Search Results - "Akbuğa, J"
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The use of fucosphere in the treatment of dermal burns in rabbits
Published in European journal of pharmaceutics and biopharmaceutics (01-05-2008)“…The aim of this study was to prepare a new microsphere (fucosphere) system based on polyion complexation of fucoidan with chitosan, and to evaluate its…”
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2
Evaluation of antisense oligonucleotide loaded chitosan nanoparticles; characterization and antisense effect
Published in Pharmazie (01-12-2009)“…The objective of this study was to investigate the effect of different formulation parameters [i.e. molecular weight and concentration of chitosan,…”
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3
Complement system's role in cancer and its therapeutic potential in ovarian cancer
Published in Scandinavian journal of immunology (01-07-2018)“…Cancer immunotherapy is a strong candidate for the long‐awaited new edition to standard cancer therapies. For an effective immunotherapy, it is imperative to…”
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In vitro silencing effect of chitosan nanoplexes containing siRNA expressing vector targeting VEGF in breast cancer cell lines
Published in Pharmazie (01-12-2010)“…Small interferring RNA (siRNA) is a powerful tool for controlling cellular processes of gene silencing at post-transcriptional level due to its high…”
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Tacrolimus-Eluting Suture Inhibits Neointimal Hyperplasia: An Experimental In Vivo Study in Rats
Published in European journal of vascular and endovascular surgery (01-03-2017)“…Neointimal hyperplasia (NIH) remains one of the leading causes of graft failure after vascular anastomoses. Cytotoxic drugs, such as rapamycin and tacrolimus,…”
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6
Fucosphere-New microsphere carriers for peptide and protein delivery: Preparation and in vitro characterization
Published in Journal of microencapsulation (01-08-2006)“…Purpose: Fucoidan is a complex polysaccharide containing sugars and high amounts of sulphate derived from marine brown algaes. In this study, a new…”
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Effects of different forms of chitosan on intercellular junctions of mouse fibroblasts in vitro
Published in Biotechnic & histochemistry (02-01-2016)“…Chitosan is a linear polysaccharide that has many biomedical applications. We compared the effects of chitosan, in both solution and membranous form, on…”
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Increased in vitro Cell Proliferation by Chitosan/pGM-CSF Complexes
Published in Indian journal of pharmaceutical sciences (01-03-2011)“…Granulocyte macrophage colony stimulating factor, a potent hematopoietic cytokine, has been shown to stimulate production of white blood cells following…”
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Release characteristics of chitosan treated alginate beads: II. Sustained release of a low molecular drug from chitosan treated alginate beads
Published in Journal of microencapsulation (01-11-1999)“…The aim of this paper was to investigate the possible applicability of chitosan treated alginate beads as a controlled release system of small molecular drugs…”
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10
Some factors affecting properties and dissolution behavior of tableted furosemide microspheres
Published in Pharmazie (01-02-1992)“…Furosemide (1) microspheres prepared by using Eudragit RS (1:4 and 1:2 drug:polymer ratios) were tableted. Microspheres were compressed with or without…”
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Release characteristics of chitosan treated alginate beads: I. Sustained release of a macromolecular drug from chitosan treated alginate beads
Published in Journal of microencapsulation (1999)“…Alginate and chitosan treated alginate beads were prepared and compared as an oral controlled release system for macromolecular drugs. Dextran (M.W. 70000) was…”
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12
Effect of formulation variables on cis-platin loaded chitosan microsphere properties
Published in Journal of microencapsulation (01-11-1999)“…Chitosan microspheres containing cis-platin were prepared using a w/o emulsion system. Variables important for microsphere properties were investigated: these…”
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13
Chitosan beads for the delivery of salmon calcitonin: Preparation and release characteristics
Published in International journal of pharmaceutics (05-04-1996)“…Salmon calcitonin (sCT)-loaded chitosan beads were prepared by dropping a drug containing solution of chitosan into tripolyphosphate solution. The droplets…”
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14
Controlled release of piroxicam from chitosan beads
Published in International journal of pharmaceutics (06-07-1995)“…Piroxicam-loaded chitosan gel beads were prepared by dropping drug-containing solution of chitosan into tripolyphosphate solutions. The droplets…”
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15
5-Fluorouracil-loaded chitosan microspheres: preparation and release characteristics
Published in Journal of microencapsulation (1996)“…Cross-linked chitosan microspheres containing 5-Fluorouracil (5-FU) were prepared. Variables believed to be important for microsphere properties were examined;…”
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16
The inhibitory effect of liposome-encapsulated indomethacin on inflammation and platelet aggregation
Published in Journal of pharmacy and pharmacology (01-01-1988)“…A comparison has been made between liposome-encapsulated and free indomethacin for their anti-inflammatory activities in the carrageenan paw oedema test in…”
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Effect of Drug Properties on Physical and Release Characteristics of Eudragit Microspheres Prepared by Spherical Crystallization Technique
Published in Drug development and industrial pharmacy (1997)“…Abstract Ten compounds having different solubilities and molecular weights were evaluated for incorporation into Eudragit microspheres using the spherical…”
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18
Tacrolimus-Eluting Suture Inhibits Neointimal Hyperplasia: An Experimental I n Vivo Study in Rats
Published in European journal of vascular and endovascular surgery (2016)“…Objective/Background Neointimal hyperplasia (NIH) remains one of the leading causes of graft failure after vascular anastomoses. Cytotoxic drugs, such as…”
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19
Local delivery of chitosan/VEGF siRNA nanoplexes reduces angiogenesis and growth of breast cancer in vivo
Published in Nucleic acid therapeutics (01-02-2012)“…Vascular endothelial growth factor (VEGF) is the important angiogenic factor associated with tumor growth and metastasis in a wide variety of solid tumors. The…”
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Preparation and in vitro transfection efficiency of chitosan microspheres containing plasmid DNA:poly(L-lysine) complexes
Published in Journal of pharmacy & pharmaceutical sciences (01-09-2003)“…Studies on DNA complexes with cationic polymers are prompted by the search for nonviral DNA carriers for gene therapy. Among them, poly(L-Lysine) (PLL) has…”
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