Search Results - "Ajimi, Syozo"

Combined repeated dose and reproductive/developmental toxicity screening test of tert-butylhydrazine monohydrochloride in rats by Kobayashi, Toshio, Aso, Sunao, Koga, Takayuki, Hoshuyama, Satsuki, Oshima, Yutaka, Miyata, Katsumi, Kusune, Yuji, Muroi, Takako, Yoshida, Tomohiko, Hasegawa, Ryuichi, Ajimi, Syozo, Furukawa, Kotaro

“…tert-Butylhydrazine monohydrochloride was daily administered by gavage to groups of Crl:CD (SD)IGS rats at doses of 0 (control), 0.8, 4, or 20 mg/kg/day…”
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Application of the Improved BALB/c 3T3 Cell Transformation Assay to the Examination of the Initiating and Promoting Activities of Chemicals: The Second Inter-laboratory Collaborative Study by the Non-genotoxic Carcinogen Study Group of Japan by Tsuchiya, Toshiyuki, Umeda, Makoto, Tanaka, Noriho, Sakai, Ayako, Nishiyama, Hiroshi, Yoshimura, Isao, Ajimi, Syozo, Asada, Shin, Asakura, Masumi, Baba, Hiroshi, Dewa, Yasuaki, Ebe, Youji, Fushiwaki, Yuichi, Hagiwara, Yuji, Hamada, Shuichi, Hamamura, Tetsuo, Iwase, Yumiko, Kajiwara, Yoshitsugu, Kasahara, Yasushi, Kato, Yukihiko, Kawabata, Masayoshi, Kitada, Emiko, Kaneko, Kazuko, Kizaki, Yuko, Kubo, Kinya, Miura, Daisaku, Mashiko, Kaori, Mizuhashi, Fukutaro, Muramatsu, Dai, Nakajima, Madoka, Nakamura, Tetsu, Oishi, Hidetoshi, Sasaki, Toshiaki, Shimada, Sawako, Takahashi, Chitose, Takeda, Yuko, Wakuri, Sinobu, Yajima, Nobuhiro, Yajima, Satoshi, Yatsushiro, Tomoko

“…The Non-genotoxic Carcinogen Study Group in the Environmental Mutagen Society of Japan organised the second step of the inter-laboratory collaborative study on…”
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A subchronic (180-day) oral toxicity study of ethyl tertiary-butyl ether, a bioethanol, in rats by Miyata, Katsumi, Koga, Takayuki, Aso, Sunao, Hoshuyama, Satsuki, Ajimi, Syozo, Furukawa, Kotaro

“…Abstract A subchronic (180-day) toxicity study was conducted to evaluate the effects of ethyl tertiary-butyl ether (ETBE), a biomass fuel, in male and female…”
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Verification of the BALB/c 3T3 cell transformation assay after improvement by using an ITES-medium by Kajiwara, Yoshitsugu, Ajimi, Syozo

“…We carried out the first-step verification study on our ITES-medium-improved BALB/c 3T3 cell transformation assay. In order to estimate its potential use as a…”
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Application of the Improved BALB/c 3T3 Cell Transformation Assay to the Examination of the Initiating and Promoting Activities of Chemicals: The Second Interlaboratory Collaborative Study by the Non-genotoxic Carcinogen Study Group of Japan by Tsuchiya, Toshiyuki, Umeda, Makoto, Tanaka, Noriho, Sakai, Ayako, Nishiyama, Hiroshi, Yoshimura, Isao, Ajimi, Syozo, Asada, Shin, Asakura, Masumi, Baba, Hiroshi, Dewa, Yasuaki, Ebe, Youji, Fushiwaki, Yuichi, Hagiwara, Yuji, Hamada, Shuichi, Hamamura, Tetsuo

“…The Non-genotoxic Carcinogen Study Group in the Environmental Mutagen Society of Japan organised the second step of the inter-laboratory collaborative study on…”
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新規頻尿・尿失禁治療剤 (±)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydtoxy-2-phenylacetate monohydrochloride monohydrate (NS-21) の変異原性試験 by 大塚, 雅則, 梶原, 美次, 安心院, 祥三, 島崎, 博子, 菊野, 秩, 小椋, 正造, 稲井, 恒彦, 柿本, 敬次郎, 田村, 博信, 渡辺, 正孝, 鷲見, 信好

“…NS-21の細菌を用いる復帰突然変異試験, 哺乳類培養細胞を用いる染色体異常試験およびマウスを用いる小核試験を実施し, 以下の成績を得た。細菌を用いる復帰突然変異試験では, サルモネラ菌のTA100, TA1535, TA98およびTA1537ならびに大腸菌のWP2uvrAを用いて,…”
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Improvement of carcinogen detection in the BALB/3T3 cell transformation assay by using a rich basal medium supplemented with low concentration of serum and some growth factors by Kajiwara, Yoshitsugu, Ajimi, Syozo, Hosokawa, Asami, Maekawa, Kazuyuki

“…To improve the detection sensitivity and reproducibility of the transformation assay using BALB/3T3 cells, we scrutinized a new assay method in which the cells…”
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MUTAGENICITY STUDIES OF (±)-4-DIETHYLAMINO-1, 1, -DIMETHYLBUT-2-YN-1-YL 2-CYCLHOEXYL-2-HYDROXY-2-PHENYLACETATE MONOHYDROCHLORIDE MONOHYDRATE (NS-21), A NOVEL DRUG FOR URINARY FREQUENCY AND INCONTINENCE by OTSUKA, Masanori, KAJIWARA, Yoshitsugu, AJIMI, Syozo, SHIMAZAKI, Hiroko, KIKUNO, Tsukasa, OGURA, Syozo, INAI, Tsunehiko, KAKIMOTO, Keijiro, TAMURA, Hironobu, WATANABE, Masataka, SUMI, Nobuyoshi

“…The mutagenicity of (±)-4-diethylamino-1, 1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a new drug for…”
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Mutagenicity studies of (±)-4-diethylamino-1,1,-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence by OTSUKA, M, KAJIWARA, Y, SUMI, N, AJIMI, S, SHIMAZAKI, H, KIKUNO, T, OGURA, S, INAI, T, KAKIMOTO, K, TAMURA, H, WATANABE, M

“…The mutagenicity of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a new drug for…”
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