Search Results - "Akahoho, Eugene"

First-in-Human Phase 1 Trial of Agarose Beads Containing Murine RENCA Cells in Advanced Solid Tumors by Smith, Barry H., Parikh, Tapan, Andrada, Zoe P., Fahey, Thomas J., Berman, Nathaniel, wiles, Madeline, Nazarian, Angelica, Thomas, Joanne, Arreglado, Anna, Akahoho, Eugene, wolf, David J., Levine, Daniel M., Parker, Thomas S., Gazda, Lawrence S., Ocean, Allyson J.

“…PURPOSE: Agarose macrobeads containing mouse renal adenocarcinoma cells (RMBs) release factors, suppressing the growth of cancer cells and prolonging survival…”
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Possible role of the systemic inflammatory reaction in defining tumor responder vs. nonresponder in cancer macrobead therapy by Smith, Barry H., Andrada, Zoe Padua, Nazarian, Angelica, Ocean, Allyson J., Parikh, Tapan, Lu, Jia, Arreglado, Anna, Fahey, Thomas J., Berman, Nathaniel, Gazda, Larry, Martis, Prithy, Laramore, Melissa, Akahoho, Eugene, Thomas, Joanne, Wolf, David J.

“…Abstract only 572 Background: Peritoneal implantation of mouse renal adenocarcinoma cell-containing (RENCA) Macrobead (MB) represents a cell-system-based…”
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Abstract CT216: Phase I/IIa non-randomized open-label trials with mouse renal adenocarcinoma (RENCA) cell containing agarose-agarose macrobeads in patients with treatment-resistant metastatic colorectal carcinoma by Ocean, Allyson J., Berman, Nathaniel, Parikh, Tapan, Andrada, Zoe P., Nazarian, Angelica, Thomas, Joanne, Akahoho, Eugene, Stoms, George, Yaroshinsky, Alex, Fahey, Thomas J., Wolf, David J., Gazda, Lawrence S., Smith, Barry H.

“…Abstract Background: The purpose of phase I/IIa trials of RENCA tumor cells encapsulated in two concentric agarose layers is to evaluate safety and efficacy of…”
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Abstract 2486: Docetaxel resistant cells display cancer stem cell properties and regulate growth via PI3/Akt signaling by Martis, Prithy C., Laramore, Melissa A., Gazda, Hunter L., Dudley, Atira, Dumpala, Pradeep R., Ocean, Allyson J., Berman, Nathaniel, Parikh, Tapan, Andrada, Zoe P., Nazarian, Angelica, Thomas, Joanne, Akahoho, Eugene, Stoms, George, Yaroshinsky, Alex, Fahey, Thomas J., Wolf, David J., Gazda, Lawrence S., Smith, Barry H.

“…Abstract Both normal organogenesis and tumor development follow a Gompertzian growth curve. An understanding of the mechanisms operating in these apparently…”
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Phase I/II trial of intraperitoneal implantation of agarose-agarose macrobeads (MB) containing mouse renal adenocarcinoma cells (RENCA) in patients (pts) with advanced colorectal cancer (CRC) by Ocean, Allyson J., Parikh, Tapan, Berman, Nathaniel, Escalon, Juliet, Shah, Manish A., Andrada, Zoe, Akahoho, Eugene, Pogoda, Janice M., Stoms, George B., Escobia, Verula B, Ruggiero, Joseph T., Fahey, Thomas J., Smith, Barry H.

“…Abstract only e14517 Background: RENCA tumor cells encapsulated in two concentric agarose layers which release signals to treat advanced cancers is a novel…”
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Phase 1 study of intravenous rigosertib (ON 01910.Na), a novel benzyl styryl sulfone structure producing G2/M arrest and apoptosis, in adult patients with advanced cancer by Ohnuma, Takao, Lehrer, Deborah, Ren, Chen, Cho, Sool Yeon, Maniar, Manoj, Silverman, Lewis, Sung, Max, Gretz, 3rd, Herbert F, Benisovich, Vladimir, Navada, Shyamala, Akahoho, Eugene, Wilck, Eric, Taft, David R, Roboz, John, Wilhelm, Francois, Holland, James F

“…Rigosertib (ON 01910.Na), a synthetic novel benzyl styryl sulfone, was administered to 28 patients with advanced cancer in a Phase I trial in order to…”
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