Search Results - "Akay, Turgay"

Stumbling corrective reaction elicited by mechanical and electrical stimulation of the saphenous nerve in walking mice by Mayer, William Paganini, Akay, Turgay

“…The ability to walk around in a natural environment requires the capacity to cope with unexpected obstacles that may disrupt locomotion. One such mechanism is…”
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Fractal analysis of muscle activity patterns during locomotion: pitfalls and how to avoid them by Santuz, Alessandro, Akay, Turgay

“…Despite the lack of consensus on how to perform fractal analysis of physiological time series, many studies rely on this technique. Here, we shed light on the…”
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Degradation of mouse locomotor pattern in the absence of proprioceptive sensory feedback by Akay, Turgay, Tourtellotte, Warren G., Arber, Silvia, Jessell, Thomas M.

“…Significance Terrestrial locomotion is thought to be generated by the actions of a circuit of interconnected interneurons (central pattern generator) in the…”
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Relative Contribution of Proprioceptive and Vestibular Sensory Systems to Locomotion: Opportunities for Discovery in the Age of Molecular Science by Akay, Turgay, Murray, Andrew J

“…Locomotion is a fundamental animal behavior required for survival and has been the subject of neuroscience research for centuries. In terrestrial mammals, the…”
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Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster by Mendes, César S, Bartos, Imre, Akay, Turgay, Márka, Szabolcs, Mann, Richard S

“…Coordinated walking in vertebrates and multi-legged invertebrates [corrected] such as Drosophila melanogaster requires a complex neural network coupled to…”
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Modular organization of murine locomotor pattern in the presence and absence of sensory feedback from muscle spindles by Santuz, Alessandro, Akay, Turgay, Mayer, William P., Wells, Tyler L., Schroll, Arno, Arampatzis, Adamantios

“…Key points Locomotion on land and in water requires the coordination of a great number of muscle activations and joint movements. Constant feedback about the…”
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Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration by Kaplan, Artem, Spiller, Krista J, Towne, Christopher, Kanning, Kevin C, Choe, Ginn T, Geber, Adam, Akay, Turgay, Aebischer, Patrick, Henderson, Christopher E

“…Selective neuronal loss is the hallmark of neurodegenerative diseases. In patients with amyotrophic lateral sclerosis (ALS), most motor neurons die but those…”
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Spinal microcircuits comprising dI3 interneurons are necessary for motor functional recovery following spinal cord transection by Bui, Tuan V, Stifani, Nicolas, Akay, Turgay, Brownstone, Robert M

“…The spinal cord has the capacity to coordinate motor activities such as locomotion. Following spinal transection, functional activity can be regained, to a…”
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A Cluster of Cholinergic Premotor Interneurons Modulates Mouse Locomotor Activity by Zagoraiou, Laskaro, Akay, Turgay, Martin, James F., Brownstone, Robert M., Jessell, Thomas M., Miles, Gareth B.

“…Mammalian motor programs are controlled by networks of spinal interneurons that set the rhythm and intensity of motor neuron firing. Motor neurons have long…”
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Balance Control Mediated by Vestibular Circuits Directing Limb Extension or Antagonist Muscle Co-activation by Murray, Andrew J., Croce, Katherine, Belton, Timothy, Akay, Turgay, Jessell, Thomas M.

“…Maintaining balance after an external perturbation requires modification of ongoing motor plans and the selection of contextually appropriate muscle activation…”
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Role of muscle spindle feedback in regulating muscle activity strength during walking at different speed in mice by Mayer, William P, Murray, Andrew J, Brenner-Morton, Susan, Jessell, Thomas M, Tourtellotte, Warren G, Akay, Turgay

“…Terrestrial animals increase their walking speed by increasing the activity of the extensor muscles. However, the mechanism underlying how this speed-dependent…”
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V3 Spinal Neurons Establish a Robust and Balanced Locomotor Rhythm during Walking by Zhang, Ying, Narayan, Sujatha, Geiman, Eric, Lanuza, Guillermo M., Velasquez, Tomoko, Shanks, Bayle, Akay, Turgay, Dyck, Jason, Pearson, Keir, Gosgnach, Simon, Fan, Chen-Ming, Goulding, Martyn

“…A robust and well-organized rhythm is a key feature of many neuronal networks, including those that regulate essential behaviors such as circadian…”
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Patterns of Spinal Sensory-Motor Connectivity Prescribed by a Dorsoventral Positional Template by Sürmeli, Gülşen, Akay, Turgay, Ippolito, Gregory C., Tucker, Philip W., Jessell, Thomas M.

“…Sensory-motor circuits in the spinal cord are constructed with a fine specificity that coordinates motor behavior, but the mechanisms that direct sensory…”
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Circuits for Grasping: Spinal dI3 Interneurons Mediate Cutaneous Control of Motor Behavior by Bui, Tuan V., Akay, Turgay, Loubani, Osama, Hnasko, Thomas S., Jessell, Thomas M., Brownstone, Robert M.

“…Accurate motor performance depends on the integration in spinal microcircuits of sensory feedback information. Hand grasp is a skilled motor behavior known to…”
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Freely Behaving Mice Can Brake and Turn During Optogenetic Stimulation of the Mesencephalic Locomotor Region by van der Zouwen, Cornelis Immanuel, Boutin, Joël, Fougère, Maxime, Flaive, Aurélie, Vivancos, Mélanie, Santuz, Alessandro, Akay, Turgay, Sarret, Philippe, Ryczko, Dimitri

“…A key function of the mesencephalic locomotor region (MLR) is to control the speed of forward symmetrical locomotor movements. However, the ability of freely…”
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ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control by Khan, Mudassar N, Cherukuri, Pitchaiah, Negro, Francesco, Rajput, Ashish, Fabrowski, Piotr, Bansal, Vikas, Lancelin, Camille, Lee, Tsung-I, Bian, Yehan, Mayer, William P, Akay, Turgay, Müller, Daniel, Bonn, Stefan, Farina, Dario, Marquardt, Till

“…The ability of terrestrial vertebrates to effectively move on land is integrally linked to the diversification of motor neurons into types that generate muscle…”
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Kinematic gait parameters are highly sensitive measures of motor deficits and spinal cord injury in mice subjected to experimental autoimmune encephalomyelitis by Fiander, Maximillan D.J., Stifani, Nicolas, Nichols, Matthew, Akay, Turgay, Robertson, George S.

“…•Kinematic gait analyses identified movement deficits before the onset of clinical signs in mice subjected to experimental autoimmune encephalomyelitis…”
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Are mice good models for human neuromuscular disease? Comparing muscle excursions in walking between mice and humans by Hu, Xiao, Charles, James P, Akay, Turgay, Hutchinson, John R, Blemker, Silvia S

“…The mouse is one of the most widely used animal models to study neuromuscular diseases and test new therapeutic strategies. However, findings from successful…”
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Control of Mammalian Locomotion by Somatosensory Feedback by Frigon, Alain, Akay, Turgay, Prilutsky, Boris I

“…When animals walk overground, mechanical stimuli activate various receptors located in muscles, joints, and skin. Afferents from these mechanoreceptors project…”
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Sensory Feedback Control of Locomotor Pattern Generation in Cats and Mice by Akay, Turgay

“…•Locomotion is controlled by a central pattern generator and sensory feedback.•Mice have become a critical animal model for neuroscience of…”
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