Search Results - "Ajay Kumar, R."

The Error-Prone Polymerase DnaE2 Mediates the Evolution of Antibiotic Resistance in Persister Mycobacterial Cells by Salini, S, Bhat, Sinchana G, Naz, Saba, Natesh, Ramanathan, Kumar, R Ajay, Nandicoori, Vinay Kumar, Kurthkoti, Krishna

“…Applying antibiotics to susceptible bacterial cultures generates a minor population of persisters that remain susceptible to antibiotics but can endure them…”
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Acetylation of Isoniazid Is a Novel Mechanism of Isoniazid Resistance in Mycobacterium tuberculosis by Arun, K B, Madhavan, Aravind, Abraham, Billu, Balaji, M, Sivakumar, K C, Nisha, P, Kumar, R Ajay

“…Isoniazid (INH), one of the first-line drugs used for the treatment of tuberculosis, is a prodrug which is activated by the intracellular KatG enzyme of The…”
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Synthesis, antimicrobial, antimycobacterial and structure–activity relationship of substituted pyrazolo-, isoxazolo-, pyrimido- and mercaptopyrimidocyclohepta[ b]indoles by Yamuna, Ezhumalai, Kumar, R. Ajay, Zeller, Matthias, Rajendra Prasad, Karnam Jayarampillai

“…A new class of heterocycles, specifically substituted pyrazolo-, isoxazolo- and pyrimidocyclohepta[ b]indoles, has been prepared by condensation of substituted…”
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New 1,3-oxazolo[4,5- c]quinoline derivatives: Synthesis and evaluation of antibacterial and antituberculosis properties by Eswaran, Sumesh, Adhikari, Airody Vasudeva, Ajay Kumar, R.

“…A new class of fused oxazoloquinoline derivatives was synthesized starting from 2-bromo-1-phenylethanones 1a-b through multi-step reactions. The newly…”
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Mycobacterium tuberculosis Infection Induces HDAC1-Mediated Suppression of IL-12B Gene Expression in Macrophages by Chandran, Aneesh, Antony, Cecil, Jose, Leny, Mundayoor, Sathish, Natarajan, Krishnamurthy, Kumar, R Ajay

“…Downregulation of host gene expression is one of the many strategies employed by intracellular pathogens such as Mycobacterium tuberculosis (MTB) to survive…”
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Mn Modified Mesoporous TiO2 Particles: Synthesis, Characterization and Photovoltaic Application by Ajay Kumar, R., Yechuri, Sandeep, Kiran Kumar, G., Rajesh Babu, B., Rajesh, Ch

“…In this work, manganese (Mn) modified mesoporous titanium dioxide (Mn-MT) particles were synthesized by a hydrothermal process using an impregnation method and…”
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Resveratrol – A potential inhibitor of biofilm formation in Vibrio cholerae by Augustine, Nimmy, Goel, A.K., Sivakumar, K.C., Ajay Kumar, R., Thomas, Sabu

“…Resveratrol, a phytochemical commonly found in the skin of grapes and berries, was tested for its biofilm inhibitory activity against Vibrio cholerae. Biofilm…”
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Streptomyces sp metabolite(s) promotes Bax mediated intrinsic apoptosis and autophagy involving inhibition of mTOR pathway in cervical cancer cell lines by Dan, Vipin Mohan, Muralikrishnan, Balaji, Sanawar, Rahul, J. S., Vinodh, Burkul, Bhushan Bapusaheb, Srinivas, Kalanghad Puthankalam, Lekshmi, Asha, Pradeep, N. S., Dastager, Syed G., Santhakumari, B., Santhoshkumar, Thankayyan R., Kumar, R. Ajay, Pillai, Madhavan Radhakrishna

“…In cervical cancer, the association between HPV infection and dysregulation of phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of…”
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Comparative Analysis of Mycobacterial Truncated Hemoglobin Promoters and the groEL2 Promoter in Free-Living and Intracellular Mycobacteria by JOSEPH, Sunil V, MADHAVILATHA, G. K, AJAY KUMAR, R, MUNDAYOOR, Sathish

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Electrochemical studies of mesoporous and copper-modified mesoporous TiO2 -anode material by Ajay Kumar, R., Venkateswara Rao, A., Rajesh, Ch

“… Herein, we developed a method to synthesize highly ordered mesoporous TiO 2 (MT) and copper-modified M- TiO 2 (CMT) with a high surface area by the…”
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Whole-Genome Sequences of Two Clinical Isolates of Mycobacterium tuberculosis from Kerala, South India by MADHAVILATHA, G. K, JOSEPH, Biljo V, PAUL, Laiza K, AJAY KUMAR, R, HARIHARAN, Ramkumar, MUNDAYOOR, Sathish

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Molecular epidemiology of Mycobacterium tuberculosis isolates from Kerala, India using IS6110-RFLP, spoligotyping and MIRU-VNTRs by Joseph, Biljo V, Soman, Smitha, Radhakrishnan, Indulakshmi, Hill, Véronique, Dhanasooraj, D., Ajay Kumar, R., Rastogi, Nalin, Mundayoor, Sathish

“…► High prevalence of zero-copy and single copy IS6110 isolates from Kerala. ► MIRU-VNTR showed better discrimination than IS6110-RFLP and spoligotyping. ►…”
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Vaccine delivery system for tuberculosis based on nano-sized hepatitis B virus core protein particles by Dhanasooraj, Dhananjayan, Kumar, R Ajay, Mundayoor, Sathish

“…Nano-sized hepatitis B virus core virus-like particles (HBc-VLP) are suitable for uptake by antigen-presenting cells. Mycobacterium tuberculosis antigen…”
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Mesoporous TiO2 and copper-modified TiO2 nanoparticles: A case study by Ajay Kumar, R., Vasavi Dutt, V. G., Rajesh, Ch

“… In this paper we report the synthesis of mesoporous titanium dioxide (M-TiO 2 ) nanoparticles (NPs) and copper (Cu)-modified M-TiO 2 NPs by the hydrothermal…”
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Defect profiling in organic semiconductor multilayers by Maheshwari, Priya, Pujari, P.K., Sharma, S.K., Sudarshan, K., Dutta, D., Samanta, S., Singh, A., Aswal, D.K., Ajay Kumar, R., Samajdar, I.

“…[Display omitted] ► Defect depth profile studies are carried out in organic semiconductor (OSC) heterostructures using positron accelerator. ► Defects are seen…”
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Interaction of Papillomavirus E2 Protein with the Brm Chromatin Remodeling Complex Leads to Enhanced Transcriptional Activation by AJAY KUMAR, R, NAIDU, Samisubbu R, XIAOYU WANG, IMBALZANO, Anthony N, ANDROPHY, Elliot J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Metabolic Evaluation in Paediatric Urolithiasis: A 4-Year Open Prospective Study by Gajengi, Ajay Kumar R, Wagaskar, Vinayak Gorakhnath, Tanwar, Harshwardhan V, Mhaske, Sunil, Patwardhan, Sujata K

“…Children with urolithiasis are associated with considerable morbidity and commonly associated with metabolic abnormalities. By treating these abnormalities…”
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B1CTcu5: A frog-derived brevinin-1 peptide with anti-tuberculosis activity by Abraham, Parvin, Jose, Leny, Maliekal, Tessy Thomas, Kumar, R. Ajay, Kumar, K. Santhosh

“…•B1CTcu5 peptide inhibited M. tuberculosis H37Rv at 12.5 μg/mL.•It successfully eliminated intracellular M. tuberculosis.•B1CTcu5 is nontoxic to THP1- derived…”
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Structural basis of RNA folding and recognition in an AMP-RNA aptamer complex by Jiang, Feng, Kumar, R. Ajay, Jones, Roger A, Patel, Dinshaw J

“…The catalytic properties of RNA and its well known role in gene expression and regulation are the consequence of its unique solution structures. Identification…”
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Subunit Protein Vaccine Delivery System for Tuberculosis Based on Hepatitis B Virus Core VLP (HBc-VLP) Particles by Dhanasooraj, Dhananjayan, Kumar, R Ajay, Mundayoor, Sathish

“…Despite the development of modern medicine, tuberculosis (TB), caused by the pathogenic bacterium, Mycobacterium tuberculosis (Mtb), remains one of the…”
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