Search Results - "Airavaara, M"

Towards developing a model to study alcohol drinking and craving in female mice housed in automated cages by Koskela, Maryna, Piepponen, T. Petteri, Andressoo, Jaan-Olle, Võikar, Vootele, Airavaara, Mikko

“…•A new model to study cue-induced alcohol craving in the social context was established.•Automated cages and group housing provide a way to study mice behavior…”
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Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity by Mätlik, K, Yu, Li-ying, Eesmaa, A, Hellman, M, Lindholm, P, Peränen, J, Galli, E, Anttila, J, Saarma, M, Permi, P, Airavaara, M, Arumäe, U

“…Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a prosurvival protein that protects the cells when applied intracellularly in vitro or…”
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ARG1 expression in basal forebrain microglia modulates hippocampal innervation and cognition during postnatal development by Venero, J. L., Ruiz, R., Kanatani, S., Osman, A. M., Keane, L., Armengol, J. A., Rodriguez-Moreno, A., Murgoci, A. -N, Garcia-Dominguez, I., Alonso-Bellido, I., Ibañéz, F. González, Picard, K., Vazquez-Cabrera, G., Posada-Perez, M., Vernoux, N., Tejera, D., Grabert, K., Cheray, M., Gonzalez-Rodriguez, P., Pérez-Villegas, E. M., Martinéz-Gallego, I., Lastra-Romero, A., Brodin, D., Avila-Carino, J., Cao, Yang, Airavaara, M., Uhlén, P., Heneka, M. T., Tremblay, M. -È, Blomgren, K., Stratoulias, V., Joseph, B.

“…Diversity within microglia, the resident brain immune cells, is reported. Whether microglial subsets constitute different subtypes with intrinsic properties…”
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2.14.1 NEUROPROTECTIVE AND NEUROREGENERATIVE TROPHIC PROTEINS IN PARKINSON'S DISEASE by Hoffer, B, Airavaara, M, Voutilainen, M.H

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Effects of repeated morphine on locomotion, place preference and dopamine in heterozygous glial cell line‐derived neurotrophic factor knockout mice by Airavaara, M., Tuomainen, H., Piepponen, T. P., Saarma, M., Ahtee, L.

“…Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be involved in the maintenance of striatal dopaminergic neurons. Neurotrophic factors are…”
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3.217 CDNF PROTECTS THE NIGROSTRIATAL DOPAMINE SYSTEM AND PROMOTES RECOVERY AFTER MPTP TREATMENT IN MICE by Airavaara, M, Harvey, B.K, Voutilainen, M.H, Shen, H, Chou, J, Lindholm, P, Lindahl, M, Tuominen, R.K, Saarma, M, Wang, Y, Hoffer, B

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P2.002 Intranigral injection of CDNF promotes functional recovery of nigrostriatal dopaminergic circuit in a lesion model of Parkinson's disease by Bäck, S, Airavaara, M, Miranto, H, Voutilainen, M.H, Hoffer, B, Männistö, P.T, Raasmaja, A, Saarma, M, Tuominen, R.K

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Cross-talk between bioactive lipid mediators and the unfolded protein response in ischemic stroke by Teder, Tarvi, Haeggström, Jesper Z., Airavaara, Mikko, Lõhelaid, Helike

“…Ischemic cerebral stroke is a severe medical condition that affects about 15 million people every year and is the second leading cause of death and disability…”
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Implementation of deep neural networks to count dopamine neurons in substantia nigra by Penttinen, Anna‐Maija, Parkkinen, Ilmari, Blom, Sami, Kopra, Jaakko, Andressoo, Jaan‐Olle, Pitkänen, Kari, Voutilainen, Merja H., Saarma, Mart, Airavaara, Mikko

“…Unbiased estimates of neuron numbers within substantia nigra are crucial for experimental Parkinson's disease models and gene‐function studies. Unbiased…”
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Differential Spinal and Supraspinal Activation of Glia in a Rat Model of Morphine Tolerance by Jokinen, Viljami, Sidorova, Yulia, Viisanen, Hanna, Suleymanova, Ilida, Tiilikainen, Henna, Li, Zhilin, Lilius, Tuomas O., Mätlik, Kert, Anttila, Jenni E., Airavaara, Mikko, Tian, Li, Rauhala, Pekka V., Kalso, Eija A.

“…•Microglial activity was studied using different assays, e.g., immunohistochemistry, transcriptomics, and flow cytometry.•Opioid tolerance and hyperalgesia…”
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Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice by Lindahl, Maria, Chalazonitis, Alcmène, Palm, Erik, Pakarinen, Emmi, Danilova, Tatiana, Pham, Tuan D., Setlik, Wanda, Rao, Meenakshi, Võikar, Vootele, Huotari, Jatta, Kopra, Jaakko, Andressoo, Jaan-Olle, Piepponen, Petteri T., Airavaara, Mikko, Panhelainen, Anne, Gershon, Michael D., Saarma, Mart

“…Cerebral dopamine neurotrophic factor (CDNF) is neuroprotective for nigrostriatal dopamine neurons and restores dopaminergic function in animal models of…”
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The overexpression of GDNF in nucleus accumbens suppresses alcohol-seeking behavior in group-housed C57Bl/6J female mice by Koskela, Maryna, Piepponen, T Petteri, Lindahl, Maria, Harvey, Brandon K, Andressoo, Jaan-Olle, Võikar, Vootele, Airavaara, Mikko

“…Craving for alcohol, in other words powerful desire to drink after withdrawal, is an important contributor to the development and maintenance of alcoholism…”
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Short-term preoperative dietary restriction is neuroprotective in a rat focal stroke model by Varendi, Kärt, Airavaara, Mikko, Anttila, Jenni, Vose, Sarah, Planken, Anu, Saarma, Mart, Mitchell, James R, Andressoo, Jaan-Olle

“…Stroke is a major complication of cardiovascular surgery, resulting in over 100,000 deaths and over a million postoperative encephalopathies annually in the US…”
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P-28 OPIOIDERGIC MODULATION OF ETHANOL INTAKE IN THE NUCLEUS ACCUMBENS OF ALCOHOL-PREFERRING AA RATS by Kiianmaa, K., Uhari-Vaananen, J., Airavaara, M., Backstrom, P., Oinio, V., Raasmaja, A., Piepponen, P.

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Neuronal Activation Stimulates Cytomegalovirus Promoter-Driven Transgene Expression by Bäck, Susanne, Dossat, Amanda, Parkkinen, Ilmari, Koivula, Pyry, Airavaara, Mikko, Richie, Christopher T., Chen, Yun-Hsiang, Wang, Yun, Harvey, Brandon K.

“…The cytomegalovirus (CMV) immediate early promoter has been extensively developed and exploited for transgene expression in vitro and in vivo, including human…”
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In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered by Airavaara, Mikko, Mijatovic, Jelena, Vihavainen, Tanja, Piepponen, Timo Petteri, Saarma, Mart, Ahtee, Liisa

“…Glial cell line‐derived neurotrophic factor (GDNF) regulates striatal dopaminergic neurons. To study whether reduced endogenous GDNF affect morphine's effects…”
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Increased extracellular dopamine concentrations and FosB/ΔFosB expression in striatal brain areas of heterozygous GDNF knockout mice by Airavaara, Mikko, Planken, Anu, Gäddnäs, Helena, Piepponen, Timo Petteri, Saarma, Mart, Ahtee, Liisa

“…Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be involved in the maintenance of striatal dopaminergic neurons. To study whether reduced…”
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