Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population

Metabolic syndrome (MS) amplifies hypertension (HTN) associated with increased risk of cardiovascular disease (CVD). MS components and other CVD risk measures were investigated in different stages of hypertension. 534 apparently healthy Nigerian traders aged 18–105 years were participants of a cohor...

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Bibliographic Details
Published in:	International Journal of Hypertension Vol. 2013; no. 2013; pp. 145 - 150
Main Authors:	Ojo Owolabi, Mayowa, Oyewole, O. E., Olaniyi, J. A., Fasanmade, A. A., Charles-Davies, M. A., Adebusuyi, J. R., Hassan, O., Ajobo, M. T., Ebesunun, M. O., Adigun, K., Akinlade, K. S., Fabian, U. A., Popoola, O. O., Rahamon, S. K., Okunbolade, W., Ogunlakin, M. A., Arinola, O. G., Agbedana, E. O
Format:	Journal Article
Language:	English
Published:	Cairo, Egypt Hindawi Limiteds 01-01-2013 Hindawi Puplishing Corporation Hindawi Publishing Corporation John Wiley & Sons, Inc Hindawi Limited
Subjects:	Cholesterol Complications and side effects Hypertension Influence Metabolic syndrome X Risk factors Nigeria
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Summary:	Metabolic syndrome (MS) amplifies hypertension (HTN) associated with increased risk of cardiovascular disease (CVD). MS components and other CVD risk measures were investigated in different stages of hypertension. 534 apparently healthy Nigerian traders aged 18–105 years were participants of a cohort study. The International Diabetes Federation (2005) and the National High Blood Pressure Education Program Coordinating Committee criteria were used for MS and HTN classifications, respectively. Anthropometric indices were obtained by standard methods. Levels of fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), and high-density lipoprotein cholesterol (HDLC) were determined by enzymatic methods, while low-density lipoprotein cholesterol (LDLC) was calculated. Data analysed statistically were significant at P<0.05. 143 (26.8%), 197 (36.9%), and 194 (36.3%) of the traders had normotension, pre-HTN and HTN (stages 1 and 2), respectively. All indices tested except HDLC were significantly different among BP groups (P<0.05). Waist to hip (WHR) and waist to height (WHT) ratios were significantly different between HTN groups (P<0.05). HTN was associated with MS and female gender (P<0.05). Metabolic alterations and significant HTN were observed. Treatment of the individual components of the syndrome and improvement of modifiable metabolic factors may be necessary to reduce MS and high BP.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Academic Editor: Mandy Kwan
ISSN:	2090-0392 2090-0384 2090-0392
DOI:	10.1155/2013/351357