Search Results - "Akaiwa, Mina"
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Cloning and Characterization of the Hakata Antigen, a Member of the Ficolin/Opsonin p35 Lectin Family
Published in The Journal of biological chemistry (14-08-1998)“…The Hakata antigen is a novel, thermolabile β2-macroglycoprotein that reacts with sera from patients suffering from systemic lupus erythematosus. In this study…”
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Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor α chain 1: redundancy of requirement of tyrosine residue for STAT3 activation
Published in International immunology (01-11-2000)“…IL-4 and IL-13 are pleiotropic cytokines whose biological activities overlap with each other. IL-13 receptor α chain 1 (IL-13Rα1) is necessary for binding to…”
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Identification of an alternative splicing variant of cathepsin C/dipeptidyl-peptidase I
Published in Gene (26-06-2002)“…Cathepsin C/dipeptidyl-peptidase I is a papain-like lysosomal cysteine proteinase implicated in the processing of various proenzymes to their active forms. In…”
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Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma
Published in Journal of allergy and clinical immunology (01-06-2002)“…Background: A substantial body of evidence exists to support the pivotal role of IL-13 in the pathogenesis of bronchial asthma. We recently found that a…”
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Hakata Antigen, a New Member of the Ficolin/Opsonin p35 Family, Is a Novel Human Lectin Secreted into Bronchus/Alveolus and Bile
Published in The journal of histochemistry and cytochemistry (01-06-1999)“…Hakata antigen was first reported as a serum protein that reacted with an autoantibody from patients with systemic lupus erythematosus. Recently, it has been…”
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LOCALIZATION OF HUMAN INTERLEUKIN 13 RECEPTOR IN NON-HAEMATOPOIETIC CELLS
Published in Cytokine (Philadelphia, Pa.) (21-01-2001)“…Although the functional roles of interleukin (IL-)13 in haematopoietic cells are well investigated, those in non-haematopoietic cells remain to be addressed…”
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ANALYSIS OF NOVEL DISEASE-RELATED GENES IN BRONCHIAL ASTHMA
Published in Cytokine (Philadelphia, Pa.) (21-09-2002)“…Bronchial asthma is a complex disease characterized by airway inflammation involving interleukin (IL)-4 and IL-13. We have applied microarray analyses to human…”
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Augmentation of Signal Transducer and Activation of Transcription (STAT)6 and STAT3 Expression in Stimulated B and T Cells
Published in Biochemical and biophysical research communications (22-10-2000)“…Signal transducer and activation of transcription (STAT)6 has a central role in the signal transduction of interleukin (IL)-4 and IL-13. It has recently been…”
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Recent advances in understanding how interleukin 13 signals are involved in the pathogenesis of bronchial asthma
Published in Archivum Immunologiae et Therapiae Experimentalis (2000)“…The prevalence of allergic disease has dramatically increased in recent decades, especially in urban and industrialized areas. Allergic diseases are disorders…”
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