Search Results - "Aires, Regina S"
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The water extract and the lectin WSMoL from the seeds of Moringa oleifera prevent the hypertension onset by decreasing renal oxidative stress
Published in Anais da Academia Brasileira de Ciências (01-01-2024)“…Maternal endotoxemia disturbs the intrauterine environment, impairs nephrogenesis, and increases the risk of hypertension and kidney disease in adulthood…”
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Perinatal Na+ overload programs raised renal proximal Na+ transport and enalapril-sensitive alterations of Ang II signaling pathways during adulthood
Published in PloS one (22-08-2012)“…High Na(+) intake is a reality in nowadays and is frequently accompanied by renal and cardiovascular alterations. In this study, renal mechanisms underlying…”
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3
Maternal endotoxemia induces renal collagen deposition in adult offspring: Role of NADPH oxidase/TGF-β1/MMP-2 signaling pathway
Published in Archives of biochemistry and biophysics (15-05-2020)“…Maternal endotoxemia has been shown to increase renal collagen deposition in the offspring. Renal fibrosis is a hallmark of progressive chronic kidney disease…”
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Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol
Published in Biochimica et biophysica acta. Molecular basis of disease (01-12-2018)“…We investigated whether hypertension induced by maternal lipopolysaccharide (LPS) administration during gestation is linked to peripheral vascular and renal…”
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Renal ischemia-reperfusion leads to hypertension and changes in proximal tubule Na+ transport and renin-angiotensin-aldosterone system: Role of NADPH oxidase
Published in Life sciences (1973) (01-02-2021)“…Acute renal injury (AKI) is a risk factor for the development of hypertension, which involves oxidative stress, changes in Na+ handling, and the intrarenal…”
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NO mediates the effect of the synthetic natriuretic peptide NPCdc on kidney and aorta in nephrectomised rats
Published in European journal of pharmacology (05-01-2020)“…NPCdc is a synthetic natriuretic peptide that was originally derived from another peptide, the NP2_Casca, isolated from Crotalus durissus cascavella venom…”
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Perinatal α-tocopherol overload programs alterations in kidney development and renal angiotensin II signaling pathways at birth and at juvenile age: Mechanisms underlying the development of elevated blood pressure
Published in Biochimica et biophysica acta. Molecular basis of disease (01-07-2018)“…α-Tocopherol (α-Toc) overload increases the risk of dying in humans (E.R. Miller III et al. Meta-analysis: high-dosage vitamin E supplementation may increase…”
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Alpha‐Tocopherol during lactation and after weaning alters the programming effect of prenatal high salt intake on cardiac and renal functions of adult male offspring
Published in Clinical and experimental pharmacology & physiology (01-12-2019)“…Maternal salt overload programs cardiovascular and renal alterations in the offspring. However, beneficial and harmful effects of high dose vitamin E…”
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Maternal Na+ intake induces renal function injury in rats prevented by a short‐term angiotensin converting enzyme inhibitor
Published in Clinical and experimental pharmacology & physiology (01-02-2017)“…Summary The Na+‐ATPase, a secondary pump in the proximal tubule, is only weakly responsive to angiotensin II in adult offspring exposed perinatally to high Na+…”
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Perinatal Na.sup.+ Overload Programs Raised Renal Proximal Na.sup.+ Transport and Enalapril-Sensitive Alterations of Ang II Signaling Pathways during Adulthood
Published in PloS one (22-08-2012)“…Background High Na.sup.+ intake is a reality in nowadays and is frequently accompanied by renal and cardiovascular alterations. In this study, renal mechanisms…”
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Journal Article