Search Results - "Akbaba, Tayfun Hilmi"
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Potential of miRNAs to predict and treat inflammation from the perspective of Familial Mediterranean Fever
Published in Inflammation research (01-11-2019)“…Aim microRNAs (miRNAs) are small noncoding RNAs that play critical roles in physiological networks by regulating host genome expression at the…”
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Familial Mediterranean fever-related miR-197-3p targets IL1R1 gene and modulates inflammation in monocytes and synovial fibroblasts
Published in Scientific reports (12-01-2021)“…Familial Mediterranean fever (FMF); is an autosomal recessively inherited autoinflammatory disease caused by the mutations in the Mediterranean Fever ( MEFV )…”
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Characterization of serum extracellular vesicles and their differential level of miR-197-3p in familial Mediterranean fever patients
Published in Nucleosides, nucleotides & nucleic acids (2024)“…EVs and EV-miRNAs can be identified in FMF patients' sera. Serum EV-miR-197-3p is dysregulated in FMF patients. Serum EV-miR-197-3p might have both diagnostic…”
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Anti-LAMP-2 Antibody Seropositivity in Children with Primary Systemic Vasculitis Affecting Medium- and Large-Sized Vessels
Published in International journal of molecular sciences (01-04-2024)“…Chronic primary systemic vasculitis (PSV) comprises a group of heterogeneous diseases that are broadly classified by affected blood vessel size, clinical…”
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Human Ace D/I Polymorphism Could Affect the Clinicobiological Course of COVID-19
Published in Journal of the renin-angiotensin-aldosterone system (01-01-2021)“…Introduction. The coronavirus disease 2019 (COVID-19), that is caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), has spread rapidly…”
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Acute stroke in familial Mediterranean fever: An analysis of 23 new cases and systematic review of the literature
Published in International journal of rheumatic diseases (01-04-2023)“…Objective The nature of neurovascular involvement in cases of familial Mediterranean fever (FMF) has not been adequately clarified. Methods and Patients…”
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InflammamiRs in focus: Delivery strategies and therapeutic approaches
Published in The FASEB journal (15-03-2024)“…microRNAs (miRNAs) are small non‐protein‐coding RNAs which are essential regulators of host genome expression at the post‐transcriptional level. There is…”
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Epigenetics for Clinicians from the Perspective of Pediatric Rheumatic Diseases
Published in Current rheumatology reports (01-08-2020)“…Purpose of Review Epigenetics is the study of inherited phenotype changes that do not involve in alteration of DNA sequence. Epigenetic regulation can be…”
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The pyrin inflammasome aggravates inflammatory cell migration in patients with familial Mediterranean fever
Published in Pediatric research (01-05-2022)“…Background Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by pathogenic variants of the MEFV gene, which encodes pyrin. Leukocyte…”
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Mitochondrial Dysfunction in Cyanotic Congenital Heart Disease: A Promising Therapeutic Approach for the Future
Published in Pediatric cardiology (01-12-2022)“…Congenital heart disease (CHD) is one of the most specific and yet challenging fields of heart surgery. Apart from the known clinical approaches, including…”
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Dysregulation of miRNA-30e-3p targeting IL-1β in an international cohort of systemic autoinflammatory disease patients
Published in Journal of molecular medicine (Berlin, Germany) (01-06-2023)“…Autoinflammation is the standard mechanism seen in systemic autoinflammatory disease (SAID) patients. This study aimed to investigate the effect of a candidate…”
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Drug metabolism and inflammation related distinct miRNA signature of colchicine resistant familial Mediterranean fever patients
Published in International immunopharmacology (01-11-2023)“…•miRNAs have an important potential as candidate biomarkers of colchicine resistance seen in familial Mediterranean fever.•25 differentially expressed miRNAs…”
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Behçet’s syndrome: recent advances to aid diagnosis
Published in Clinical and experimental medicine (01-12-2023)“…Behçet’s syndrome is a recurring inflammatory multiorgan disorder affecting the skin, mucosa, eyes, joints, stomach, and central nervous system. Behçet’s…”
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Analysis of polymorphisms in the colchicine binding site of tubulin in colchicine-resistant familial Mediterranean fever patients
Published in Molecular biology reports (01-11-2020)“…Familial Mediterranean fever is a hereditary autoinflammatory syndrome. The typical treatment for the disease is colchicine. However, a subset of patients are…”
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Biologia Futura: the importance of 3D organoids-a new approach for research on neurological and rare diseases
Published in Biologia futura (01-09-2021)“…3D cell cultures and organoid approach are increasingly being used for basic research and drug discovery of several diseases. Recent advances in these…”
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