Search Results - "Aita, Megumi"

Visualizing Hypothalamic Network Dynamics for Appetitive and Consummatory Behaviors by Jennings, Joshua H., Ung, Randall L., Resendez, Shanna L., Stamatakis, Alice M., Taylor, Johnathon G., Huang, Jonathan, Veleta, Katie, Kantak, Pranish A., Aita, Megumi, Shilling-Scrivo, Kelson, Ramakrishnan, Charu, Deisseroth, Karl, Otte, Stephani, Stuber, Garret D.

“…Optimally orchestrating complex behavioral states, such as the pursuit and consumption of food, is critical for an organism’s survival. The lateral…”
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Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking by Land, Benjamin B, Bruchas, Michael R, Schattauer, Selena, Giardino, William J, Aita, Megumi, Messinger, Daniel, Hnasko, Thomas S, Palmiter, Richard D, Chavkin, Charles

“…Although stress has profound effects on motivated behavior, the underlying mechanisms responsible are incompletely understood. In this study we elucidate a…”
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Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation by Berrios, Janet, Stamatakis, Alice M., Kantak, Pranish A., McElligott, Zoe A., Judson, Matthew C., Aita, Megumi, Rougie, Marie, Stuber, Garret D., Philpot, Benjamin D.

“…Motivated reward-seeking behaviours are governed by dopaminergic ventral tegmental area projections to the nucleus accumbens. In addition to dopamine, these…”
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Partial infraorbital nerve ligation as a model of trigeminal nerve injury in the mouse: behavioral, neural, and glial reactions by Xu, Mei, Aita, Megumi, Chavkin, Charles

“…Trigeminal nerve damage often leads to chronic pain syndromes including trigeminal neuralgia, a severely debilitating chronic orofacial pain syndrome. Options…”
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Enhanced Nociception in Angelman Syndrome Model Mice by McCoy, Eric S, Taylor-Blake, Bonnie, Aita, Megumi, Simon, Jeremy M, Philpot, Benjamin D, Zylka, Mark J

“…Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by mutation or deletion of the maternal allele. The maternal allele is expressed in…”
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A small-molecule screen reveals novel modulators of MeCP2 and X-chromosome inactivation maintenance by Lee, Hyeong-Min, Kuijer, M Bram, Ruiz Blanes, Nerea, Clark, Ellen P, Aita, Megumi, Galiano Arjona, Lorena, Kokot, Agnieszka, Sciaky, Noah, Simon, Jeremy M, Bhatnagar, Sanchita, Philpot, Benjamin D, Cerase, Andrea

“…Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the X-linked methyl-CpG binding protein 2 (MeCP2) gene. While MeCP2 mutations are…”
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Trigeminal Injury Causes kappa Opioid-Dependent Allodynic, Glial and Immune Cell Responses in Mice by Aita, Megumi, Byers, Margaret R, Chavkin, Charles, Xu, Mei

“…Background: The dynorphin-kappa opioid receptor (KOR) system regulates glial proliferation after sciatic nerve injury. Here, we investigated its role in cell…”
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Immunolocalization of aquaporin-1 in the mechanoreceptive Ruffini endings in the periodontal ligament by Nandasena, Batheegama Gammacharige Tharanga Lakmali, Suzuki, Akiko, Aita, Megumi, Kawano, Yoshiro, Nozawa-Inoue, Kayoko, Maeda, Takeyasu

“…Abstract Previous ultrastructural studies have suggested an axon–Schwann cell interaction in the periodontal Ruffini ending, a primary mechanoreceptor…”
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Involvement of neurotrophin-4/5 in regeneration of the periodontal Ruffini endings at the early stage by Jabbar, Shahiqul, Harada, Fumiko, Aita, Megumi, Ohishi, Megumi, Saito, Isao, Kawano, Yoshiro, Suzuki, Akiko, Nozawa-Inoue, Kayoko, Maeda, Takeyasu

“…Little is known about the role of neurotrophin‐4/5 (NT‐4/5) in the regeneration of mechanoreceptors. Therefore, the present study examined the regeneration…”
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The effect of neonatal capsaicin treatment on the CGRP-immunoreaction in the trigeminal subnucleus caudalis of mice by AITA, Megumi, MAEDA, Takeyasu, SEO, Kenji

“…The calcitonin-gene related peptide (CGRP) is a primary afferent neurotransmitter in the trigeminal system. Although a neonatal administration of capsaicin…”
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Postnatal development of substance P-immunoreaction in the trigeminal caudalis of neonatally capsaicin-treated mice by Aita, Megumi, Maeda, Takeyasu, Takagi, Ritsuo, Seo, Kenji

“…The trigeminal subnucleus caudalis (Vc) is a critical relay site for processing nociceptive afferent input from the orofacial area in addition to its…”
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Neurotrophin-4/5-depletion induces a delay in maturation of the periodontal Ruffini endings in mice by Maruyama, Yuko, Harada, Fumiko, Jabbar, Shahiqul, Saito, Isao, Aita, Megumi, Kawano, Yoshiro, Suzuki, Akiko, Nozawa-Inoue, Kayoko, Maeda, Takeyasu

“…Neurotrophin-4/5 (NT-4/5) - a member of the neurotrophic factors - is a ligand for TrkB, which has been reported to be expressed in the mechanoreceptive…”
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Histochemical evidences on the chronological alterations of the hypertrophic zone of mandibular condylar cartilage by Hossain, Kazi Sazzad, Amizuka, Norio, Ikeda, Nobuyki, Nozawa-Inoue, Kayoko, Suzuki, Akiko, Li, Minqi, Takeuchi, Kiichi, Aita, Megumi, Kawano, Yoshiro, Hoshino, Masaaki, Oda, Kimimitsu, Takagi, Ritsuo, Maeda, Takeyasu

“…The hypertrophic chondrocytes lack the ability to proliferate, thus permitting matrix mineralization as well as vascular invasion from the bone in both the…”
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Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria by Bruchas, Michael R, Land, Benjamin B, Aita, Megumi, Xu, Mei, Barot, Sabiha K, Li, Shuang, Chavkin, Charles

“…The molecular mechanisms mediating stress-induced dysphoria in humans and conditioned place aversion in rodents are unknown. Here, we show that repeated swim…”
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Temporal expression of immunoreactivity for heat shock protein 25 (Hsp25) in the rat periodontal ligament following transection of the inferior alveolar nerve by Iijima, Kenji, Harada, Fumiko, Hanada, Kooji, Nozawa-Inoue, Kayoko, Aita, Megumi, Atsumi, Yukako, Wakisaka, Satoshi, Maeda, Takeyasu

“…The present study examined the immunohistochemical localization of heat shock protein 25 (Hsp25) during the regeneration of nerve fibers and Schwann cells in…”
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The Exact Expression of Glial Fibrillary Acidic Protein (GFAP) in Trigeminal Ganglion and Dental Pulp by AJIMA, Hisao, KAWANO, Yoshiro, TAKAGI, Ritsuo, AITA, Megumi, GOMI, Hiroshi, BYERS, Margaret R., MAEDA, Takeyasu

“…The expression in various cell types of peripheral tissues of glial fibrillary acidic protein (GFAP), first discovered as an intermediate filament specific for…”
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Postnatal changes in the spatial distributions of substance P and neurokinin-1 receptor in the trigeminal subnucleus caudalis of mice by Aita, Megumi, Seo, Kenji, Fujiwara, Naoshi, Takagi, Ritsuo, Maeda, Takeyasu

“…Nociceptive afferent signals from the orofacial area are transmitted to the trigeminal subnucleus caudalis (Vc) through the release of glutamate and/or…”
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The Expression of Copper, Zinc Superoxide Dismutase (Cu/Zn-SOD) in the Rat Submandibular Gland by YAMAMOTO, Hitoshi, KAWANO, Yoshiro, NOZAWA-INOUE, Kayoko, AITA, Megumi, MIKI, Yukari, SASAKI, Junzo, MAEDA, Takeyasu

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Characterization of Rat Meibomian Gland Ion and Fluid Transport by Yu, Dongfang, Davis, Richard M, Aita, Megumi, Burns, Kimberlie A, Clapp, Phillip W, Gilmore, Rodney C, Chua, Michael, O'Neal, Wanda K, Schlegel, Richard, Randell, Scott H, C Boucher, Richard

“…We establish novel primary rat meibomian gland (MG) cell culture systems and explore the ion transport activities of the rat MG. Freshly excised rat MG tissues…”
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Expression of GDNF and its receptors in the periodontal mechanoreceptor by Aita, Megumi, Kawano, Yoshiro, Maeda, Takeyasu

“…Our previous studies have revealed the involvement of signaling pathways of BDNF and NT-4/5 via TrkB in the development, regeneration, survival and maintenance…”
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