Search Results - "Ajdzanovic Vladimir"
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Citrus Flavanones Upregulate Thyrotroph Sirt1 and Differently Affect Thyroid Nrf2 Expressions in Old-Aged Wistar Rats
Published in Journal of agricultural and food chemistry (05-08-2020)“…A growing population of elderly people consume citrus flavanones, naringenin, and hesperetin in the form of fruits or juices. Flavanones are bioactives with…”
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2
Citrus flavanones naringenin and hesperetin improve antioxidant status and membrane lipid compositions in the liver of old-aged Wistar rats
Published in Experimental gerontology (01-11-2016)“…This study aimed to investigate effects of citrus flavanones naringenin (NAR) and hesperetin (HES) on liver antioxidant status and membrane phospholipid…”
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3
Genistein regulates calcium and phosphate homeostasis without activation of MEK 1/2 signalling pathway in an animal model of the andropause
Published in Annals of anatomy (01-01-2022)“…Soy isoflavone genistein interplays with numerous physiological or pathophysiological processes during ageing. However, its protective role and underlying…”
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4
Genistein and daidzein treatments differently affect uterine homeostasis in the ovary-intact middle-aged rats
Published in Toxicology and applied pharmacology (15-01-2018)“…This study aimed to investigate the effects of soy isoflavones, genistein (GEN) and daidzein, (DAI) on the uterine function in ovary-intact middle-aged rats…”
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Effects of soy phytoestrogens on pituitary-ovarian function in middle-aged female rats
Published in Endocrine (01-12-2015)“…The aim of this study was to assess the effects of genistein (G) and daidzein (D) on the histological, hormonal, and functional parameters of the…”
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The phytoestrogen genistein prevents trabecular bone loss and affects thyroid follicular cells in a male rat model of osteoporosis
Published in Journal of anatomy (01-08-2018)“…As a major phytoestrogen of soy, genistein effectively prevents bone loss in both humans and rat models of osteoporosis. However, although the bone‐sparing…”
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7
Adverse effect of dexamethasone on development of the fetal rat ovary
Published in Fundamental & clinical pharmacology (01-04-2019)“…Dexamethasone (Dx) is often used in obstetric practice to promote fetal lung maturation and to prevent respiratory distress syndrome when the risk of preterm…”
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The adrenal cortex after estradiol or daidzein application in a rat model of the andropause: Structural and hormonal study
Published in Annals of anatomy (01-07-2020)“…Daidzein application may represent an effective and less harmful alternative to indicated, classical estrogenization of ageing men. The aim of this study was…”
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Soy isoflavone effects on the adrenal glands of orchidectomized adult male rats: a comprehensive histological and hormonal study
Published in Histology and histopathology (01-08-2018)“…Genistein (G) and related soy phytoestrogens have been studied for potential usefulness in different chronic diseases, and may ameliorate signs of aging. They…”
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Vitamin D 3 Treatment Alters Thyroid Functional Morphology in Orchidectomized Rat Model of Osteoporosis
Published in International journal of molecular sciences (12-01-2022)“…Vitamin D plays an essential role in prevention and treatment of osteoporosis. Thyroid hormones, in addition to vitamin D, significantly contribute to…”
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Effects of age and soybean isoflavones on hepatic cholesterol metabolism and thyroid hormone availability in acyclic female rats
Published in Experimental gerontology (01-06-2017)“…Soy-food and its isoflavones, genistein (G) and daidzein (D), were reported to exert mild cholesterol-lowering effect, but the underlying mechanism is still…”
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12
Prenatal dexamethasone exposure and developmental programming of the ovary of the offspring: a structural study in the rat
Published in Reproduction fertility and development (01-02-2021)“…Overexposure to glucocorticoids during fetal development alters fetal organ growth and maturation patterns, which can result in adverse programming outcomes in…”
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Citrus flavanones mildly interfere with pituitary-thyroid axis in old-aged male rats
Published in Acta histochemica (01-04-2017)“…•NAR and HES decreased relative colloid volume and increased relative volume of stroma.•No signs of thyroid hypertrophy or absolute volume change were…”
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Daidzein upregulates anti-aging protein Klotho and NaPi 2a cotransporter in a rat model of the andropause
Published in Annals of anatomy (01-01-2019)“…In a rat model of the andropause we aimed to examine the influence of daidzein, soy isoflavone, on the structure and function of parathyroid glands (PTG) and…”
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15
Response of trabecular bone, thyroid C and follicular cells to synthetic salmon calcitonin in middle‐aged orchidectomized male rats
Published in Journal of anatomy (01-06-2017)“…In contrast to studies in women, male osteoporosis is poorly understood and strictly related to advancing age. Among the first antiresorptive substances used…”
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Testosterone application decreases the capacity for ACTH and corticosterone secretion in a rat model of the andropause
Published in Acta histochemica (01-07-2015)“…The culminating phase of ageing in males–andropause is characterized by enhanced activity of the hypothalamic–pituitary–adrenal axis and frequent…”
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The effects of prenatal dexamethasone exposure and fructose challenge on pituitary-adrenocortical activity and anxiety-like behavior in female offspring
Published in Tissue & cell (01-02-2020)“…•Fetal dexamethasone exposure increase ACTH level in adult female rat offspring.•Smaller adrenals produced aldosterone and corticosterone at control…”
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Orchidectomy of middle-aged rats decreases liver deiodinase 1 and pituitary deiodinase 2 activity
Published in Journal of endocrinology (01-11-2012)“…Endogenous androgens are involved in regulation of thyroid function and metabolism of thyroid hormones. As serum testosterone level progressively declines with…”
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Membrane Fluidity, Invasiveness and Dynamic Phenotype of Metastatic Prostate Cancer Cells after Treatment with Soy Isoflavones
Published in The Journal of membrane biology (01-04-2013)“…Soy isoflavones represent hopeful unconventional remedies in the therapy of prostate cancer. The aim of our study was to determine the effects of genistein and…”
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Tamoxifen stimulates calcitonin‐producing thyroid C‐cells and prevents trabecular bone loss in a rat model of androgen deficiency
Published in Journal of anatomy (01-05-2015)“…Thyroid C‐cells produce calcitonin (CT), a hypocalcemic hormone, that acts as an inhibitor of bone resorption. In this study, we investigated the effects of…”
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