Search Results - "Ajabnoor, Ghada"
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The Molecular and Genetic Interactions between Obesity and Breast Cancer Risk
Published in Medicina (Kaunas, Lithuania) (01-07-2023)“…Breast cancer (BC) is considered the leading cause of death among females worldwide. Various risk factors contribute to BC development, such as age, genetics,…”
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Ramadan fasting in Saudi Arabia is associated with altered expression of CLOCK, DUSP and IL-1alpha genes, as well as changes in cardiometabolic risk factors
Published in PloS one (06-04-2017)“…During the fasting month of Ramadan, practicing Saudis develop severe disturbances in sleeping and feeding patterns. Concomitantly, cortisol circadian rhythm…”
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3
The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults-A cross sectional study
Published in PloS one (23-02-2021)“…Population specific associations between cardiovascular disease with various risk factors including pre-hypertension and hypertension were reported. We aimed…”
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4
Health impact of fasting in Saudi Arabia during Ramadan: association with disturbed circadian rhythm and metabolic and sleeping patterns
Published in PloS one (08-05-2014)“…Muslims go through strict Ramadan fasting from dawn till sunset for one month yearly. These practices are associated with disturbed feeding and sleep patterns…”
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Thymoquinone synergizes gemcitabine anti-breast cancer activity via modulating its apoptotic and autophagic activities
Published in Scientific reports (03-08-2018)“…The use of anti-cancer adjuvant therapy is rationalized by potentiating the efficacy, and/or protecting from major side effects of chemotherapeutics…”
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Thymoquinone Enhances Paclitaxel Anti-Breast Cancer Activity via Inhibiting Tumor-Associated Stem Cells Despite Apparent Mathematical Antagonism
Published in Molecules (Basel, Switzerland) (20-01-2020)“…Thymoquinone (TQ) has shown substantial evidence for its anticancer effects. Using human breast cancer cells, we evaluated the chemomodulatory effect of TQ on…”
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7
Gut Microbiota: A Contributing Factor to Obesity
Published in Frontiers in cellular and infection microbiology (30-08-2016)“…Obesity, a global epidemic of the modern era, is a risk factor for cardiovascular diseases (CVD) and diabetes. The pervasiveness of obesity and overweight in…”
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8
Molecular modelling and dynamics of CA2 missense mutations causative to carbonic anhydrase 2 deficiency syndrome
Published in Journal of biomolecular structure & dynamics (21-09-2020)“…Carbonic anhydrase 2 (CA2) enzyme deficiency caused by CA2 gene mutations is an inherited disorder characterized by symptoms like osteopetrosis, renal tubular…”
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The Possible Effect of the Long-Term Use of Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) on Hba1c and Lipid Profile in Type 2 Diabetes Mellitus: A Retrospective Study in KAUH, Jeddah, Saudi Arabia
Published in Diseases (01-03-2023)“…(1) Background: Type 2 diabetes (T2DM) is a chronic metabolic disease with serious health complications. T2DM is associated with many chronic illnesses,…”
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10
The influence of antioxidant dietary-derived polyphenolic combination on breast cancer: Molecular study
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Breast cancer remains a leading cause of female mortality worldwide. Therefore, novel complementary treatments have been sought. Recently, there has been a…”
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11
Expanded Somatic Mutation Spectrum of MED12 Gene in Uterine Leiomyomas of Saudi Arabian Women
Published in Frontiers in genetics (14-12-2018)“…MED12, a subunit of mediator complex genes is known to harbor genetic mutations, (mostly in exon 2), causal to the genesis of uterine leiomyomas among…”
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12
ABCA1 C69T Gene Polymorphism Association with Dysglycemia in Saudi Prediabetic Adults
Published in Genes (02-12-2022)“…Studies suggest that ATP-binding cassette transporter A1 ( C69T) polymorphism is associated with a decreased incidence of type 2 diabetes mellitus (T2DM) and…”
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13
Relative metabolic stability, but disrupted circadian cortisol secretion during the fasting month of Ramadan
Published in PloS one (18-04-2013)“…Chronic feeding and sleep schedule disturbances are stressors that exert damaging effects on the organism. Practicing Muslims in Saudi Arabia go through strict…”
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14
Exploring the Validity of Available Markers and Indices in the Diagnosis of Nonalcoholic Fatty Liver Disease (NAFLD) in People with Type 2 Diabetes in Saudi Arabia
Published in Diseases (15-01-2023)“…Nonalcoholic fatty liver disease (NAFLD) is common among Saudi patients with type 2 diabetes (T2DM). However, recommended clinical procedures to detect it are…”
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15
Impact of smoking cessation, coffee and bread consumption on the intestinal microbial composition among Saudis: A cross-sectional study
Published in PloS one (29-04-2020)“…The gut microbiota is often affected by the dietary and lifestyle habits of the host, resulting in a better efficacy that favors energy harvesting from the…”
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Colossolactone-G synergizes the anticancer properties of 5-fluorouracil and gemcitabine against colorectal cancer cells
Published in Biomedicine & pharmacotherapy (01-08-2021)“…Several terpenoids were isolated from Ganoderma colossum with potential chemotherapeutic properties against different solid tumor cells. Herein, we further…”
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Molecular designing, virtual screening and docking study of novel curcumin analogue as mutation (S769L and K846R) selective inhibitor for EGFR
Published in Saudi journal of biological sciences (01-03-2019)“…The somatic mutations in ATP binding cleft of the tyrosine kinase binding domain of EGFR are known to occur in 15–40% of non-small cell lung cancer (NSCLC)…”
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18
Gender Differences in The Factors associated with Hypertension in Non-Diabetic Saudi Adults—A Cross-Sectional Study
Published in International journal of environmental research and public health (29-10-2021)“…The association between lifestyle practices, obesity and increased BP are under-investigated. We aimed to investigate this association to identify the factors…”
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The Association between Dyslipidemia, Dietary Habits and Other Lifestyle Indicators among Non-Diabetic Attendees of Primary Health Care Centers in Jeddah, Saudi Arabia
Published in Nutrients (13-08-2020)“…Diet and other lifestyle habits have been reported to contribute to the development of dyslipidemia in various populations. Therefore, this study investigated…”
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Dysglycemia risk score in Saudi Arabia: A tool to identify people at high future risk of developing type 2 diabetes
Published in Journal of diabetes investigation (01-07-2020)“…Aims/Introduction To develop a non‐invasive risk score to identify Saudis having prediabetes or undiagnosed type 2 diabetes. Methods Adult Saudis without…”
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