Search Results - "Aita, Rohit"

The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac by Chen, Lei, Luo, Shirley, Dupre, Abigail, Vasoya, Roshan P., Parthasarathy, Aditya, Aita, Rohit, Malhotra, Raj, Hur, Joseph, Toke, Natalie H., Chiles, Eric, Yang, Min, Cao, Weihuan, Flores, Juan, Ellison, Christopher E., Gao, Nan, Sahota, Amrik, Su, Xiaoyang, Bonder, Edward M., Verzi, Michael P.

“…The brush border is comprised of microvilli surface protrusions on the apical surface of epithelia. This specialized structure greatly increases absorptive…”
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Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation by Sailaja, Badi Sri, Aita, Rohit, Maledatu, Shane, Ribnicky, David, Verzi, Michael P, Raskin, Ilya

“…This study aims to document the dual mode of pharmacological action of moringa isothiocyanate-1 (MIC-1) derived from seeds of Moringa oleifera Lam. Oral…”
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Genomic analysis of 1,25-dihydroxyvitamin D3 action in mouse intestine reveals compartment and segment-specific gene regulatory effects by Aita, Rohit, Aldea, Dennis, Hassan, Sohaib, Hur, Joseph, Pellon-Cardenas, Oscar, Cohen, Evan, Chen, Lei, Shroyer, Noah, Christakos, Sylvia, Verzi, Michael P., Fleet, James C.

“…1,25-dihydroxyvitamin D (VD) regulates intestinal calcium absorption in the small intestine (SI) and also reduces risk of colonic inflammation and cancer…”
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Moringa isothiocyanate-1 regulates Nrf2 and NF-[kappa]B pathway in response to LPS-driven sepsis and inflammation by Sailaja, Badi Sri, Aita, Rohit, Maledatu, Shane, Ribnicky, David, Verzi, Michael P, Raskin, Ilya

“…This study aims to document the dual mode of pharmacological action of moringa isothiocyanate-1 (MIC-1) derived from seeds of Moringa oleifera Lam. Oral…”
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Sa1800 WHOLE EXOME SEQUENCING OF A MULTIPLEX CROHN'S DISEASE FAMILY IDENTIFIES RARE ALTERATIONS IN PYGB AND XRN2 AS POTENTIALLY HIGH IMPACT RISK VARIANTS OF DISEASE by Chen, Lea Ann, Kim, Minsuk, Li, Dalin, Aita, Rohit, Cataldo, Susan, Radin, Arielle, Baylor, Jessica, Deng, Lily, Hahn, Brett, Wong, Kevin, Tin, Kevin, Mengesha, Emebet, Mcgovern, Dermot P.B.

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WHOLE EXOME SEQUENCING OF A MULTIPLEX CROHN’S DISEASE FAMILY IDENTIFIES RARE ALTERATIONS IN PYGB ANDXRN2 AS POTENTIALLY HIGH IMPACT RISK VARIANTS OF DISEASE by Chen, Lea Ann, Kim, Minsuk, Li, Dalin, Aita, Rohit, Cataldo, Susan, Radin, Arielle, Baylor, Jessica, Deng, Lily, Hahn, Brett, Wong, Kevin, Tin, Kevin, Mengesha, Emebet, McGovern, Dermot

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HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine by Chen, Lei, Toke, Natalie H, Luo, Shirley, Vasoya, Roshan P, Aita, Rohit, Parthasarathy, Aditya, Tsai, Yu-Hwai, Spence, Jason R, Verzi, Michael P

“…As embryos mature, cells undergo remarkable transitions that are accompanied by shifts in transcription factor regulatory networks. Mechanisms driving…”
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WHOLE EXOME SEQUENCING OF A MULTIPLEX CROHN’S DISEASE FAMILY IDENTIFIES RARE ALTERATIONS IN PYGB AND XRN2 AS POTENTIALLY HIGH IMPACT RISK VARIANTS OF DISEASE by Chen, Lea Ann, Kim, Minsuk, Li, Dalin, Aita, Rohit, Cataldo, Susan, Radin, Arielle, Baylor, Jessica, Deng, Lily, Hahn, Brett, Wong, Kevin, Tin, Kevin, Mengesha, Emebet, McGovern, Dermot

“…Abstract BACKGROUND The study of multiplex Crohn’s disease (CD) families has played a critical role in our understanding of the disease, including the…”
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Analysis of 1,25-Dihydroxyvitamin D3 Genomic Action Reveals Calcium-Regulating and Calcium-Independent Effects in Mouse Intestine and Human Enteroids by Li, Shanshan, De La Cruz, Jessica, Hutchens, Steven, Mukhopadhyay, Somshuvra, Criss, Zachary K., Aita, Rohit, Pellon-Cardenas, Oscar, Hur, Joseph, Soteropoulos, Patricia, Husain, Seema, Dhawan, Puneet, Verlinden, Lieve, Carmeliet, Geert, Fleet, James C., Shroyer, Noah F., Verzi, Michael P., Christakos, Sylvia

“…Although vitamin D is critical for the function of the intestine, most studies have focused on the duodenum. We show that transgenic expression of the vitamin…”
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342 UNAFFECTED RELATIVES WITH HIGH IBD POLYGENIC RISK SCORES FROM MULTIPLEX CROHN'S DISEASE FAMILIES CARRY MICROBIOMES THAT PROTECT IL-10 DEFICIENT MICE AGAINST INTESTINAL INFLAMMATION by Chen, Lea Ann, Li, Huilin, Jones, Drew R., Wang, Chan, Li, Dalin, Radin, Arielle, Baylor, Jessica, Deng, Lily, Cataldo, Susan, Kundu, Tanima, Shen, Jing, Bush, Ashley, Aita, Rohit, Hahn, Brett, Ficaro, Lia, Haritunians, Talin, Mengesha, Emebet, Grigoryan, Zoya, Hu, Jiyuan, Sartor, R. Balfour, Mcgovern, Dermot P.B., Blaser, Martin J.

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Developing and pilot testing ASTHMAXcel, a mobile app for adults with asthma by Hsia, Brian, Mowrey, Wenzhu, Keskin, Taha, Wu, Sammy, Aita, Rohit, Kwak, Lily, Ferastraoarou, Denisa, Rosenstreich, David, Jariwala, Sunit P.

“…Objective: We sought to compare the impact of ASTHMAXcel, a novel, guideline-based, patient-facing mobile app to human-delivered asthma education. Methods: We…”
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UNAFFECTED RELATIVES WITH HIGH IBD POLYGENIC RISK SCORES FROM MULTIPLEX CROHN’S DISEASE FAMILIES CARRY MICROBIOMES THAT PROTECT IL-10 DEFICIENT MICE AGAINST INTESTINAL INFLAMMATION by Chen, Lea Ann, Li, Huilin, Jones, Drew, Wang, Chan, Li, Dalin, Radin, Arielle, Baylor, Jessica, Deng, Lily, Cataldo, Susan, Kundu, Tanima, Shen, Jing, Bush, Ashley, Aita, Rohit, Hahn, Brett, Ficaro, Lia, Haritunians, Talin, Mengesha, Emebet, Grigoryan, Zoya, Hu, Jiyuan, Sartor, R. Balfour, McGovern, Dermot, Blaser, Martin

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Analysis of 1,25-Dihydroxyvitamin D 3 Genomic Action Reveals Calcium-Regulating and Calcium-Independent Effects in Mouse Intestine and Human Enteroids by Li, Shanshan, De La Cruz, Jessica, Hutchens, Steven, Mukhopadhyay, Somshuvra, Criss, Zachary K, Aita, Rohit, Pellon-Cardenas, Oscar, Hur, Joseph, Soteropoulos, Patricia, Husain, Seema, Dhawan, Puneet, Verlinden, Lieve, Carmeliet, Geert, Fleet, James C, Shroyer, Noah F, Verzi, Michael P, Christakos, Sylvia

“…Although vitamin D is critical for the function of the intestine, most studies have focused on the duodenum. We show that transgenic expression of the vitamin…”
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Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4 by Chen, Lei, Cao, Weihuan, Aita, Rohit, Aldea, Dennis, Flores, Juan, Gao, Nan, Bonder, Edward M., Ellison, Christopher E., Verzi, Michael P.

“…Cells in renewing tissues exhibit dramatic transcriptional changes as they differentiate. The contribution of chromatin looping to tissue renewal is…”
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UNAFFECTED RELATIVES WITH HIGH IBD POLYGENIC RISK SCORES FROM MULTIPLEX CROHN’S DISEASE FAMILIES CARRY MICROBIOMES THAT PROTECT IL-10 DEFICIENT MICE AGAINST INTESTINAL INFLAMMATION by Chen, Lea Ann, Li, Huilin, Jones, Drew, Wang, Chan, Li, Dalin, Radin, Arielle, Baylor, Jessica, Deng, Lily, Cataldo, Susan, Kundu, Tanima, Shen, Jing, Bush, Ashley, Aita, Rohit, Hahn, Brett, Ficaro, Lia, Haritunians, Talin, Mengesha, Emebet, Grigoryan, Zoya, Hu, Jiyuan, Sartor, R Balfour, McGovern, Dermot, Blaser, Martin

“…Abstract Genetic and environmental influences contribute to Crohn’s disease (CD) development. However, the relationship between these two factors is unclear,…”
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Vitamin D Receptor Binding with DNA in Duodenal Crypt, Duodenal Villi, and Colonic Epithelial Cells of Mice by Aldea, Dennis A., Aita, Rohit, Hassan, Sohaib, Cohen, Evan S., Hur, Joseph, Pellón-Cárdenas, Oscar, Chen, Lei, Verzi, Michael P.

“…Vitamin D receptor (VDR) is a transcription factor that mediates calcium absorption by intestinal epithelial cells. Although calcium absorption is ca-nonically…”
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Genomic analysis of 1,25-dihydroxyvitamin D 3 action in mouse intestine reveals compartment and segment-specific gene regulatory effects by Aita, Rohit, Aldea, Dennis, Hassan, Sohaib, Hur, Joseph, Pellon-Cardenas, Oscar, Cohen, Evan, Chen, Lei, Shroyer, Noah, Christakos, Sylvia, Verzi, Michael P, Fleet, James C

“…1,25-dihydroxyvitamin D (VD) regulates intestinal calcium absorption in the small intestine (SI) and also reduces risk of colonic inflammation and cancer…”
Get full text