergen-specific immunotherapy (AIT) is the mainstay treatment for the cure of allergic disorders, with depicted efficacy and safety by several trials and…”
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Advances in allergen immunotherapy: aiming for complete tolerance to allergens
Published in Science translational medicine (25-03-2015)“…Allergen-specific immunotherapy (AIT) has been used for more than 100 years as a tolerance-inducing therapy for allergic diseases and represents a potentially…”
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Endotypes of allergic diseases and asthma: An important step in building blocks for the future of precision medicine
Published in Allergology International (01-07-2016)“…Discoveries from basic science research in the last decade have brought significant progress in knowledge of pathophysiologic processes of allergic diseases,…”
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MicroRNAs: Essential players in the regulation of inflammation
Published in Journal of allergy and clinical immunology (01-07-2013)“…Regulation of inflammatory responses is ensured by coordinated control of gene expression in participating immune system and tissue cells. One group of gene…”
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Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease
Published in Allergy (Copenhagen) (01-05-2022)“…Environmental exposure plays a major role in the development of allergic diseases. The exposome can be classified into internal (e.g., aging, hormones, and…”
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Risk factors for severe and critically ill COVID‐19 patients: A review
Published in Allergy (Copenhagen) (01-02-2021)“…The pandemic of coronavirus disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented…”
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