Search Results - "Aizpurúa, M."

Triazole-Directed Pd-Catalyzed C(sp2)–H Oxygenation of Arenes and Alkenes by Irastorza, Aitziber, Aizpurua, Jesús M, Correa, Arkaitz

“…Selective Pd-catalyzed C­(sp2)–H oxygenation of 4-substituted 1,2,3-triazoles is described. Unlike previous metal-catalyzed C–H functionalization events, which…”
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Identifying cardiovascular disease risk and outcome: use of the plasma triglyceride/high‐density lipoprotein cholesterol concentration ratio versus metabolic syndrome criteria by Salazar, M. R., Carbajal, H. A., Espeche, W. G., Aizpurúa, M., Leiva Sisnieguez, C. E., March, C. E., Balbín, E., Stavile, R. N., Reaven, G. M.

“…Background Metabolic syndrome (MetS) has been shown to predict both risk and CVD events. We have identified sex‐specific values for the…”
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Comparison of two surrogate estimates of insulin resistance to predict cardiovascular disease in apparently healthy individuals by Salazar, M.R, Carbajal, H.A, Espeche, W.G, Aizpurúa, M, Dulbecco, C.A, Reaven, G.M

“…Abstract Background and aims Insulin resistance is associated with a cluster of abnormalities that increase cardiovascular disease (CVD). Several indices have…”
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From Bench to Cell: A Roadmap for Assessing the Bioorthogonal “Click” Reactivity of Magnetic Nanoparticles for Cell Surface Engineering by Idiago-López, Javier, Moreno-Antolín, Eduardo, Eceiza, Maite, Aizpurua, Jesús M., Grazú, Valeria, de la Fuente, Jesús M., Fratila, Raluca M.

“…In this work, we report the use of bioorthogonal chemistry, specifically the strain-promoted click azide–alkyne cycloaddition (SPAAC) for the covalent…”
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RGD-Functionalized Fe3O4 nanoparticles for magnetic hyperthermia by Arriortua, Oihane K., Insausti, Maite, Lezama, Luis, Gil de Muro, Izaskun, Garaio, Eneko, de la Fuente, Jesus Martínez, Fratila, Raluca M., Morales, Maria P., Costa, Rocío, Eceiza, Maite, Sagartzazu-Aizpurua, Maialen, Aizpurua, Jesus M.

“…[Display omitted] •Thermal decomposition by successive additions allows obtaining magnetite particles of 11–23 nm.•Preparation of water souble NPs by…”
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Site-Selective N‑Dealkylation of 1,2,3-Triazolium Salts: A Metal-Free Route to 1,5-Substituted 1,2,3-Triazoles and Related Bistriazoles by Monasterio, Zaira, Irastorza, Aitziber, Miranda, José I, Aizpurua, Jesus M

“…N3-Alkylation of 1-(pivaloyloxymethyl)-1,2,3-triazoles with alkyl triflates carrying latent “click” functionality, followed by a nucleophile-promoted…”
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Correction to Triazole-Directed Pd-Catalyzed C(sp2)–H Oxygenation of Arenes and Alkenes by Irastorza, Aitziber, Aizpurua, Jesús M, Correa, Arkaitz

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Use of the triglyceride/high-density lipoprotein cholesterol ratio to identify cardiometabolic risk: impact of obesity? by Salazar, M R, Carbajal, H A, Espeche, W G, Aizpurúa, M, Marillet, A G, Leiva Sisnieguez, C E, Leiva Sisnieguez, B C, Stavile, R N, March, C E, Reaven, G M

“…There is evidence that the plasma concentration ratio of triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) identifies insulin resistance and…”
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Use of direct oral anticoagulants and low molecular weight heparin in venous thromboembolism associated with cancer: real-world evidence in Argentina by Clavijo, M M, Ruiz, J I, Muñoz, C, Vicente Reparaz M de Los, A, Acuña, M A, Casali, C E, Aizpurua, M F, Mahuad, C V, Zerga, M E, Ventura, A, Garate, G M

“…Venous thromboembolism (VTE) and major bleeding (MB) are common in cancer patients. Reduced-doses of antithrombotics as secondary prophylaxis have limited…”
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Cationic 1,2,3-Triazolium Alkynes: Components To Enhance 1,4-Regioselective Azide–Alkyne Cycloaddition Reactions by Monasterio, Zaira, Sagartzazu-Aizpurua, Maialen, Miranda, José I, Reyes, Yuri, Aizpurua, Jesus M

“…4-Alkynyl-1,2,3-triazolium cations undergo thermal [3 + 2] cycloaddition reactions with azides roughly 50- to 100-fold faster than comparable noncharged…”
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Should the first blood pressure reading be discarded? by Salazar, M R, Espeche, W G, Aizpurúa, M, Sisnieguez, C E L, Sisnieguez, B C L, Dulbecco, C A, March, C E, Stavile, R N, Ferrari, E H, Correa, M, Maciel, P M, Balbín, E, Carbajal, H A

“…We evaluated the consequences of excluding the first of three blood pressure (BP) readings in different settings: a random population sample (POS, n =1525), a…”
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Pharmacokinetic Evaluation of New Drugs Using a Multi-Labelling Approach and PET Imaging: Application to a Drug Candidate with Potential Application in Neuromuscular Disorders by Passannante, Rossana, Gómez-Vallejo, Vanessa, Sagartzazu-Aizpurua, Maialen, Vignau Arsuaga, Laura, Marco-Moreno, Pablo, Aldanondo, Garazi, Vallejo-Illarramendi, Ainara, Aguiar, Pablo, Cossío, Unai, Martín, Abraham, Bergare, Jonas, Kingston, Lee, Elmore, Charles S, Morcillo, Miguel Angel, Ferrón, Pablo, Aizpurua, Jesus M, Llop, Jordi

“…The determination of pharmacokinetic properties of new chemical entities is a key step in the process of drug development. Positron emission tomography (PET)…”
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Unusual neuropathological features and increased brain aluminium in a resident of Camelford, UK by King, A., Troakes, C., Aizpurua, M., Mirza, A., Hodges, A., Al‐Sarraj, S., Exley, C.

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Antitumor magnetic hyperthermia induced by RGD-functionalized Fe3O4 nanoparticles, in an experimental model of colorectal liver metastases by Arriortua, Oihane K, Garaio Eneko, Herrero de la Parte Borja, Insausti Maite, Lezama, Luis, Plazaola Fernando, García, Jose Angel, Aizpurua, Jesús M, Maialen, Sagartzazu, Irazola Mireia, Etxebarria Nestor, García-Alonso, Ignacio, Saiz-López, Alberto, Echevarria-Uraga, José Javier

“…This work reports important advances in the study of magnetic nanoparticles (MNPs) related to their application in different research fields such as magnetic…”
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ATRX immunohistochemistry can help refine 'not elsewhere classified' categorisation for grade II/III gliomas by Burford, C., Laxton, R., Sidhu, Z., Aizpurua, M., King, A., Bodi, I., Ashkan, K., Al-Sarraj, S.

“…Purpose: The 2016 WHO tumour classification highlights the role of IDH1/2 gene mutation and 1p/19q co-deletion in classifying grade II/III gliomas. A recent…”
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“Click” Synthesis of Nonsymmetrical Bis(1,2,3-triazoles) by Aizpurua, Jesus M, Azcune, Itxaso, Fratila, Raluca M, Balentova, Eva, Sagartzazu-Aizpurua, Maialen, Miranda, Jose I

“…Unsymmetrically 1,1′-disubstituted 4,4′-bis-1H-1,2,3-triazoles 4 have been prepared from 4-ethynyl-1,2,3-triazoles 5 and azides. Following a “double-click”…”
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Single-Walled Carbon Nanotubes and Multiwalled Carbon Nanotubes Functionalized with Poly(l-lactic acid): a Comparative Study by Olalde, Beatriz, Aizpurua, Jesús M, García, Ainara, Bustero, Izaskun, Obieta, Isabel, Jurado, María J

“…Spectroscopic (Raman) and gravimetric (acid titration, TGA) techniques were compared to determine the functionalization degree of multiwalled carbon nanotubes…”
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Asymmetric synthesis of beta-lactams through the Staudinger reaction and their use as building blocks of natural and nonnatural products by Palomo, C, Aizpurua, J M, Ganboa, I, Oiarbide, M

“…In the last two decades, the better understanding of the mechanistic aspects of the beta-lactams' biological activity and their inhibition, and the chemical…”
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P64 QUANTITATIVE MGMT METHYLATION ANALYSIS BY PYROSEQUENCING REVEALS A STRONG CORRELATION BETWEEN 1P/19Q CO-DELETION AND HIGH LEVEL METHYLATION IN HIGH GRADE GLIOMAS by Laxton, R., Doey, L., Aizpurua, M., Bodi, I., King, A., Chandler, C., Bhangoo, R., Beaney, R., Brazil, L., Ashkan, K., Al-Sarraj, S.

“…INTRODUCTION: Pyrosequencing is a method that allows MGMT methylation to be measured in a quantitative manner. MGMT methylation, along with 1p/19q co-deletion…”
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Primary gastrointestinal aspergillosis 6 months after allogeneic hematopoietic cell transplantation: a case report by Mora, D., Barba, P., Ruiz, I., Castillo, N., Aizpurua, M., Roselló, E., Bosch, F., Valcárcel, D.

“…Invasive fungal infections (IFI) represent one of the most aggressive infectious complications among hematopoietic cell transplantation (HCT) recipients…”
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