Search Results - "Akbayir, Ece"
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Cerebrospinal fluid level of phosphorylated neurofilament heavy chain is higher in converting clinically isolated syndrome and correlates with CAMP response element-binding protein concentration
Published in Neurological sciences and neurophysiology (01-10-2021)“…Introduction: Prevision of conversion from clinically isolated syndrome (CIS) to multiple sclerosis (MS) is required to avoid unnecessary use of…”
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Sleep disturbance and cognitive decline in multiple sclerosis patients with isolated optic neuritis as the first demyelinating event
Published in International ophthalmology (2020)“…Purpose Multiple sclerosis (MS) patients whose first demyelinating event is optic neuritis have been claimed to display a milder disease course and reduced…”
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Altered Cerebrospinal Fluid Neurofilament Light Chain but Not Neurogranin Levels Are Associated with Response to Ocrelizumab Treatment in Relapsing-Remitting Multiple Sclerosis: A Preliminary Study
Published in European neurology (2024)“…Ocrelizumab is a CD20-targeting monoclonal antibody used for treatment of multiple sclerosis (MS). Serum and cerebrospinal fluid (CSF) neurofilament light…”
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Disease activity in chronic inflammatory demyelinating polyneuropathy: association between circulating B-cell subsets, cytokine levels, and clinical outcomes
Published in Clinical and experimental immunology (09-01-2024)“…Chronic inflammatory demyelinating polyneuropathy (CIDP), a common and treatable autoimmune neuropathy, is frequently misdiagnosed. The aim of this study is to…”
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Expression of Akt1 and p-Akt1 in peripheral T cell subsets of multiple sclerosis patients
Published in Acta neurologica Belgica (01-12-2021)“…Multiple sclerosis is an autoimmune disorder induced by the infiltration of autoreactive immune cells into the central nervous system. Akt/PKB signaling…”
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Adaptive immunity cells are differentially distributed in the peripheral blood of glycine receptor antibody-positive patients with focal epilepsy of unknown cause
Published in Epilepsy research (01-02-2021)“…•GlyR-Ab positive patients exhibited significantly increased CD3+CD4+CD25highregulatory T (Treg) cells and CD3+CD4+CD25highCD127low/- Treg cells and relatively…”
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Enhanced NLRP3 and DEFA1B Expression During the Active Stage of Parenchymal Neuro-Behçet's Disease
Published in In vivo (Athens) (01-09-2019)“…Neurological symptoms (neuro-Behçet's disease; NBD) occur in a fraction of Behçet's disease (BD) patients and often present with parenchymal brain lesions and…”
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CSF levels of HoxB3 and YKL-40 may predict conversion from clinically isolated syndrome to relapsing remitting multiple sclerosis
Published in Multiple sclerosis and related disorders (01-02-2021)“…•Our findings introduce and propose potential T cell activity modifier, HoxB3, as a candidate molecule with biomarker capacity for disease conversion and…”
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Phosphorylated Neurofilament Heavy Chain (pNFH) in Clinically Isolated Syndrome and Multiple Sclerosis
Published in Noro-Psikiyatri Arsivi (2021)Get full text
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Peripheral blood B cell subset ratios and expression levels of B cell-associated genes are altered in benign multiple sclerosis
Published in Multiple sclerosis and related disorders (01-07-2021)“…•Sleep and cognitive functions are equally impaired in benign (BMS) and non-benign MS (NBMS).•Memory B cells are reduced and regulatory B cells are increased…”
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Serum 3-phenyllactic acid level is reduced in benign multiple sclerosis and is associated with effector B cell ratios
Published in Multiple sclerosis and related disorders (01-12-2022)“…•Bacterial derived D-PLA is significantly reduced in benign MS.•Fingolimod resistance in MS is associated with high PLA levels.•High PLA levels in MS correlate…”
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Cerebrospinal fluid level of neurofilament light chain is associated with increased disease activity in neuro-Behçet's disease
Published in Turkish journal of medical sciences (01-01-2022)“…Clinical exacerbations characterized with neurological symptoms are observed in around 10% of Behçet's disease (BD) patients and may culminate in severe…”
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Klinik İzole Sendrom ve Multipl Sklerozda Fosforile Nörofilament Ağır Zinciri (pNFH)
Published in Noro-Psikiyatri Arsivi (01-12-2021)“…Conflict of Interest: The authors have no potential conflicts of interest to disclose. Kuhle J, Barro C, Andreasson U, Derfuss T, Lindberg R, Sandelius Å,…”
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Microarray Analysis Indicates Altered Expression Levels of B Cell Genes in Benign Multiple Sclerosis (P2.2-078)
Published in Neurology (09-04-2019)“…Abstract only…”
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Distribution of peripheral blood mononuclear cell subtypes in patients with West syndrome: Impact of synacthen treatment
Published in Immunology letters (01-09-2023)“…•WS patients show increased plasma and cytotoxic T cells in peripheral blood.•Regulatory T and B cell populations are not altered in WS.•Synacthen treatment…”
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Serum orexin-A levels are associated with disease progression and motor impairment in multiple sclerosis
Published in Neurological sciences (01-05-2019)“…Objective Diencephalon is frequently affected in multiple sclerosis (MS), and lesions of this region are associated with increased disability. Orexin-A and…”
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Cytokine-chemokine and cognitive profile of multiple sclerosis patients with predominant optic nerve and spinal cord involvement
Published in The journal of spinal cord medicine (04-05-2021)“…Context/Objective: Clinical disease activity in multiple sclerosis (MS) may manifest as predominant involvement of optic nerves and spinal cord, as exemplified…”
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Fingolimod impairs inactivated vaccine (CoronaVac)-induced antibody response to SARS-CoV-2 spike protein in persons with multiple sclerosis
Published in Multiple sclerosis and related disorders (01-02-2022)“…: The impact of disease-modifying treatments on humoral response induced by inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines…”
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