Search Results - "Akay, Yasemin M."

The Role of Neurons in Human Health and Disease by Akay, Yasemin M

“…Neurons are the functional units of the nervous system [...]…”
Get full text

Investigating the Modulation of the VTA Neurons in Nicotine-Exposed Pups during Early Maturation Using Optogenetics by Ganaway, Austin, Sunaga, Yoshinori, Ohta, Yasumi, Ohta, Jun, Akay, Metin, Akay, Yasemin M

“…Advancing the understanding of the relationship between perinatal nicotine addiction and the reward mechanism of the brain is crucial for uncovering and…”
Get full text

Lightweight Neural Network for Sleep Posture Classification Using Pressure Sensing Mat at Various Sensor Densities by Wu, Shaonan, Diao, Haikang, Feng, Yi, Zhang, Yiyuan, Chen, Hongyu, Akay, Yasemin M., Akay, Metin, Chen, Chen, Chen, Wei

“…Recently, pressure-sensing mats have been widely used to capture static and dynamic pressure over sleep for posture recognition. Both a full-size mat with a…”
Get full text

Prenatal nicotine exposure alters gene expression profiles of neurons in the sub-regions of the VTA during early postnatal development by McGill, Lindsey D., Avci, Naze G., Kazemi, Tina, Sunaga, Yoshinori, Akay, Yasemin M., Akay, Metin

“…Brain growth occurs during the first 2 weeks of postnatal development in rats. This developmental period is equivalent to the third trimester of human…”
Get full text

Astrocytes Decreased the Sensitivity of Glioblastoma Cells to Temozolomide and Bay 11-7082 by Pustchi, Sadaf E, Avci, Naze G, Akay, Yasemin M, Akay, Metin

“…Glioblastoma multiforme (GBM) is the most common malignant type of astrocytic tumors. GBM patients have a poor prognosis with a median survival of…”
Get full text

Investigating the Influence of Morphine and Cocaine on the Mesolimbic Pathway Using a Novel Microimaging Platform by Ganaway, Austin, Tatsuta, Kousuke, Castillo, Virgil Christian Garcia, Okada, Ryoma, Sunaga, Yoshinori, Ohta, Yasumi, Ohta, Jun, Ohsawa, Masahiro, Akay, Metin, Akay, Yasemin M

“…Dopamine (DA)’s relationship with addiction is complex, and the related pathways in the mesocorticolimbic system are used to deliver DA, regulating both…”
Get full text

Automatic Upper-Limb Brunnstrom Recovery Stage Evaluation via Daily Activity Monitoring by Meng, Long, Jiang, Xinyu, Qin, Haibo, Fan, Jiahao, Zeng, Zheng, Chen, Chen, Zhang, Anjing, Dai, Chenyun, Wu, Xiaomei, Akay, Yasemin M., Akay, Metin, Chen, Wei

“…Motor function assessment is crucial for post-stroke rehabilitation. Conventional evaluation methods are subjective, heavily depending on the experience of…”
Get full text

Investigating the effects of chronic perinatal alcohol and combined nicotine and alcohol exposure on dopaminergic and non-dopaminergic neurons in the VTA by Kazemi, Tina, Huang, Shuyan, Avci, Naze G., Akay, Yasemin M., Akay, Metin

“…The ventral tegmental area (VTA) is the origin of dopaminergic neurons and the dopamine (DA) reward pathway. This pathway has been widely studied in addiction…”
Get full text

Investigating the Influence of GABA Neurons on Dopamine Neurons in the Ventral Tegmental Area Using Optogenetic Techniques by Ohta, Yasumi, Murakami, Takaaki E, Kawahara, Mamiko, Haruta, Makito, Takehara, Hironari, Tashiro, Hiroyuki, Sasagawa, Kiyotaka, Ohta, Jun, Akay, Metin, Akay, Yasemin M

“…Dopamine (DA) is the key regulator of reward behavior. The DA neurons in the ventral tegmental area (VTA) and their projection areas, which include the…”
Get full text

Multi-Region Microdialysis Imaging Platform Revealed Dorsal Raphe Nucleus Calcium Signaling and Serotonin Dynamics during Nociceptive Pain by Akbar, Latiful, Castillo, Virgil Christian Garcia, Olorocisimo, Joshua Philippe, Ohta, Yasumi, Kawahara, Mamiko, Takehara, Hironari, Haruta, Makito, Tashiro, Hiroyuki, Sasagawa, Kiyotaka, Ohsawa, Masahiro, Akay, Yasemin M, Akay, Metin, Ohta, Jun

“…In this research, we combined our ultralight micro-imaging device for calcium imaging with microdialysis to simultaneously visualize neural activity in the…”
Get full text

Monitoring neural activities in the VTA in response to nicotine intake using a novel implantable microimaging device by Sunaga, Yoshinori, Ohta, Yasumi, Akay, Yasemin M, Ohta, Jun, Akay, Metin

“…Measurements of the deep brain area of rodents has been one of the most important methods to study deep brain activities, in part due to limited access of this…”
Get full text

Comparison between dopaminergic and non-dopaminergic neurons in the VTA following chronic nicotine exposure during pregnancy by Keller, Renee F., Kazemi, Tina, Dragomir, Andrei, Akay, Yasemin M., Akay, Metin

“…Exposure to nicotine during pregnancy through maternal smoking or nicotine replacement therapy is associated with adverse birth outcomes as well as several…”
Get full text

Deep Learning Classification of Systemic Sclerosis Skin Using the MobileNetV2 Model by Akay, Metin, Du, Yong, Sershen, Cheryl L., Wu, Minghua, Chen, Ting Y., Assassi, Shervin, Mohan, Chandra, Akay, Yasemin M.

“…Goal: Systemic sclerosis (SSc) is a rare autoimmune, systemic disease with prominent fibrosis of skin and internal organs. Early diagnosis of the disease is…”
Get full text

Selecting Relevant Genes From Microarray Datasets Using a Random Forest Model by Xia, Hui, Akay, Yasemin M., Akay, Metin

“…Recent studies have demonstrated microarray expression data can be used to identify gene regulatory pathways. However, one of the major challenges is to…”
Get full text

Monitoring Neuronal Dynamics in the Ventral Tegmental Area Using an Implantable Microimaging Device With Microdialysis System by Sunaga, Yoshinori, Ohta, Yasumi, Murakami, Takaaki E, Akay, Yasemin M., Ohta, Jun, Akay, Metin

“…To monitor dopamine neural activities in the ventral tegmental area (VTA) in response to nicotine, we designed a dopamine platform based on a microimaging…”
Get full text

Targeted Sensitization of Glioblastoma Multiforme Using AAAPT Technology by Mendieta, Megan, Avci, Naze G., Pandurangi, Raghu, Akay, Yasemin M., Akay, Metin

“…Glioblastoma Multiforme (GBM) is the most malignant type of all brain tumors. Current GBM treatment options include surgery, followed by radiation and…”
Get full text

Multifunctional Implantable Device for Simultaneous Optical and Electrophysiological Measurements by Naganuma, Kyosuke, Ohta, Yasumi, Murakami, Takaaki E., Okada, Ryoma, Guinto, Mark Christian, Takehara, Hironari, Haruta, Makito, Tashiro, Hiroyuki, Sasagawa, Kiyotaka, Sunaga, Yoshinori, Akay, Yasemin M., Akay, Metin, Ohta, Jun

“…In neuroscience, it is crucial to clarify the relationship between single-cell activity and neural network structure to understand brain neural activity. To…”
Get full text

Micro-LED Array-Based Photo-Stimulation Devices for Optogenetics in Rat and Macaque Monkey Brains by Ohta, Yasumi, Guinto, Mark Christian, Tokuda, Takashi, Kawahara, Mamiko, Haruta, Makito, Takehara, Hironari, Tashiro, Hiroyuki, Sasagawa, Kiyotaka, Onoe, Hirotaka, Yamaguchi, Reona, Koshimizu, Yoshinori, Isa, Kaoru, Isa, Tadashi, Kobayashi, Kenta, Akay, Yasemin M., Akay, Metin, Ohta, Jun

“…Optogenetics is a powerful tool for controlling biological functions using light. Optical fibers have been extensively utilized in optical stimulation devices…”
Get full text

The Influence of Human Astrocyte-Conditioned Media on Glioblastoma Multiforme Response to Temozolomide and Bay 11-7082 by Pustchi, Sadaf E., Waits, Charlotte Mae K., Avci, Naze Gul, Mcgill, Lindsey, Akay, Yasemin M., Akay, Metin

“…Glioblastoma Multiforme (GBM) cells interact with a complex, heterogeneous tumor microenvironment (TME). This TME consists of astrocytes, endothelial cells,…”
Get full text

Processes for Designing Innovative Biomedical Hardware to Use In Space and on Earth by Kimia, Seyedmadani, Keith, Tucker A., Baraquiel, Reyna, M.Yasemin, Akay, Metin, Akay, Jennifer, Fogarty A.

“…The new era of space exploration is increasing the astronaut's number and diversity in low orbit and beyond. The influx of such a diverse crew population will…”
Get full text