Search Results - "Akagi, Kazutaka"

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  1. 1

    Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila by Sharma, Amit, Akagi, Kazutaka, Pattavina, Blaine, Wilson, Kenneth A., Nelson, Christopher, Watson, Mark, Maksoud, Elie, Harata, Ayano, Ortega, Mauricio, Brem, Rachel B., Kapahi, Pankaj

    Published in Scientific reports (05-11-2020)
    “…Exposure to genotoxic stress by environmental agents or treatments, such as radiation therapy, can diminish healthspan and accelerate aging. We have developed…”
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  2. 2

    Proteasome activity determines pupation timing through the degradation speed of timer molecule Blimp‐1 by Aly, Hamdy, Akagi, Kazutaka, Ueda, Hitoshi

    Published in Development, growth & differentiation (01-10-2018)
    “…The transcriptional repressor Blimp‐1 is a labile protein. This characteristic is key for determining pupation timing because the timing of the disappearance…”
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  3. 3

    Dietary restriction improves intestinal cellular fitness to enhance gut barrier function and lifespan in D. melanogaster by Akagi, Kazutaka, Wilson, Kenneth A, Katewa, Subhash D, Ortega, Mauricio, Simons, Jesse, Hilsabeck, Tyler A, Kapuria, Subir, Sharma, Amit, Jasper, Heinrich, Kapahi, Pankaj

    Published in PLoS genetics (01-11-2018)
    “…Loss of gut integrity is linked to various human diseases including inflammatory bowel disease. However, the mechanisms that lead to loss of barrier function…”
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    New Possibilities for Evaluating the Development of Age-Related Pathologies Using the Dynamical Network Biomarkers Theory by Akagi, Kazutaka, Koizumi, Keiichi, Kadowaki, Makoto, Kitajima, Isao, Saito, Shigeru

    Published in Cells (Basel, Switzerland) (01-09-2023)
    “…Aging is the slowest process in a living organism. During this process, mortality rate increases exponentially due to the accumulation of damage at the…”
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  6. 6

    The binding of multiple nuclear receptors to a single regulatory region is important for the proper expression of EDG84A in Drosophila melanogaster by Akagi, Kazutaka, Kageyama, Yuji, Kayashima, Yasunari, Takakura, Yusuke, Hirose, Susumu, Ueda, Hitoshi

    Published in Journal of molecular biology (09-01-2013)
    “…Nuclear receptor transcription factor family members share target sequence similarity; however, little is known about how these factors exert their specific…”
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  7. 7

    Drosophila Blimp-1 Is a Transient Transcriptional Repressor That Controls Timing of the Ecdysone-Induced Developmental Pathway by Agawa, Yasuo, Sarhan, Moustafa, Kageyama, Yuji, Akagi, Kazutaka, Takai, Masayoshi, Hashiyama, Kazuya, Wada, Tadashi, Handa, Hiroshi, Iwamatsu, Akihiro, Hirose, Susumu, Ueda, Hitoshi

    Published in Molecular and Cellular Biology (01-12-2007)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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  8. 8

    2B-02 Control mechanism of prepupal period in different Drosophila species by AKAGI Kazutaka, SARHAN Moustafa, UEDA Hitoshi

    Published in Genes & Genetic Systems (2010)
    “…Living organisms somehow determine developmental timing in their life. Intriguingly, in Drosophila melanogaster, the prepupal period is 12 hours at standard…”
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  9. 9

    General sessions1B-08 Transcriptional repressor Blimp-1 works as an hourglass in the biological timer system to determine pupation timing in Drosophila by AKAGI Kazutaka, SARHAN Moustafa, UEDA Hitoshi

    Published in Genes & Genetic Systems (2009)
    “…At the onset of metamorphosis in D.melanogaster, a large pulse of ecdysone causes puparium formation and this is followed by another small ecdysone pulse that…”
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  10. 10

    2C-09 Determination mechanism of pupation timing by unstable transcription factor Blimp-1 in Drosophila by AKAGI Kazutaka, SARHAN Moustafa, UEDA Hitoshi

    Published in Genes & Genetic Systems (2007)
    “…We have recently found that Blimp-1, which induced directly by ecdysone plays important roles in determining the precise timing of FTZ-F1 expression and the…”
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    Regulatory mechanisms of ecdysone‐inducible Blimp‐1 encoding a transcriptional repressor that is important for the prepupal development in Drosophila by Akagi, Kazutaka, Ueda, Hitoshi

    Published in Development, growth & differentiation (01-06-2011)
    “…Blimp‐1 is an ecdysone‐inducible transcription factor that is expressed in the early stage of the prepupal period. The timing of its disappearance determines…”
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  14. 14

    A biological timer in the fat body comprising Blimp-1, βFtz-f1 and Shade regulates pupation timing in Drosophila melanogaster by Akagi, Kazutaka, Sarhan, Moustafa, Sultan, Abdel-Rahman S, Nishida, Haruka, Koie, Azusa, Nakayama, Takumi, Ueda, Hitoshi

    Published in Development (Cambridge) (01-07-2016)
    “…During the development of multicellular organisms, many events occur with precise timing. In Drosophila melanogaster, pupation occurs about 12 h after puparium…”
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  15. 15

    A biological timer in the fat body comprised of Blimp-1, βFTZ-F1 and Shade regulates pupation timing in Drosophila melanogaster by Akagi, Kazutaka, Sarhan, Moustafa, Sultan, Abdel-Rahman, Nishida, Haruka, Koie, Azusa, Nakayama, Takumi, Ueda, Hitoshi

    Published in Development (Cambridge) (01-01-2016)
    “…During the development of multicellular organisms, many events occur with precise timing. In Drosophila melanogaster, pupation occurs about 12 hours after…”
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    Journal Article
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    The Binding of Multiple Nuclear Receptors to a Single Regulatory Region Is Important for the Proper Expression of EDG84A in Drosophilamelanogaster by Akagi, Kazutaka, Kageyama, Yuji, Kayashima, Yasunari, Takakura, Yusuke, Hirose, Susumu, Ueda, Hitoshi

    Published in Journal of molecular biology (09-01-2013)
    “…Nuclear receptor transcription factor family members share target sequence similarity; however, little is known about how these factors exert their specific…”
    Get full text
    Journal Article