Search Results - "Akatov, V S"

Hydroxyapatite for Filling Bone Tissue Defects by Teleshev, A. T., Gorshenev, V. N., Yakovleva, M. A., Fomichev, V. A., Fadeev, R. S., Minaychev, V. V., Akatov, V. S.

“…Hydroxyapatite was synthesized in conditions of mechanoacoustic treatment of an aqueous reaction mixture consisting of ammonium hydrogen phosphate and calcium…”
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Changes in Histone Code Regulation during the Initiation of Paraptosis-Like Death of HEp-2 Tumor Cells by Oxidized Disulfiram Derivatives by Solovieva, M. E., Shatalin, Yu. V., Akatov, V. S.

“…— Disulfiram (DSF) and its oxidized derivatives (DSFoxy) are currently being investigated as potential anticancer agents. We previously found that DSFoxy…”
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The Redox-Catalytic Properties of Cobalamins by Shatalin, Yu. V., Shubina, V. S., Solovieva, M. E., Akatov, V. S.

“…—Vitamin B12, or cobalamin, is essential for normal body function and is used in the therapies of different diseases. Vitamin B12 has anti-inflammatory and…”
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Studying Signaling Pathway Activation in TRAIL-Resistant Macrophage-Like Acute Myeloid Leukemia Cells by Lomovskaya, Y V, Krasnov, K S, Kobyakova, M I, Kolotova, A A, Ermakov, A M, Senotov, A S, Fadeeva, I S, Fetisova, E I, Lomovsky, A I, Zvyagina, A I, Akatov, V S, Fadeev, R S

“…Acute myeloid leukemia (AML) is a malignant neoplasm characterized by extremely low curability and survival. The inflammatory microenvironment and maturation…”
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Myeloid Differentiation Increases Resistance of Leukemic Cells to TRAIL-Induced Death by Reducing the Expression of DR4 and DR5 Receptors by Lomovskaya, Ya. V., Kobyakova, M. I., Senotov, A. S., Fadeeva, I. S., Lomovsky, A. I., Krasnov, K. S., Shtatnova, D. Yu, Akatov, V. S., Fadeev, R. S.

“…The study of the mechanisms of resistance of tumor cells to TRAIL-induced death remains an urgent task since this cytokine is an important highly selective…”
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Reversible Increase in Resistance of A-431 Carcinoma Cells to TRAIL-Induced Apoptosis in Confluent Cultures Corresponds to a Decrease in Expression of DR4 and DR5 Receptors by Fadeev, R. S., Dolgikh, N. V., Chekanov, A. V., Senotov, A. S., Krasnov, K. S., Kobyakova, M. I., Lomovskaya, Ya. V., Fadeeva, I. S., Akatov, V. S.

“…— TRAIL (TNF alpha Related Apoptosis Inducing Ligand) cytokine is of great interest for the development of targeted antitumor drugs. We have previously found a…”
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Hydroxycobalamin catalyzes the oxidation of diethyldithiocarbamate and increases its cytotoxicity independently of copper ions by Solovieva, M E, Shatalin, Yu V, Solovyev, V V, Sazonov, A V, Kutyshenko, V P, Akatov, V S

“…It is known that some metals (Cu, Zn, Cd, Au) markedly increase the toxic effect of thiocarbamates. It was shown in the present study that hydroxycobalamin (a…”
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Effect of Morphogenetic Protein BMP-2 on X-Ray Density of Bone Defect in the Experiment by Yarygin, N. V., Parshikov, M. V., Prosvirin, A. A., Gur’ev, V. V., Govorov, M. V., Bosykh, V. G., Akatov, V. S., Chekanov, A. V.

“…In experiments on Wistar rats, a simulated defect in the flat bones of the skull was filled with a collagen sponge of animal origin impregnated with BMP-2 or…”
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Appearance of Signs of Differentiation and Pro-inflammatory Phenotype in Acute Myeloid Leukemia Cells THP-1 with an Increase in Their TRAIL Resistance in Cell Aggregates in Vitro by Kobyakova, M. I., Evstratova, Ya. V., Senotov, A. S., Lomovsky, A. I., Minaichev, V. V., Zvyagina, A. I., Solovieva, M. E., Fadeeva, I. S., Akatov, V. S., Fadeev, R. S.

“…Previously, we found a significant increase in TRAIL (TNFα-related apoptosis-inducing ligand) resistance of acute myeloid leukemia (AML) cells in multicellular…”
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Melatonin Enhances the Chemotherapeutic Effect of Cytarabin in HL-60 Cells by Lomovsky, A. I., Baburina, Yu. L., Kobyakova, M. I., Fadeev, R. S., Akatov, V. S., Krestinina, O. V.

“…The combined effect of melatonin and cytarabin at low concentration on the cells of acute promyelocytic leukemia HL-60 was studied. It has been shown that the…”
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Difference in Activation of Signaling Pathways in A431 Cells with Confluence-Dependent and Confluence-Independent TRAIL Resistance by Dolgikh, N. V., Chekanov, A. V., Fadeev, R. S., Akatov, V. S.

“…The mechanisms underlying cancer cell resistance to TRAIL-induced apoptosis are highly diverse and are of scientific and practical interest. We have…”
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Study of Biointegration and Elastic-Strength Properties of a New Xenopericardium-Based Biomaterial for Reconstructive Cardiovascular Surgery by Fadeeva, I. S., Sorkomov, M. N., Zvyagina, A. I., Britikov, D. V., Sachkov, A. S., Evstratova, Ya. V., Fadeev, R. S, Muratov, R. M., Akatov, V. S.

“…We analyzed biocompatibility, elastic-strength properties, and biointegration potential of a new biomaterial made of xenopericardium for reconstructive…”
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mechanism of cytotoxic action of acetylcysteine in combination with vitamin B₁₂b by Faskhutdinova, A. A, Akatov, V. S, Solov'eva, M. E, Solov'ev, V. S, Chailakhyan, L. M

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Implants for Reconstructive Surgery Based on Electrospun Poly(3-hydroxybutyrate) Fibers by Ol’khov, A. A., Akatov, V. S., Prosvirin, A. A., Staroverova, O. V., Filatov, Yu. N., Gol’dshtrakh, M. A., Iordanskii, A. L.

“…Nonwoven microfibrous materials based on poly(3-hydroxybutyrate) (PHB) were produced by electrospinning. The fiber supramolecular structure was investigated…”
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Inhibition of NF-kB Activation Decreases Resistance in Acute Myeloid Leukemia Cells to TRAIL-induced Apoptosis in Multicellular Aggregates by Fadeev, R S, Solovieva, M E, Slyadovskiy, D A, Zakharov, S G, Fadeeva, I S, Senotov, A S, Golenkov, A K, Akatov, V S

“…Suppression of resistance in acute myeloid leukemia cells to TRAIL-induced apoptosis in multicellular aggregates, was studied using small molecule inhibitors…”
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Thiol Antioxidants in Combination with Vitamin B12 Induce Apoptotic Death of Human Lymphocytic Leukemia Cells by Destabilization of Lysosomes with the Involvement of Iron Ions by Solovyeva, M. E., Faskhutdinova, A. A., Solovyev, V. V., Akatov, V. S.

“…The extensively used thiol antioxidants (dithiothreitol, glutathione, and N-acetylcysteine) in combination with hydroxycobalamine (vitamin B 12 ) gain toxic…”
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Apoptotic death of human lympholeukemia HL-60 cells resultant from combined effect of cobalt octa-4,5-carboxyphthalocyanine propylenglycol ether and ascorbate by Akatov, V S, Medvedev, A I, Solov'eva, M E, Merkushina, A I, Leshchenko, V V

“…Cobalt octa-4,5-carboxyphthalocyanine propylenglycol ether proposed for antitumor therapy potentiates the cytotoxic effect of ascorbate on HL-60 human leukemia…”
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Multikinase inhibitor sorafenib and HDAC inhibitor suberoylanilide hydroxamic acid suppress confluent resistance of cancer cells to recombinant protein izTRAIL by Fadeev, R S, Chekanov, A V, Dolgikh, N V, Akatov, V S

“…Suppression of human tumor cell resistance to TRAIL-induced apoptosis in confluent cultures, using molecular target drugs (sorafenib and SAHA) at non-toxic…”
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INCREASE OF DRUG RESISTANCE OF ACUTE MYELOID LEUKEMIA CELLS IN MULTICELLULAR AGGREGATES IN VITRO by Zakharov, S. G., Golenkov, A. K., Mitina, T. A., Lutskaya, T. D., Belousov, K. A., Fadeev, R. S., Solovieva, M. E., Senotov, A. S., Akatov, V. S.

“…Background: Therapeutic efficiency in treatment of acute myeloid leukemia (AML) ranges from 20 to 45%. One of the causes of the latter is a drug resistance…”
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Resistance of cancer cells to the TRAIL-induced apoptosis in confluent cultures by Fadeev, R. S., Chekanov, A. V., Dolgikh, N. V., Akatov, V. S.

“…TRAIL (TNF-alpha Related Apoptosis-Inducing Ligand) is an attractive candidate for anticancer therapy. TRAIL selectively kills tumor cells, without damaging…”
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