Search Results - "Ainslie, Kylie E C"
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Optimal vaccine allocation for COVID-19 in the Netherlands: A data-driven prioritization
Published in PLoS computational biology (13-12-2021)“…For the control of COVID-19, vaccination programmes provide a long-term solution. The amount of available vaccines is often limited, and thus it is crucial to…”
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Ethical frameworks should be applied to computational modelling of infectious disease interventions
Published in PLoS computational biology (01-03-2024)“…This perspective is part of an international effort to improve epidemiological models with the goal of reducing the unintended consequences of infectious…”
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Evaluating the impact of extended dosing intervals on mRNA COVID-19 vaccine effectiveness in adolescents
Published in BMC medicine (12-09-2024)“…Extending the dosing interval of a primary series of mRNA COVID-19 vaccination has been employed to reduce myocarditis risk in adolescents, but previous…”
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Trends in SARS-CoV-2 infection prevalence during England's roadmap out of lockdown, January to July 2021
Published in PLoS computational biology (01-11-2022)“…Following rapidly rising COVID-19 case numbers, England entered a national lockdown on 6 January 2021, with staged relaxations of restrictions from 8 March…”
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An open source tool to infer epidemiological and immunological dynamics from serological data: serosolver
Published in PLoS computational biology (01-05-2020)“…We present a flexible, open source R package designed to obtain biological and epidemiological insights from serological datasets. Characterising past…”
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The need for a clinical case definition in test-negative design studies estimating vaccine effectiveness
Published in npj vaccines (12-08-2023)“…Test negative studies have been used extensively for the estimation of COVID-19 vaccine effectiveness (VE). Such studies are able to estimate VE against…”
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SARS-CoV-2 antibody prevalence in England following the first peak of the pandemic
Published in Nature communications (10-02-2021)“…England has experienced a large outbreak of SARS-CoV-2, disproportionately affecting people from disadvantaged and ethnic minority communities. It is unclear…”
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Challenges in estimating influenza vaccine effectiveness
Published in Expert review of vaccines (03-06-2019)“…: Influenza vaccination is regarded as the most effective way to prevent influenza infection. Due to the rapid genetic changes that influenza viruses undergo,…”
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Resurgence of SARS-CoV-2: Detection by community viral surveillance
Published in Science (American Association for the Advancement of Science) (28-05-2021)“…Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health…”
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Is annual vaccination best? A modelling study of influenza vaccination strategies in children
Published in Vaccine (09-05-2022)“…Annual vaccination of children against influenza is a key component of vaccination programs in many countries. However, past infection and vaccination may…”
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A comparison of the test-negative and the traditional case-control study designs for estimation of influenza vaccine effectiveness under nonrandom vaccination
Published in BMC infectious diseases (08-12-2017)“…As annual influenza vaccination is recommended for all U.S. persons aged 6 months or older, it is unethical to conduct randomized clinical trials to estimate…”
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Association of COVID-19 vaccination with duration of hospitalization in older adults in Hong Kong
Published in Vaccine (02-04-2024)“…The association between COVID-19 vaccination and length of hospital stay may provide further insight into vaccination benefits, but few studies have…”
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On the bias of estimates of influenza vaccine effectiveness from test–negative studies
Published in Vaccine (19-12-2017)“…•VE against symptomatic influenza may be overestimated in some cases.•Exercise caution when using the TND as VE estimates may have considerable bias. Estimates…”
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Bias of influenza vaccine effectiveness estimates from test-negative studies conducted during an influenza pandemic
Published in Vaccine (28-03-2019)“…Highlights•When vaccination occurs over time, TN-based VE estimates may suffer from some bias. •The timing of beginning vaccination has an unpredictable effect…”
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Evidence of initial success for China exiting COVID-19 social distancing policy after achieving containment
Published in Wellcome open research (2020)“…: The COVID-19 epidemic was declared a Global Pandemic by WHO on 11 March 2020. By 24 March 2020, over 440,000 cases and almost 20,000 deaths had been reported…”
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Anonymised and aggregated crowd level mobility data from mobile phones suggests that initial compliance with COVID-19 social distancing interventions was high and geographically consistent across the UK
Published in Wellcome open research (2020)“…Since early March 2020, the COVID-19 epidemic across the United Kingdom has led to a range of social distancing policies, which have resulted in reduced…”
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Comparing statistical methods for detecting and estimating waning efficacy of rotavirus vaccines in developing countries
Published in Human vaccines & immunotherapeutics (02-11-2021)“…Vaccination has significantly reduced morbidity and mortality resulting from rotavirus infection worldwide. However, rotavirus vaccine efficacy (VE) appears to…”
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Evidence of initial success for China exiting COVID-19 social distancing policy after achieving containment
Published in Wellcome open research (01-10-2020)“…Background : The COVID-19 epidemic was declared a Global Pandemic by WHO on 11 March 2020. By 24 March 2020, over 440,000 cases and almost 20,000 deaths had…”
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The impact of COVID-19 and strategies for mitigation and suppression in low- and middle-income countries
Published in Science (American Association for the Advancement of Science) (24-07-2020)“…The ongoing coronavirus disease 2019 (COVID-19) pandemic poses a severe threat to public health worldwide. We combine data on demography, contact patterns,…”
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Reduction in mobility and COVID-19 transmission
Published in Nature communications (17-02-2021)“…In response to the COVID-19 pandemic, countries have sought to control SARS-CoV-2 transmission by restricting population movement through social distancing…”
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