Search Results - "Ajabnoor, Ghada M."
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The Molecular and Genetic Interactions between Obesity and Breast Cancer Risk
Published in Medicina (Kaunas, Lithuania) (01-07-2023)“…Breast cancer (BC) is considered the leading cause of death among females worldwide. Various risk factors contribute to BC development, such as age, genetics,…”
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Ramadan fasting in Saudi Arabia is associated with altered expression of CLOCK, DUSP and IL-1alpha genes, as well as changes in cardiometabolic risk factors
Published in PloS one (06-04-2017)“…During the fasting month of Ramadan, practicing Saudis develop severe disturbances in sleeping and feeding patterns. Concomitantly, cortisol circadian rhythm…”
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The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults-A cross sectional study
Published in PloS one (23-02-2021)“…Population specific associations between cardiovascular disease with various risk factors including pre-hypertension and hypertension were reported. We aimed…”
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Thymoquinone Enhances Paclitaxel Anti-Breast Cancer Activity via Inhibiting Tumor-Associated Stem Cells Despite Apparent Mathematical Antagonism
Published in Molecules (Basel, Switzerland) (20-01-2020)“…Thymoquinone (TQ) has shown substantial evidence for its anticancer effects. Using human breast cancer cells, we evaluated the chemomodulatory effect of TQ on…”
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5
The influence of antioxidant dietary-derived polyphenolic combination on breast cancer: Molecular study
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Breast cancer remains a leading cause of female mortality worldwide. Therefore, novel complementary treatments have been sought. Recently, there has been a…”
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Health impact of fasting in Saudi Arabia during Ramadan: association with disturbed circadian rhythm and metabolic and sleeping patterns
Published in PloS one (08-05-2014)“…Muslims go through strict Ramadan fasting from dawn till sunset for one month yearly. These practices are associated with disturbed feeding and sleep patterns…”
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Gut Microbiota: A Contributing Factor to Obesity
Published in Frontiers in cellular and infection microbiology (30-08-2016)“…Obesity, a global epidemic of the modern era, is a risk factor for cardiovascular diseases (CVD) and diabetes. The pervasiveness of obesity and overweight in…”
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The Possible Effect of the Long-Term Use of Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) on Hba1c and Lipid Profile in Type 2 Diabetes Mellitus: A Retrospective Study in KAUH, Jeddah, Saudi Arabia
Published in Diseases (01-03-2023)“…(1) Background: Type 2 diabetes (T2DM) is a chronic metabolic disease with serious health complications. T2DM is associated with many chronic illnesses,…”
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Exploring the Validity of Available Markers and Indices in the Diagnosis of Nonalcoholic Fatty Liver Disease (NAFLD) in People with Type 2 Diabetes in Saudi Arabia
Published in Diseases (15-01-2023)“…Nonalcoholic fatty liver disease (NAFLD) is common among Saudi patients with type 2 diabetes (T2DM). However, recommended clinical procedures to detect it are…”
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Expanded Somatic Mutation Spectrum of MED12 Gene in Uterine Leiomyomas of Saudi Arabian Women
Published in Frontiers in genetics (14-12-2018)“…MED12, a subunit of mediator complex genes is known to harbor genetic mutations, (mostly in exon 2), causal to the genesis of uterine leiomyomas among…”
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Effect of Ramadan fasting in Saudi Arabia on serum bone profile and immunoglobulins
Published in Therapeutic advances in endocrinology and metabolism (01-10-2015)“…Background: Each year Muslims fast from dawn to sunset for 1 month (Ramadan). In Saudi Arabia, the sleep–wake cycle during Ramadan is severely disturbed and is…”
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12
Molecular modelling and dynamics of CA2 missense mutations causative to carbonic anhydrase 2 deficiency syndrome
Published in Journal of biomolecular structure & dynamics (21-09-2020)“…Carbonic anhydrase 2 (CA2) enzyme deficiency caused by CA2 gene mutations is an inherited disorder characterized by symptoms like osteopetrosis, renal tubular…”
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Molecular designing, virtual screening and docking study of novel curcumin analogue as mutation (S769L and K846R) selective inhibitor for EGFR
Published in Saudi journal of biological sciences (01-03-2019)“…The somatic mutations in ATP binding cleft of the tyrosine kinase binding domain of EGFR are known to occur in 15–40% of non-small cell lung cancer (NSCLC)…”
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Gender Differences in The Factors associated with Hypertension in Non-Diabetic Saudi Adults—A Cross-Sectional Study
Published in International journal of environmental research and public health (29-10-2021)“…The association between lifestyle practices, obesity and increased BP are under-investigated. We aimed to investigate this association to identify the factors…”
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ABCA1 C69T Gene Polymorphism Association with Dysglycemia in Saudi Prediabetic Adults
Published in Genes (02-12-2022)“…Studies suggest that ATP-binding cassette transporter A1 ( C69T) polymorphism is associated with a decreased incidence of type 2 diabetes mellitus (T2DM) and…”
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IABCA1/I C69T Gene Polymorphism Association with Dysglycemia in Saudi Prediabetic Adults
Published in Genes (01-12-2022)“…Studies suggest that ATP-binding cassette transporter A1 (ABCA1 C69T) polymorphism is associated with a decreased incidence of type 2 diabetes mellitus (T2DM)…”
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Abstract 3876: Thymoquinone induces the expression of clock genes in breast cancer cells
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Thymoquinone is naturally occurring bioactive compound which showed cumulative preclinical evidence of anticancer effects. However, its exact…”
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Abstract 4208: Inhibition of proliferation and induction of apoptosis by a novel phytobiological mixture against breast cancer cell lines
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Breast cancer remains a leading cause of women’s death worldwide with progressive emergence of resistance towards approved chemotherapies. For this…”
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