Search Results - "Aires, André"
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Expanding the genetic spectrum of ALKU syndrome: Compound heterozygosity for two deleterious variants in SMG8 gene
Published in American journal of medical genetics. Part A (01-08-2023)“…Alzahrani–Kuwahara syndrome (ALKUS) is a neurodevelopmental disorder that includes microcephaly, facial dysmorphism, and variable congenital and eye…”
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Basal ganglia calcification: pseudohypoparathyroidism with short fourth metacarpals
Published in Practical neurology (01-06-2023)Get more information
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Sanguinarine: an alkaloid with promising in vitro and in vivo antiparasitic activity against different developmental stages of Schistosoma mansoni and in silico pharmacokinetic properties (ADMET)
Published in Parasitology research (1987) (01-02-2024)“…The objective of the study was to evaluate the in vitro and in vivo schistosomicidal activity of sanguinarine (SA) on Schistosoma mansoni and its in silico…”
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Effects of the probiotic Bacillus cereus GM on experimental schistosomiasis mansoni
Published in Parasitology research (1987) (01-01-2024)“…Probiotics contribute to the integrity of the intestinal mucosa and preventing dysbiosis caused by opportunistic pathogens, such as intestinal helminths…”
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In vitro activity of usnic acid potassium salt against different developmental stages of Schistosoma mansoni: An ultrastructural study
Published in Acta tropica (01-01-2020)“…•Effects of unic acid potassium salt on evolutionary stages of S. mansoni were studied.•In vitro effect of PS-UA was dose and time-dependent.•LC100 at the 24 h…”
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Sublethal concentrations of usnic acid potassium salt impairs physiological parameters of Biomphalaria glabrata (Say, 1818) (Pulmonata: Planorbidae) infected and not infected with Schistosoma mansoni
Published in Acta tropica (01-10-2021)“…Schistosomiasis is a public health problem in many developing countries. The mollusc Biomphalaria glabrata is the most important vector of Schistosoma mansoni…”
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Toxic effect of Croton rudolphianus leaf essential oil against Biomphalaria glabrata, Schistosoma mansoni cercariae and Artemia salina
Published in Acta tropica (01-11-2021)“…•C. rudolphianus EO possesses lethal effects against adults and embryos of B. glabrata.•For B. glabrata adults, LC50 and LC90 were 47.88 and 78.86 μg/mL,…”
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In Vitro Anthelminthic Activity and Ultrastructural Analysis of Barbatic Acid against Schistosomulae and Juvenile Worms of Schistosoma mansoni
Published in Chemistry & biodiversity (01-08-2023)“…Schistosomiasis affects about 260 million people worldwide and the search for new schistosomicidal compounds is urgent. In this study we evaluated the in vitro…”
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Usnic acid potassium salt from Cladonia substellata (Lichen): Synthesis, cytotoxicity and in vitro anthelmintic activity and ultrastructural analysis against adult worms of Schistosoma mansoni
Published in Acta tropica (01-04-2019)“…[Display omitted] •Unic acid (hydrophobic) becomes potassium salt (PS-UA) through a classical reaction.•PS-UA showed antischistosomal activity against…”
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Methanolic Extract of Rhizophora mangle (Rhizophoraceae) Leaves: Phytochemical Characterization and Anthelmintic Evaluation against Schistosoma mansoni
Published in Pharmaceuticals (Basel, Switzerland) (06-09-2024)“…is commonly used in traditional medicine to treat infections, reduce inflammation, and promote healing. This study aimed to analyze the phytochemical profile…”
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Potassium usnate, a water-soluble usnic acid salt, shows enhanced activity against Schistosoma mansoni in vitro
Published in Experimental parasitology (01-01-2020)“…Here, we report enhanced the in vitro effect of potassium usnate on coupled adult Schistosoma mansoni worms at different time intervals and concentrations. The…”
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Schistosomicidal effect of divaricatic acid from Canoparmelia texana (Lichen): In vitro evaluation and ultrastructural analysis against adult worms of Schistosoma mansoni
Published in Acta tropica (01-10-2021)“…•Divaricatic acid exhibited schistosomicidal effect against adult S. mansoni.•Motility changes were observed in S.mansoni at all concentrations after 24…”
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Potassium usnate toxicity against embryonic stages of the snail Biomphalaria glabrata and Schistosoma mansoni cercariae
Published in Acta tropica (01-12-2018)“…[Display omitted] •The toxicity of potassium usnate was evaluated.•Toxic and teratogenic effect in embryonic development B. glabrata were observed.•Hippo stage…”
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In vitro and in vivo evaluation of Bacillus clausii against Schistosoma mansoni
Published in Acta tropica (01-11-2022)“…•In vitro, cell-free culture supernatant of Bacillus clausii does not cause mortality in adult S. mansoni worms.•B. clausii reduces the worm burden in mice…”
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An atypical stroke manifestation: Sleep disturbance in unilateral thalamic lesion
Published in Brain disorders (01-09-2024)“…•Hypersomnia have been described after stroke.•Bilateral paramedian thalamic ischemic lesions can present with hypersomnia.•A strategic unilateral thalamic…”
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Barbatic Acid Offers a New Possibility for Control of Biomphalaria Glabrata and Schistosomiasis
Published in Molecules (Basel, Switzerland) (31-03-2017)“…This study evaluated the biological activity of an ether extract and barbatic acid (BAR) from on embryos and adult mollusks of , cercariae of and the…”
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Schistosomicidal, hepatoprotective and antioxidant activities of the N-acetyl-L-cysteine and/or praziquantel in experimental acute mansonic schistosomiasis
Published in 3 Biotech (01-06-2023)“…Schistosomiasis is a tropical parasitic disease, in which the major clinical manifestation includes hepatosplenomegaly, portal hypertension, and organs…”
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Evaluation of the hydroalcoholic extract of Clarisia racemosa as an antiparasitic agent: an in vitro approach
Published in 3 Biotech (01-12-2023)“…Clarisia racemosa Ruiz & Pav is a neotropical species found in humid forests from southern Mexico to southern Brazil. There are few studies related to the…”
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Eventos Extremos de Secas na Sub-Bacia Hidrográfica do Rio Sucuru, Cariri Paraibano
Published in Revista Brasileira de Meteorologia (2023)“…Resumo Objetivou-se analisar os eventos extremos de secas na sub-bacia hidrográfica do Rio Sucuru durante a série histórica de 1994-2021. Os dados…”
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Plumbagin: A Promising In Vivo Antiparasitic Candidate against Schistosoma mansoni and In Silico Pharmacokinetic Properties (ADMET)
Published in Biomedicines (22-08-2023)“…Schistosomiasis, a potentially fatal chronic disease whose etiological agents are blood trematode worms of the genus Schistosoma spp., is one of the most…”
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