Search Results - "Airey, J E"

Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides by Youssefyeh, R. D, Campbell, H. F, Klein, S, Airey, J. E, Darkes, P, Powers, M, Schnapper, M, Neuenschwander, K, Fitzpatrick, L. R

“…This report describes the development of novel benzamides which are orally active, highly potent, specific antagonists of 5-HT3 receptors. Described in this…”
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Development of high-affinity 5-HT3 receptor antagonists. 2. Two novel tricyclic benzamides by Youssefyeh, Raymond D, Campbell, H. F, Airey, J. E, Klein, S, Schnapper, M, Powers, M, Woodward, R, Rodriguez, W, Golec, S

“…Two new classes of potent 5-HT3 agents have been developed and examined as inhibitors of cytotoxic drug induced emesis in the ferret and dog. The absolute…”
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RG 12915: a potent 5-hydroxytryptamine-3 antagonist that is an orally effective inhibitor of cytotoxic drug-induced emesis in the ferret and dog by Fitzpatrick, L R, Lambert, R M, Pendley, C E, Martin, G E, Bostwick, J S, Gessner, G W, Airey, J E, Youssefyeh, R D, Pendleton, R G, Decktor, D L

“…RG 12915 [4-[N-(1-azabicyclo[2.2.2.]octan-3-(S)-yl)]2-chloro-cis 5a-(S)-9a-(S)-5a,6,7,8,9,9a-hexahydrobenzofurancarboxamide hydrochloride] is a potent and…”
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Structure and absolute configuration of a high affinity 5-HT3 receptor antagonist, (5aS,9aS)-N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2-chloro- 5a,6,7,8,9,9a-hexahydro-4-dibenzofurancarboxamide hydrochloride by Ammon, H L, Youssefyeh, R D, Airey, J E, Studt, W L, Campbell, H F, Powers, M R, Golec, F A

“…The absolute configuration was established as (S,S,S) by the R-factor test and by careful measurement of 197 enantiomorph-sensitive Friedel pairs of…”
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Adriamycin analogues. Novel anomeric ribofuranoside analogues of daunorubicin by Israel, M, Airey, J E, Murray, R J, Gillard, J W

“…The synthesis, cell growth-inhibitory activity, in vivo antileukemic activity, and extent of DNA binding of the alpha- and beta-anomeric…”
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Development of high-affinity 5-HT3 receptor antagonists. I: Initial structure-activity relationship of novel benzamides by YOUSSEFYEH, R. D, CAMPBELL, H. F, MARTIN, G. E, KLEIN, S, AIREY, J. E, DARKES, P, POWERS, M, SCHNAPPER, M, NEUENSCHWANDER, K, FITZPATRICK, L. R, PENDLEY, C. E

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Development of high-affinity 5-HT3 receptor antagonists. II: Two novel tricyclic benzamides by YOUSSEFYEH, R. D, CAMPBELL, H. F, DODSON, S. A, FITZPATRICK, L. R, PENDLEY, C. E, MARTIN, G. E, AIREY, J. E, KLEIN, S, SCHNAPPER, M, POWERS, M, WOODWARD, R, RODRIGUEZ, W, GOLEC, S, STUDT, W

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