Search Results - "Aisiku, Omozuanvbo R"
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Identification of a novel binding partner of phospholipase cβ1: translin-associated factor X
Published in PloS one (29-11-2010)“…Mammalian phospholipase Cβ1 (PLCβ1) is activated by the ubiquitous Gα(q) family of G proteins on the surface of the inner leaflet of plasma membrane where it…”
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Journal Article -
2
Effects Of Biased PAR1 Ligands On Platelets and Endothelial Cells
Published in Blood (15-11-2013)“…Protease-activated receptor 1 (PAR1) is a widely expressed G protein coupled receptor (GPCR) that monitors the extracellular protease environment with high…”
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Journal Article -
3
Identification of a Novel Binding Partner of Phospholipase C[beta]1: Translin-Associated Factor X
Published in PloS one (29-11-2010)“…Mammalian phospholipase C[beta]1 (PLC[beta]1) is activated by the ubiquitous G[alpha].sub.q family of G proteins on the surface of the inner leaflet of plasma…”
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Journal Article -
4
Acyl-Protein Thioesterase 1 Functions in Palmitoylation/Depalmitoylation Cycles of G Proteins and Regulates Platelet Activation
Published in Blood (16-11-2012)“…Abstract 1062 Protein palmitoylation is a reversible post-translational modification that regulates both lipid-protein and protein-protein interactions. During…”
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Journal Article -
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An Allosteric Modulator of PAR1 Demonstrates Selective Inhibition of G Protein Coupling and Impairs Thrombus Formation In Vivo
Published in Blood (18-11-2011)“…Abstract 1138 Protease-activated receptor-1 (PAR1) is a widely expressed G protein-coupled receptor (GPCR) that functions in thrombus formation, inflammation,…”
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Journal Article -
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The Identification of a Novel Binding Partner for Phospholipase Cβ1, Translin-Associated Factor X: A Link to RNA Interference
Published 01-01-2010“…Mammalian inositol-specific phospholipase Cβ1 (PLCβ1) is activated by Gαq subunits on the plasma membrane where it catalyzes hydrolysis of the minor membrane…”
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Dissertation