Guided intraoperative scintigraphic tumor targeting of metastatic cervical lymph nodes in patients with differentiated thyroid cancer: a single-center report

Our aim was to present our experiences related to performing neck surgery using the guided intraoperative scintigraphic tumor targeting (GOSTT) procedure for patients who had locally recurrent or persistent differentiated thyroid cancer (DTC) and who had undergone previous thyroid surgery. We retros...

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Bibliographic Details
Published in:	Archives of Endocrinology and Metabolism Vol. 62; no. 5; pp. 495 - 500
Main Authors:	Cerit, Ethem Turgay, Yalçin, Mehmet Muhittin, Ӧzkan, Çiğdem, Aktürk, Müjde, Altinova, Alev Eroğlu, Akdemir, Ümit Ӧzgür, Akin, Murat, Arslan, Emre, Karakoç, Ayhan, Çimen, Ali Riza, Çakir, Nuri
Format:	Journal Article
Language:	English
Published:	Brazil Sociedade Brasileira de Endocrinologia e Metabologia 01-10-2018 Brazilian Society of Endocrinology and Metabolism
Subjects:	Adult Aged Carcinoma, Papillary - diagnostic imaging Carcinoma, Papillary - secondary Carcinoma, Papillary - surgery Differentiated thyroid cancer Female guided intraoperative scintigraphic tumor targeting Humans Lymph Node Excision - methods Lymph Nodes - diagnostic imaging Lymph Nodes - pathology Lymph Nodes - surgery Lymphatic Metastasis Male Middle Aged Neck - diagnostic imaging Neck - pathology Neck - surgery Neoplasm Recurrence, Local Original radio-guided occult lesion localization Radiography, Interventional Radionuclide Imaging - methods recurrent thyroid carcinoma Reproducibility of Results Retrospective Studies Thyroid Neoplasms - pathology Treatment Outcome
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Summary:	Our aim was to present our experiences related to performing neck surgery using the guided intraoperative scintigraphic tumor targeting (GOSTT) procedure for patients who had locally recurrent or persistent differentiated thyroid cancer (DTC) and who had undergone previous thyroid surgery. We retrospectively evaluated 11 patients who had locally recurrent or persistent DTC, who had undergone previous surgery, and for whom reoperation was planned for metastatic cervical lymph nodes (LNs). We performed the neck surgery using the GOSTT procedure on all patients and at a single academic institution. The 11 patients had a total of 26 LNs, as marked with a radiotracer, and those LNs' mean size was 14.7 ± 8.2 mm (range: 5-34 mm). Histopathological examinations revealed DTC metastasis in all 26 of the preoperatively marked LNs. Of the 11 patients, only one needed a reoperation in the neck; she had another successful surgery (also using the GOSTT procedure). In the evaluation of the patients' final status, all were disease-free in their necks. There also were no GOSTT-associated postoperative complications. The GOSTT procedure is a useful, successful, inexpensive, and comfortable procedure for marking and mapping metastatic LNs, especially in DTC patients who have undergone previous surgery.
ISSN:	2359-3997 2359-4292 2359-4292
DOI:	10.20945/2359-3997000000068