Search Results - "Akbari, Mohammad R"
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Liquid biopsy in breast cancer: A comprehensive review
Published in Clinical genetics (01-06-2019)“…Breast cancer is the most common cancer among women worldwide. Due to its complexity in nature, effective breast cancer treatment can encounter many…”
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2
Potential clinical utility of liquid biopsies in ovarian cancer
Published in Molecular cancer (11-05-2022)“…Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One of the main challenges in the management of OC is the late clinical presentation…”
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3
CA125 and Ovarian Cancer: A Comprehensive Review
Published in Cancers (11-12-2020)“…Ovarian cancer is the second most lethal gynecological malignancy. The tumour biomarker CA125 has been used as the primary ovarian cancer marker for the past…”
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4
A Single nucleotide polymorphism in the ALDH2 gene modifies the risk of esophageal squamous cell carcinoma in BRCA2 p.K3326 carriers
Published in PloS one (09-11-2023)“…Esophageal squamous cell carcinoma (ESCC) has a very high incidence rate in northeastern Iran. Our team previously reported the BReast CAncer gene 2 ( BRCA2 )…”
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5
Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis
Published in The lancet oncology (01-06-2015)“…Summary Background Mutations in PALB2 predispose to breast cancer, but the effect on prognosis of carrying a PALB2 mutation has not been ascertained. We aimed…”
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Evaluating the Utility of ctDNA in Detecting Residual Cancer and Predicting Recurrence in Patients with Serous Ovarian Cancer
Published in International journal of molecular sciences (01-09-2023)“…Ovarian cancer has a high case fatality rate, but patients who have no visible residual disease after surgery have a relatively good prognosis. The presence of…”
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Immune infiltration, aggressive pathology, and poor survival outcomes in RECQL helicase deficient breast cancers
Published in Neoplasia (New York, N.Y.) (01-01-2024)“…RECQL is essential for genomic stability. Here, we evaluated RECQL in 449 pure ductal carcinomas in situ (DCIS), 152 DCIS components of mixed DCIS/invasive…”
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8
Genetic susceptibility to hereditary non-medullary thyroid cancer
Published in Hereditary cancer in clinical practice (07-03-2022)“…Non-medullary thyroid cancer (NMTC) is the most common type of thyroid cancer. With the increasing incidence of NMTC in recent years, the familial form of the…”
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9
Optimizing shipment, ordering and pricing policies in a two-stage supply chain with price-sensitive demand
Published in Transportation research. Part E, Logistics and transportation review (01-07-2009)“…In this paper we focus on a two-stage supply chain consisting of one vendor and one buyer. We develop an integrated production–inventory–marketing model to…”
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10
PPM1D Mutations in Circulating White Blood Cells and the Risk for Ovarian Cancer
Published in JNCI : Journal of the National Cancer Institute (01-01-2014)“…We compared the frequency of PPM1D mutation in the white blood cells from 1295 ovarian cancer case patients and 834 control subjects. We found a truncating…”
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Genetic Overview of Syndactyly and Polydactyly
Published in Plastic and reconstructive surgery. Global open (01-11-2017)“…Syndactyly and polydactyly—respectively characterized by fused and supernumerary digits—are among the most common congenital limb malformations, with…”
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A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene
Published in PLoS genetics (30-08-2019)“…Pancreatic adenocarcinoma (PC) is a lethal malignancy that is familial or associated with genetic syndromes in 10% of cases. Gene-based surveillance strategies…”
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13
High Expression of RECQL Protein in ER-Positive Breast Tumours Is Associated With a Better Survival
Published in Frontiers in oncology (31-05-2022)“…Background RECQL (also known as RECQ1 and RECQL1) is a gene of recent interest in breast cancer and an association between high levels of RECQL protein in…”
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14
Investigating the causal role of MRE11A p.E506 in breast and ovarian cancer
Published in Scientific reports (28-01-2021)“…The nuclease MRE11A is often included in genetic test panels for hereditary breast and ovarian cancer (HBOC) due to its BRCA1-related molecular function in the…”
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15
A rewarding-punishing coordination mechanism based on Trust in a divergent supply chain
Published in European journal of operational research (01-11-2013)“…•Introducing trust as a non-pecuniary factor to develop coordination mechanisms.•Formulating the model as a non-linear constrained optimization…”
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The APOBEC3B c.783delG Truncating Mutation Is Not Associated with an Increased Risk of Breast Cancer in the Polish Population
Published in Genes (24-06-2023)“…The gene belongs to a cluster of DNA-editing enzymes on chromosome 22 and encodes an activation-induced cytidine deaminase. A large deletion of was associated…”
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Molecular intrinsic versus clinical subtyping in breast cancer: A comprehensive review
Published in Clinical genetics (01-05-2021)“…Breast cancer is a heterogeneous disease manifesting diversity at the molecular, histological and clinical level. The development of breast cancer…”
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Genetic testing women with newly diagnosed breast cancer: What criteria are the most predictive of a positive test?
Published in Cancer medicine (Malden, MA) (01-03-2023)“…Background Knowledge of pathogenic variants in cancer‐predisposing genes is important when making breast cancer treatment decisions, but genetic testing is not…”
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An appraisal of genetic testing for prostate cancer susceptibility
Published in NPJ precision oncology (22-06-2022)“…Most criteria for genetic testing for prostate cancer susceptibility require a prior diagnosis of prostate cancer, in particular cases with metastatic disease…”
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Correlation between germline mutations in MMR genes and microsatellite instability in ovarian cancer specimens
Published in Familial cancer (01-07-2017)“…A high proportion of ovarian cancers from women who carry germline mutations in mismatch repair (MMR) genes demonstrate microsatellite instability (MSI). The…”
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